Search Results - "Vuorimaa, Anna"
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Positron emission tomography imaging in evaluation of MS pathology in vivo
Published in Multiple Sclerosis Journal (01-10-2018)“…Positron emission tomography (PET) gives an opportunity to quantitate the expression of specific molecular targets in vivo and longitudinally in brain and thus…”
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Book Review Journal Article -
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Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis
Published in Brain (London, England : 1878) (01-11-2020)“…Overactivation of microglia is associated with most neurodegenerative diseases. In this study we examined whether PET-measurable innate immune cell activation…”
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Association of serum neurofilament light with microglial activation in multiple sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-09-2023)“…BackgroundTranslocator protein (TSPO)-PET and neurofilament light (NfL) both report on brain pathology, but their potential association has not yet been…”
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Journal Article -
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In Vivo PET Imaging of Adenosine 2A Receptors in Neuroinflammatory and Neurodegenerative Disease
Published in Contrast media and molecular imaging (01-01-2017)“…Adenosine receptors are G-protein coupled P1 purinergic receptors that are broadly expressed in the peripheral immune system, vasculature, and the central…”
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Longitudinal stability of progression‐related microglial activity during teriflunomide treatment in patients with multiple sclerosis
Published in European journal of neurology (01-08-2023)“…Background and purpose The aim was to study brain innate immune cell activation in teriflunomide‐treated patients with relapsing–remitting multiple sclerosis…”
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High serum neurofilament associates with diffuse white matter damage in MS
Published in Neurology : neuroimmunology & neuroinflammation (01-01-2021)“…To evaluate to which extent serum neurofilament light chain (NfL) increase is related to diffusion tensor imaging-MRI measurable diffuse normal-appearing white…”
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Journal Article -
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Natalizumab treatment reduces microglial activation in the white matter of the MS brain
Published in Neurology : neuroimmunology & neuroinflammation (01-07-2019)“…OBJECTIVETo evaluate whether natalizumab treatment reduces microglial activation in MS. METHODSWe measured microglial activation using the 18-kDa translocator…”
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Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging
Published in Neurology : neuroimmunology & neuroinflammation (01-05-2020)“…To evaluate in vivo the co-occurrence of microglial activation and microstructural white matter (WM) damage in the MS brain and to examine their association…”
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Journal Article