Search Results - "Vyčítal, Ondřej"

Targeted panel sequencing of pharmacogenes and oncodrivers in colorectal cancer patients reveals genes with prognostic significance by Heczko, Lucie, Liška, Václav, Vyčítal, Ondřej, Fiala, Ondřej, Šůsová, Simona, Hlaváč, Viktor, Souček, Pavel

“…Colorectal cancer is still the second leading cause of cancer-related deaths and thus biomarkers allowing prediction of the resistance of patients to therapy…”
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Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases by Heczko, Lucie, Hlaváč, Viktor, Holý, Petr, Dvořák, Pavel, Liška, Václav, Vyčítal, Ondřej, Fiala, Ondřej, Souček, Pavel

“…Abstract Background Colorectal cancer is a highly prevalent and deadly. The most common metastatic site is the liver. We performed a whole exome sequencing…”
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Mesenchymal Stromal Cell Therapy in Novel Porcine Model of Diffuse Liver Damage Induced by Repeated Biliary Obstruction by Vištejnová, Lucie, Liška, Václav, Kumar, Arvind, Křečková, Jana, Vyčítal, Ondřej, Brůha, Jan, Beneš, Jan, Kolinko, Yaroslav, Blassová, Tereza, Tonar, Zbyněk, Brychtová, Michaela, Karlíková, Marie, Racek, Jaroslav, Mírka, Hynek, Hošek, Petr, Lysák, Daniel, Králíčková, Milena

“…In liver surgery, biliary obstruction can lead to secondary biliary cirrhosis, a life-threatening disease with liver transplantation as the only curative…”
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Exome Sequencing of Paired Colorectal Carcinomas and Synchronous Liver Metastases for Prognosis and Therapy Prediction by Hlaváč, Viktor, Červenková, Lenka, Šůsová, Simona, Holý, Petr, Liška, Václav, Vyčítal, Ondřej, Šorejs, Ondřej, Fiala, Ondřej, Daum, Ondřej, Souček, Pavel

“…Analysis of somatic variant profiles in retrospectively collected pairs of primary tumors and synchronous liver metastases from surgically treated patients…”
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Circulating Tumor Cell Kinetics and Morphology from the Liquid Biopsy Predict Disease Progression in Patients with Metastatic Colorectal Cancer Following Resection by Kolenčík, Drahomír, Narayan, Sachin, Thiele, Jana-Aletta, McKinley, Dillon, Gerdtsson, Anna Sandström, Welter, Lisa, Hošek, Petr, Ostašov, Pavel, Vyčítal, Ondřej, Brůha, Jan, Fiala, Ondřej, Šorejs, Ondřej, Liška, Václav, Pitule, Pavel, Kuhn, Peter, Shishido, Stephanie N

“…The liquid biopsy has the potential to improve current clinical practice in oncology by providing real-time personalized information about a patient's disease…”
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Prognostic assessment of T‐cells in primary colorectal cancer and paired synchronous or metachronous liver metastasis by Trailin, Andriy, Ali, Esraa, Ye, Wenjing, Pavlov, Sergii, Červenková, Lenka, Vyčítal, Ondřej, Ambrozkiewicz, Filip, Hošek, Petr, Daum, Ondřej, Liška, Václav, Hemminki, Kari

“…Abstract Prognostic value of T‐cells between primary colorectal cancer (pCRC) and its paired synchronous and metachronous liver metastasis (LM) is…”
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Protein expression of ABCC2 and SLC22A3 associates with prognosis of pancreatic adenocarcinoma by Cervenkova, Lenka, Vycital, Ondrej, Bruha, Jan, Rosendorf, Jachym, Palek, Richard, Liska, Vaclav, Daum, Ondrej, Mohelnikova-Duchonova, Beatrice, Soucek, Pavel

“…ATP-binding cassette (ABC) and solute carrier (SLC) transporters translocate diverse substances across cellular membranes and their deregulation may cause drug…”
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lncRNAs in Non-Malignant Tissue Have Prognostic Value in Colorectal Cancer by Thiele, Jana-Aletta, Hosek, Petr, Kralovcova, Eva, Ostasov, Pavel, Liska, Vaclav, Bruha, Jan, Vycital, Ondrej, Rosendorf, Jachym, Opattova, Alena, Horak, Josef, Kralickova, Milena, Vodicka, Pavel, Pitule, Pavel

“…Although colorectal cancer (CRC) is the third most frequent cause of cancer related death in Europe, clinically relevant biomarkers for therapy guidance and…”
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Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer by Catalano, Calogerina, da Silva Filho, Miguel Inacio, Frank, Christoph, Jiraskova, Katerina, Vymetalkova, Veronika, Levy, Miroslav, Liska, Vaclav, Vycital, Ondrej, Naccarati, Alessio, Vodickova, Ludmila, Hemminki, Kari, Vodicka, Pavel, Weber, Alexander N R, Försti, Asta

“…Constitutive activation of interferon signaling pathways has been reported in colorectal cancer (CRC), leading to a strong CD8+ T cell response through…”
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The association of miR-126-3p, miR-126-5p and miR-664-3p expression profiles with outcomes of patients with metastatic colorectal cancer treated with bevacizumab by Fiala, Ondrej, Pitule, Pavel, Hosek, Petr, Liska, Vaclav, Sorejs, Ondrej, Bruha, Jan, Vycital, Ondrej, Buchler, Tomas, Poprach, Alexandr, Topolcan, Ondrej, Finek, Jindrich

