Search Results - "Vyunova, T. V."

Experimental Zebrafish Models of Mitochondrial Dysfunction in the Pathogenesis of CNS Diseases by Yushko, L. V., Kotova, M. M., Vyunova, T. V., Kalueff, A. V.

“…Mitochondrial dysfunctions are associated with pathogenesis of various brain disorders, including Alzheimer’s, Parkinson’s and Huntington’s diseases,…”
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Synacton and individual activity of synthetic and natural corticotropins by Vyunova, T. V., Andreeva, L. A., Shevchenko, K. V., Myasoedov, N. F.

“…Short endogenous peptides represent one of the most important constituents of the mammalian body's general regulatory system. Some synthesized analogs and…”
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Experimental Zebrafish Models of Synaptopathies by Lebedev, A. S., Kotova, M. M., Kolesnikova, T. O., Ilyin, N. P., Galstyan, D. S., Vyunova, T. V., Petersen, E. V., Kalueff, A. V.

“…Synaptopathies represent a heterogeneous group of severe, debilitating neurological diseases characterized by structural and functional synaptic deficits…”
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Synthesis of deuterium- or tritium-labeled acetylcholine by Shevchenko, V. P., V’yunova, T. V., Nagaev, I. Yu, Shevchenko, K. V., Myasoedov, N. F.

“…Halogenated acetylcholine precursors were synthesized. The prepared deuterium analogs of acetylcholine were characterized by HPLC and mass spectrometry…”
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A possible role of transthyretin in the biological mechanism of regulatory peptide neuroprotection by Vyunova, T. V., Medvedeva, E. V., Andreeva, L. A., Dergunova, L. V., Limborska, S. A., Myasoedov, N. F.

“…The peptide preparation semax has been effectively used for therapy of ischemic stroke. However, the mechanisms of its action are insufficiently understood and…”
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Enzymatic Stability and Possible Molecular Targets of Synthetic Peptide HFRWPGP by V’yunova, T. V., Shevchenko, K. V., Andreeva, L. A., Shevchenko, V. P., Radilov, A. S., Dulov, S. A., Petunov, S. G., Myasoedov, N. F.

“…Molecular aspects of the biological mechanism of action of the synthetic peptide HFRWPGP, including an assessment of the stability to membrane proteolytic…”
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POSSIBLE ROLE OF TRANSTHYRETIN IN THE BIOLOGICAL MECHANISM OF THE REGULATORY PEPTIDE NEUROPROTECTION. by Vyunova, T V, Medvedeva, E V, Andreeva, L A, Dergunova, L V, Limborska, S A, Myasoedov, N F

“…The peptide preparation Semax has been effectively used for therapy of ischemic stroke. However, the mechanisms of its action are insufficiently understood and…”
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Proteolysis of Pro-Gly-Pro-Leu in Rat-Brain Hippocampus, Cerebellum, and Cortex Upon Intranasal Administration by Shevchenko, K. V., V’yunova, T. V., Andreeva, L. A., Nagaev, I. Yu, Shevchenko, V. P., Myasoedov, N. F.

“…The concentrations of Pro-Gly-Pro-Leu (PGPL) tetrapeptide and its metabolites (Gly-Pro-Leu, Pro-Gly-Pro, Gly-Pro, and Pro-Gly) in various rat-brain…”
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Penetration of thyroliberin in the blood and brain regions at intranasal or intravenous administration by Shevchenko, K. V., Vyunova, T. V., Radilov, A. S., Andreeva, L. A., Nagaev, I. Yu, Shevchenko, V. P., Rembovsky, V. R., Myasoedov, N. F.

“…The maximum amounts of the thyroliberin in the blood and brain of rats at intranasal and intravenous administration were determined. It is found that rat…”
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Characteristic features of specific binding of pentapeptide HFPGP labeled at the C-terminal proline residue to rat forebrain plasma membranes by Vyunova, T. V., Andreeva, L. A., Shevchenko, K. V., Shevchenko, V. P., Bobrov, M. Yu, Bezuglov, V. V., Myasoedov, N. F.

