Search Results - "Vyas, Vinay"

IL-15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization by Han, Kai-ping, Zhu, Xiaoyun, Liu, Bai, Jeng, Emily, Kong, Lin, Yovandich, Jason L., Vyas, Vinay V., Marcus, Warren D., Chavaillaz, Pierre-Andre, Romero, Christian A., Rhode, Peter R., Wong, Hing C.

“…► Soluble IL-15:IL-15Rα superagonist complex was produced at high levels in CHO cells. ► The highly purified superagonist complex has long serum half-life in…”
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Identification of vacancy defects in carbon nanotubes using vibration analysis and machine learning by Singh, Sneha, Junaid, Zaid Bin, Vyas, Vinay, Kalyanwat, Teekam Singh, Rana, Subhram Subhrajyoti

“…Point vacancies are the most common defects in a carbon nanotube (CNT) lattice. However, there is no standard technique to identify these defects. Moreover,…”
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Bilateral inguinal lymphadenopathy presenting as tuberculosis in a case of carcinoma rectum by Vyas, Sunil, Umashankar, Narendra, Kothari, Nirupama, Vyas, Vinay

“…Isolated bilateral inguinal tubercular lymphadenitis is a very rare presentation. A 59-year-old male, on treatment for Carcinoma rectum (T3 N1 M0) presented…”
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Characterization of Recombinant Human IL-15 Deamidation and Its Practical Elimination through Substitution of Asparagine 77 by Nellis, David F., Michiel, Dennis F., Jiang, Man-Shiow, Esposito, Dominic, Davis, Richard, Jiang, Hengguang, Korrell, Angela, Knapp, George C., Lucernoni, Lauren E., Nelson, Roy E., Pritt, Emily M., Procter, Lauren V., Rogers, Mark, Sumpter, Terry L., Vyas, Vinay V., Waybright, Timothy J., Yang, Xiaoyi, Zheng, Amy M., Yovandich, Jason L., Gilly, John A., Mitra, George, Zhu, Jianwei

“…ABSTRACT Purpose The use of recombinant human interleukin (rhIL)-15 as a potential therapeutic immune modulator and anticancer agent requires pure, stable…”
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Clinical manufacturing of recombinant human interleukin 15. I. Production cell line development and protein expression in E. coli with stop codon optimization by Vyas, Vinay V., Esposito, Dominic, Sumpter, Terry L., Broadt, Trevor L., Hartley, James, Knapp IV, George C., Cheng, Wei, Jiang, Man-Shiow, Roach, John M., Yang, Xiaoyi, Giardina, Steven L., Mitra, George, Yovandich, Jason L., Creekmore, Stephen P., Waldmann, Thomas A., Zhu, Jianwei

“…Interleukin 15 (IL‐15) has shown remarkable biological properties of promoting NK‐ and T‐cell activation and proliferation, as well as enhancing antitumor…”
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Purification and protective efficacy of monomeric and modified Yersinia pestis capsular F1-V antigen fusion proteins for vaccination against plague by Goodin, Jeremy L., Nellis, David F., Powell, Bradford S., Vyas, Vinay V., Enama, Jeffrey T., Wang, Lena C., Clark, Patrick K., Giardina, Steven L., Adamovicz, Jeffery. J., Michiel, Dennis F.

“…The F1-V vaccine antigen, protective against Yersinia pestis, exhibits a strong tendency to multimerize that affects larger-scale manufacture and…”
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Entropically Assisted Carbohydrate Recognition by a Natural Killer Cell-Surface Receptor by Swaminathan, Chittoor P, Wais, Neelowfar, Vyas, Vinay V, Velikovsky, Carlos A, Moretta, Alessandro, Moretta, Lorenzo, Biassoni, Roberto, Mariuzza, Roy A, Dimasi, Nazzareno

“…Brake‐assisted drive. Saccharide recognition by lectins involves several critical hydrogen‐bonding interactions. This manifests as favorable enthalpic…”
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CD4+/CD8+ Selection of Anti-AML ENG-T Cells Affects Long-Term T-Cell Persistence in Vitro and Survival in an AML Xenograft Model by Holl, Natalie J., Fearnow, Adam, Vorri, Stamatia C., Rahnama, Ruyan, Christodoulou, Ilias, Choe, Jun, Ghosal, Alokesh, Ng, Cynthia, Modi, Arjun, Vyas, Vinay, Bonifant, Challice L.

“…Background: Immunotherapies have shown dramatic anti-cancer efficacy in pediatric hematopoietic malignancies. Despite initial disease clearance, relapse rates…”
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Regenerative responses of rabbit corneal endothelial cells to stimulation by fibroblast growth factor 1 (FGF1) derivatives, TTHX1001 and TTHX1114 by Weant, Jessica, Eveleth, David D., Subramaniam, Amuthakannan, Jenkins-Eveleth, Jennifer, Blaber, Michael, Li, Ling, Ornitz, David M., Alimardanov, Asaf, Broadt, Trevor, Dong, Hui, Vyas, Vinay, Yang, Xiaoyi, Bradshaw, Ralph A.

“…Utilising rabbit corneal endothelial cells (CEC) in three different paradigms, two human FGF1 derivatives (TTHX1001 and TTHX1114), engineered to exhibit…”
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MTS dye based colorimetric CTLL-2 cell proliferation assay for product release and stability monitoring of Interleukin-15: Assay qualification, standardization and statistical analysis by Soman, Gopalan, Yang, Xiaoyi, Jiang, Hengguang, Giardina, Steve, Vyas, Vinay, Mitra, George, Yovandich, Jason, Creekmore, Stephen P., Waldmann, Thomas A., Quiñones, Octavio, Alvord, W. Gregory

“…A colorimetric cell proliferation assay using soluble tetrazolium salt [(CellTiter 96® Aqueous One Solution) cell proliferation reagent, containing the…”
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NMR Structure of the Natural Killer Cell Receptor 2B4 (CD244):  Implications for Ligand Recognition by Ames, James B, Vyas, Vinay, Lusin, Jacqueline D, Mariuzza, Roy

“…2B4, a transmembrane receptor expressed primarily on natural killer (NK) cells and on a subset of CD8+ T cells, plays an important role in activating…”
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15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization by Han, Kai-ping, Zhu, Xiaoyun, Liu, Bai, Jeng, Emily, Kong, Lin, Yovandich, Jason L, Vyas, Vinay V, Marcus, Warren D, Chavaillaz, Pierre-Andre, Romero, Christian A, Rhode, Peter R, Wong, Hing C

“…IL-15, a promising cytokine for treating cancer and viral diseases, is presented in trans by the IL-15 receptor (IL-15R) alpha-chain to the IL-15Rβγc complex…”
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NMR Structure of the Natural Killer Cell Receptor 2B4 (CD244):  Implications for Ligand Recognition by Ames, James B, Vyas, Vinay, Lusin, Jacqueline D, Mariuzza, Roy

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Bilateral inguinal lymphadenopathy presenting as tuberculosis in a case of carcinoma rectum by Vyas, Sunil, Umashankar, Narendra, Kothari, Nirupama, Vyas, Vinay

“…Isolated bilateral inguinal tubercular lymphadenitis is a very rare presentation. A 59-year-old male, on treatment for Carcinoma rectum (T3 N1 M0) presented…”
Get full text