Search Results - "Vymětalová, Ladislava"
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Large-Scale Automated Hollow-Fiber Bioreactor Expansion of Umbilical Cord-Derived Human Mesenchymal Stromal Cells for Neurological Disorders
Published in Neurochemical research (01-01-2020)“…Neurodegenerative disorders present a broad group of neurological diseases and remain one of the greatest challenges and burdens to mankind. Maladies like…”
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Transcription factor c-Myb: novel prognostic factor in osteosarcoma
Published in Clinical & experimental metastasis (01-04-2022)“…The transcription factor c-Myb is an oncoprotein promoting cell proliferation and survival when aberrantly activated/expressed, thus contributing to malignant…”
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5-Substituted 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidines with anti-proliferative activity as potent and selective inhibitors of cyclin-dependent kinases
Published in European journal of medicinal chemistry (03-03-2016)“…A series of 5-substituted 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidine derivatives was synthesized and evaluated for their…”
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Potential Clinical Uses of CDK Inhibitors: Lessons from Synthetic Lethality Screens
Published in Medicinal research reviews (01-11-2015)“…Developments in genetic and genomic technology have produced vast quantities of data that are gradually yielding new insights into fundamental cellular and…”
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Structural Basis of the Interaction of Cyclin‐Dependent Kinase 2 with Roscovitine and Its Analogues Having Bioisosteric Central Heterocycles
Published in Chemphyschem (05-04-2017)“…The structural basis for the interaction of roscovitine and analogues containing 13 different bioisosteric central heterocycles with the enzyme…”
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Stem cells and neurodegenerative disorders: From basic research, large-scale cells expansion to clinical testing
Published in IBRO reports (01-09-2019)Get full text
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