“…The aim of this work was to study the characteristics of the specific binding of the pentapeptide HFPGP with plasma membranes of various regions of rat brain…”
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Proteolysis of Pro-Gly-Pro-Leu in the Hippocampus, Cerebellum, and Cerebral Cortex in Rats after Intravenous Injection by Shevchenko, K. V., V’yunova, T. V., Andreeva, L. A., Nagaev, I. Yu, Shevchenko, V. P., Myasoedov, N. F.

“…We studied the dependence of the levels of Pro-Gly-Pro-Leu peptide and its metabolites (Gly-Pro-Leu, Pro-Gly-Pro, Gly-Pro and Pro-Gly) from the time of…”
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Comparison of pharmacokinetics and metabolism of Pro-Gly-Pro-Leu administered intranasally and intravenously in the blood and brain of rats by Shevchenko, K. V., V’yunova, T. V., Andreeva, L. A., Nagaev, I. Yu, Shevchenko, V. P., Myasoedov, N. F.

“…The aim of this work was to compare the pharmacokinetics parameters and metabolism of intranasally and intravenously administered Pro Gly Pro Leu in the blood…”
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The synthesis and study of simple glyprolines by V’yunova, T. V., Andreeva, L. A., Shevchenko, K. V., Shevchenko, V. P., Myasoedov, N. F.

“…We validated the structure and performed synthesis of eight new peptides that are analogues of proglyprol, with the common formula of Pro(X)-A-Pro(Y). Here we…”
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Peptide regulation of specific ligand-receptor interactions of GABA with the plasma membranes of nerve cells by V’yunova, T. V., Andreeva, L. A., Shevchenko, K. V., Shevchenko, V. P., Myasoedov, N. F.

“…Here we studied the role of peptide anxiolytics (Selank and its short fragment, Arg-Pro-Gly-Pro) in the occurrence of direct and indirect changes in the basic…”
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Specific binding of semax in different regions of the rat brain by V'yunova, T V, Shevchenko, K V, Shevchenko, V P, Bobrov, M Yu, Bezuglov, V V, Myasoedov, N F

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Proteolysis of simple glyprolines by leucine aminopeptidase and enzymes from nasal mucus, brain membranes, and blood of rats by Shevchenko, K. V., V’yunova, T. V., Nagaev, I. Yu, Andreeva, L. A., Myasoedov, N. F.

“…Proteolysis of Pro-Gly-Pro-Leu, Pro-Gly-Pro-Gly and Pro-Gly-Pro compared to Met-Glu-His-Phe-Pro-Gly-Pro (Semax) has been studied. It is shown that all three…”
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Studies of the aminopeptidase proteolysis of semax analogues with different N-terminal amino acid residues by Shevchenko, K. V., V’yunova, T. V., Nagaev, I. Yu, Andreeva, L. A., Alfeeva, L. Yu, Myasoedov, N. F.

“…Proteolysis of semax (Met-Glu-His-Phe-Pro-Gly-Pro, Sem) and its analogues with the substitution of Ala, Gly, Thr, or Trp for the N -terminal Met was studied…”
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A biotechnological procedure for preparing short peptides and their radioactively labeled analogs for estimating specific binding of Semax and its metabolites in various sections of rat brain by V’yunova, T. V., Shevchenko, K. V., Shevchenko, V. P., Bezuglov, V. V., Myasoedov, N. F.

“…The peptides His-Phe-Pro-Gly-Pro and Phe-Pro-Gly-Pro, as well as their tritium-labeled analogs, were prepared by biotechnological methods from peptides of the…”
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Arachidonoyl amino acids and arachidonoyl peptides: Synthesis and properties by Bezuglov, V. V., Gretskaya, N. M., Blazhenova, A. V., Andrianova, E. L., Akimov, M. G., Bobrov, M. Yu, Nazimov, I. V., Kisel’, M. A., Sharko, O. L., Novikov, A. V., Krasnov, N. V., Shevchenko, V. P., Shevchenko, K. V., V’yunova, T. V., Myasoedov, N. F.

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