“…MicroRNAs regulate the expression of genes involved in several important cancer-related processes including cell adhesion, proliferation, and tumour…”
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Epistatic effect of TLR3 and cGAS‐STING‐IKKε‐TBK1‐IFN signaling variants on colorectal cancer risk by Catalano, Calogerina, Silva Filho, Miguel Inacio, Frank, Christoph, Lu, Shun, Jiraskova, Katerina, Vymetalkova, Veronika, Levy, Miroslav, Liska, Vaclav, Vycital, Ondrej, Naccarati, Alessio, Vodickova, Ludmila, Hemminki, Kari, Vodicka, Pavel, Weber, Alexander N. R., Försti, Asta

“…Objective The TLR3/cGAS‐STING‐IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes…”
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Interleukin-6 Augments Activation of Liver Regeneration in Porcine Model of Partial Portal Vein Ligation by LISKA, Vaclav, TRESKA, Vladislav, CHLUMSKA, Alena, HOLUBEC, Lubos, MATEJOVIC, Martin, MIRKA, Hynek, KOBR, Jiri, SYKORA, Roman, SKALICKY, Tomas, SUTNAR, Alan, BRUHA, Jan, FIALA, Ondrej, VYCITAL, Ondrej

“…Background: Portal vein ligation (PVL) could multiply the future liver remnant volume (FLRV). Interuleukin-6 (IL-6) is a pleiotropic cytokine that is…”
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HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients by Svoboda, Miroslav, Slyskova, Jana, Schneiderova, Michaela, Makovicky, Peter, Bielik, Ludovit, Levy, Miroslav, Lipska, Ludmila, Hemmelova, Beata, Kala, Zdenek, Protivankova, Marketa, Vycital, Ondrej, Liska, Vaclav, Schwarzova, Lucie, Vodickova, Ludmila, Vodicka, Pavel

“…Colorectal cancer (CRC) is one of the main causes of death of neoplasia. Demand for predictive and prognostic markers to reverse this trend is increasing. Long…”
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Relationship of telomere length in colorectal cancer patients with cancer phenotype and patient prognosis by Kroupa, Michal, Rachakonda, Sivarama Krishna, Liska, Vaclav, Srinivas, Nalini, Urbanova, Marketa, Jiraskova, Katerina, Schneiderova, Michaela, Vycital, Ondrej, Vymetalkova, Veronika, Vodickova, Ludmila, Kumar, Rajiv, Vodicka, Pavel

“…Background Telomeres, repetitive DNA capping ends of eukaryotic chromosomes, are important in the maintenance of genomic integrity. Perturbed telomeres are…”
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Expression of Serpin B9 as a Prognostic Factor of Colorectal Cancer by Vycital, Ondrej, Pitule, Pavel, Hosek, Petr, Kriz, Tomas, Treska, Vladislav, Liska, Vaclav

“…Background/Aim: Treatment of colorectal cancer (CRC) does not reflect immune interactions between tumours and macro-organisms. Serpin B9 is known as an…”
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A Fecal MicroRNA Signature by Small RNA Sequencing Accurately Distinguishes Colorectal Cancers: Results From a Multicenter Study by Pardini, Barbara, Ferrero, Giulio, Tarallo, Sonia, Gallo, Gaetano, Francavilla, Antonio, Licheri, Nicola, Trompetto, Mario, Clerico, Giuseppe, Senore, Carlo, Peyre, Sergio, Vymetalkova, Veronika, Vodickova, Ludmila, Liska, Vaclav, Vycital, Ondrej, Levy, Miroslav, Macinga, Peter, Hucl, Tomas, Budinska, Eva, Vodicka, Pavel, Cordero, Francesca, Naccarati, Alessio

“…Fecal tests currently used for colorectal cancer (CRC) screening show limited accuracy in detecting early tumors or precancerous lesions. In this respect, we…”
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The Impact of Immune Interaction on the Metastatic Infiltration of Colorectal Carcinoma to Lymph Nodes by Vycital, Ondrej, Dubova, Magdalena, Palek, Richard, Hosek, Petr, Branzovsky, Jindrich, Treska, Vladislav, Daum, Ondrej, Liska, Vaclav

“…Tumour-infiltrating lymphocytes (TILs) and Granzyme B play crucial roles in immune reactions against colorectal carcinoma (CRCa). The inhibitor of Granzyme B…”
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The Level of Preoperative Plasma KRAS Mutations and CEA Predict Survival of Patients Undergoing Surgery for Colorectal Cancer Liver Metastases by Polivka, Jiri, Windrichova, Jindra, Pesta, Martin, Houfkova, Katerina, Rezackova, Hana, Macanova, Tereza, Vycital, Ondrej, Kucera, Radek, Slouka, David, Topolcan, Ondrej

“…Colorectal cancer (CRC) belongs to the most common cancers. The liver is a predominant site of CRC dissemination. Novel biomarkers for predicting the survival…”
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Abstract 1470: Relative telomere length in tumor tissue and adjacent mucosa of colorectal cancer patients by Kroupa, Michal, Liska, Vaclav, Rachakonda, Krishna, Urbanova, Marketa, Schneiderova, Michaela, Jiraskova, Katerina, Vycital, Ondrej, Vodickova, Ludmila, Kumar, Rajiv, Vodicka, Pavel

“…Abstract Colorectal cancer (CRC) represents a major public health problem, being the fourth leading cause of cancer related deaths mainly due to the late…”
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Abstract 5528: Adaptive immune cells in colorectal cancer between normal mucosa, primary tumor and liver metastasis by Trailin, Andriy, Ye, Wenjing, Ali, Esraa, Pavlov, Sergii, Cervenkova, Lenka, Ambrozkiewicz, Filip, Vycital, Ondrej, Daum, Ondrej, Liska, Vaclav, Hemminki, Kari

“…Abstract Introduction: We aimed to assess the role of local adaptive immunity in the metastatic process by comparing densities of adaptive immune cells between…”
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