Search Results - "Vuori, Kristiina"
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Identification of modifiable pre- and postnatal dietary and environmental exposures associated with owner-reported canine atopic dermatitis in Finland using a web-based questionnaire
Published in PloS one (29-05-2020)“…A cross-sectional hypothesis generating study was performed to investigate modifiable exposures such as whether feeding pattern (a non-processed meat based…”
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Novel Role of Src in Priming Pyk2 Phosphorylation
Published in PloS one (11-02-2016)“…Proline-rich tyrosine kinase 2 (Pyk2) is a member of the focal adhesion kinase (FAK) family of non-receptor tyrosine kinases and plays an important role in…”
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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways
Published in Trends in cell biology (01-08-2007)“…Rho GTPase activation, which is mediated by guanine nucleotide exchange factors (GEFs), is tightly regulated in time and space. Although Rho GTPases have a…”
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The effect of puppyhood and adolescent diet on the incidence of chronic enteropathy in dogs later in life
Published in Scientific reports (09-02-2023)“…Diet has a key role in the homeostasis of the gut microenvironment, influencing the microbiome, the gut barrier, host immunity and gut physiology. Yet, there…”
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The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors
Published in Nature communications (13-09-2021)“…Acute myeloid leukemia (AML) remains incurable, largely due to its resistance to conventional treatments. Here, we find that increased abundance of the…”
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3-Dimensional culture systems for anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxicity compared to monolayer culture systems
Published in PloS one (23-09-2014)“…3-dimensional (3D) culture models have the potential to bridge the gap between monolayer cell culture and in vivo studies. To benefit anti-cancer drug…”
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Diet and dog characteristics affect major and trace elements in hair and blood of healthy dogs
Published in Veterinary research communications (01-02-2022)“…Obtaining correct amounts of essential elements, and avoiding toxic metals are key factors in dog health. Through analyzing major and trace elements in hair…”
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Oxidative stress and antioxidant defense responses in Acartia copepods in relation to environmental factors
Published in PloS one (13-04-2018)“…On a daily basis, planktonic organisms migrate vertically and thus experience widely varying conditions in their physico-chemical environment. In the Gulf of…”
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Multi-level assessment of the origin, feeding area and organohalogen contamination on salmon from the Baltic Sea
Published in Ecotoxicology and environmental safety (01-10-2023)“…The Atlantic salmon (Salmo salar) population in the Baltic Sea consists of wild and hatchery-reared fish that have been released into the sea to support salmon…”
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Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells
Published in Oncogene (16-08-2001)“…Inherent or acquired drug resistance is one of the major problems in chemotherapy. The mechanisms by which cancer cells survive and escape the cytotoxic…”
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Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells
Published in Nature communications (19-09-2017)“…Phagocytic clearance of apoptotic germ cells by Sertoli cells is vital for germ cell development and differentiation. Here, using a tissue-specific miRNA…”
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Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes
Published in Chemical science (Cambridge) (2018)“…Cysteine cathepsins normally function in the lysosomal degradation system where they are critical for the maintenance of cellular homeostasis and the MHC II…”
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Mineral, trace element, and toxic metal concentration in hair from dogs with idiopathic epilepsy compared to healthy controls
Published in Journal of veterinary internal medicine (01-05-2023)“…Background Altered trace element status is associated with epilepsy in humans and dogs with idiopathic epilepsy (IE). Objectives Compare hair element…”
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Puppyhood diet as a factor in the development of owner‐reported allergy/atopy skin signs in adult dogs in Finland
Published in Journal of veterinary internal medicine (01-09-2021)“…Background The increased prevalence of atopic dermatitis (AD) in dogs necessitates research in its disease etiology. Objectives To explore the association…”
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Copepod reproductive effort and oxidative status as responses to warming in the marine environment
Published in Ecology and evolution (01-02-2022)“…The marine ecosystems are under severe climate change‐induced stress globally. The Baltic Sea is especially vulnerable to ongoing changes, such as warming. The…”
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Novel Noncatalytic Role for Caspase-8 in Promoting Src-Mediated Adhesion and Erk Signaling in Neuroblastoma Cells
Published in Cancer research (Chicago, Ill.) (15-12-2007)“…Neuroblastomas are extremely aggressive, although heterogeneous, cancers with a poor prognosis upon metastasis. Some evidence has suggested a correlative…”
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Response to letter regarding “Puppyhood diet as a factor in the development of owner‐reported allergy/atopy skin signs in adult dogs in Finland”
Published in Journal of veterinary internal medicine (01-09-2022)“…In a world where our dogs suffer increasingly from noncommunicable diseases that are similar to those of humans (atopy, allergies, IBD, diabetes, certain…”
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Spatial Variation in Transcript and Protein Abundance of Atlantic Salmon during Feeding Migration in the Baltic Sea
Published in Environmental science & technology (02-12-2014)“…The fitness and reproductive output of fishes can be affected by environmental disturbances. In this study, transcriptomics and label-free proteomics were…”
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Migratory connectivity of two Baltic Sea salmon populations: retrospective analysis using stable isotopes of scales
Published in ICES journal of marine science (01-01-2014)“…Abstract Torniainen, J., Vuorinen, P. J., Jones, R. I., Keinänen, M., Palm, S., Vuori, K. A. M., and Kiljunen, M. 2014. Migratory connectivity of two Baltic…”
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atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (07-10-2008)“…Dock1 (also known as Dock180) is a prototypical member of a new family of atypical Rho GTPase activators. Genetic studies in Drosophila and Caenorhabditis…”
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