Search Results - "Vuori, Erkki"

Unintentional drowning: Role of medicinal drugs and alcohol by Pajunen, Tuulia, Vuori, Erkki, Vincenzi, Frank F, Lillsunde, Pirjo, Smith, Gordon, Lunetta, Philippe

“…Alcohol is a well-known risk factor in unintentional drownings. Whereas psychotropic drugs, like alcohol, may cause psychomotor impairment and affect…”
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Isotopic pattern and accurate mass determination in urine drug screening by liquid chromatography/time-of-flight mass spectrometry by Ojanperä, Suvi, Pelander, Anna, Pelzing, Matthias, Krebs, Ilmari, Vuori, Erkki, Ojanperä, Ilkka

“…An efficient method was developed for toxicological drug screening in urine by liquid chromatography coupled with electrospray ionization time‐of‐flight mass…”
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Epidemiology of alcohol-related unintentional drowning: is post-mortem ethanol production a real challenge? by Pajunen, Tuulia, Vuori, Erkki, Lunetta, Philippe

“…Post-mortem (PM) ethanol production may hamper the interpretation of blood alcohol concentration (BAC) in victims of drowning. Different exclusion criteria…”
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Screening for Basic Drugs in Hair of Drug Addicts by Liquid Chromatography/Time-of-Flight Mass Spectrometry by PELANDER, Anna, RISTIMAA, Johanna, RASANEN, Ilpo, VUORI, Erkki, OJANPERD, Ilkka

“…Hair analysis in forensic and clinical toxicology has been strongly focused on drugs of abuse, and comprehensive, drug class-independent screening methods…”
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An epidemic of fatal 3-methylfentanyl poisoning in Estonia by Ojanperä, Ilkka, Gergov, Merja, Liiv, Milana, Riikoja, Aime, Vuori, Erkki

“…An exceptional epidemic of poisonings due to the highly potent opioid designer drug 3-methylfentanyl (TMF) was revealed among Estonian drug users in 2005–2006…”
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Analysis of Street Drugs in Seized Material without Primary Reference Standards by Laks, Suvi, Pelander, Anna, Vuori, Erkki, Ali-Tolppa, Elisa, Sippola, Erkki, Ojanperä, Ilkka

“…A novel approach was used to analyze street drugs in seized material without primary reference standards. Identification was performed by liquid…”
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Infant Botulism Acquired from Household Dust Presenting as Sudden Infant Death Syndrome by Nevas, Mari, Lindström, Miia, Virtanen, Antti, Hielm, Sebastian, Kuusi, Markku, Arnon, Stephen S, Vuori, Erkki, Korkeala, Hannu

“…Clostridium botulinum type B was detected by multiplex PCR in the intestinal contents of a suddenly deceased 11-week-old infant and in vacuum cleaner dust from…”
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Alcohol and Benzodiazepines in Fatal Poisonings by Koski, Anna, Ojanperä, Ilkka, Vuori, Erkki

“…Background Postmortem forensic toxicology frequently finds alcohol both alone and in combination with drugs. Although benzodiazepines are generally considered…”
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Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood by Levo, Antti, Koski, Anna, Ojanperä, Ilkka, Vuori, Erkki, Sajantila, Antti

“…Tramadol is an opioid drug metabolised in phase I by cytochrome P450 (CYP) enzymes, of which CYP2D6 is mainly responsible for the O-demethylation of tramadol,…”
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CYP2D6 and CYP2C19 genotypes and amitriptyline metabolite ratios in a series of medicolegal autopsies by Koski, Anna, Sistonen, Johanna, Ojanperä, Ilkka, Gergov, Merja, Vuori, Erkki, Sajantila, Antti

“…In a series of 202 postmortem toxicology cases, the CYP2D6 and CYP2C19 genes were genotyped, and the concentrations of amitriptyline (AT) and six metabolites…”
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Death following ingestion of MDMA (ecstasy) and moclobemide by Vuori, Erkki, Henry, John A., Ojanperä, Ilkka, Nieminen, Raija, Savolainen, Taru, Wahlsten, Pia, Jäntti, Matti

“…ABSTRACT Four deaths following the ingestion of moclobemide and MDMA (‘ecstasy’) are described. The probable cause of death in each case was serotonin syndrome…”
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Performance of immunoassays in screening for opiates, cannabinoids and amphetamines in post-mortem blood by Hino, Yukiko, Ojanperä, Ilkka, Rasanen, Ilpo, Vuori, Erkki

“…Several immunoassay methods for screening of abused drugs in whole blood were evaluated in post-mortem forensic toxicology. Blood samples known to be positive…”
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Visual detection of cyanobacterial hepatotoxins by thin-layer chromatography and application to water analysis by Pelander, Anna, Ojanperä, Ilkka, Lahti, Kirsti, Niinivaara, Kauko, Vuori, Erkki

“…Visualization reactions for the thin-layer chromatographic (TLC) analysis of cyanobacterial hepatotoxins microcystins and nodularin were studied. Of the 17…”
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Profiles of pregabalin and gabapentin abuse by postmortem toxicology by Häkkinen, Margareeta, Vuori, Erkki, Kalso, Eija, Gergov, Merja, Ojanperä, Ilkka

“…Abstract Pregabalin (PRG) and gabapentin (GBP) are used in the treatment of neuropathic pain and epilepsy, and PRG also in generalized anxiety disorder. There…”
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Abuse liability of buprenorphine–naloxone tablets in untreated IV drug users by Alho, Hannu, Sinclair, David, Vuori, Erkki, Holopainen, Antti

“…Abstract Buprenorphine (Subutex® ) is widely abused in Finland. A combination of buprenorphine plus naloxone (Suboxone® ) has been available since late 2004,…”
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Fatal toxicity index of medicinal drugs based on a comprehensive toxicology database by Ojanperä, Ilkka, Kriikku, Pirkko, Vuori, Erkki

“…The fatal toxicity index (FTI) is the absolute number of fatal poisonings caused by a particular drug divided by its consumption figure. Consequently, it is a…”
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Wastewater analysis reveals regional variability in exposure to abused drugs and opioids in Finland by Vuori, Erkki, Happonen, Maiju, Gergov, Merja, Nenonen, Timo, Järvinen, Ari, Ketola, Raimo A., Vahala, Riku

“…Abused drug concentrations were determined in nine Finnish wastewater treatment plants (WWTPs), representing the metropolitan area, university cities and rural…”
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Comparison of fatal poisonings by prescription opioids by Häkkinen, Margareeta, Launiainen, Terhi, Vuori, Erkki, Ojanperä, Ilkka

“…Abstract There is a rising trend of fatal poisonings due to medicinal opioids in several countries. The present study evaluates the drug and alcohol findings…”
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Transdermal fentanyl in cachectic cancer patients by Heiskanen, Tarja, Mätzke, Sorjo, Haakana, Soile, Gergov, Merja, Vuori, Erkki, Kalso, Eija

“…Fentanyl is an opioid with high lipid solubility, suitable for intravenous, spinal, transmucosal and transdermal administration. The transdermal fentanyl patch…”
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Benzodiazepines and alcohol are associated with cases of fatal buprenorphine poisoning by Häkkinen, Margareeta, Launiainen, Terhi, Vuori, Erkki, Ojanperä, Ilkka

“…Background Although buprenorphine therapy has proved to be successful in opioid maintenance treatments, the drug is also widely abused in many countries by…”
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