Search Results - "Vuong, Mai T."
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A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein
Published in Emerging microbes & infections (01-12-2023)“…African swine fever virus is a complex DNA virus that causes high fatality in pigs and wild boar and has a great socio-economic impact. An attenuated genotype…”
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Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
Published in Cell (18-08-2022)“…The T cell receptor (TCR) expressed by T lymphocytes initiates protective immune responses to pathogens and tumors. To explore the structural basis of how TCR…”
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Structure of a fully assembled γδ T cell antigen receptor
Published in Nature (London) (17-10-2024)“…T cells in jawed vertebrates comprise two lineages, αβ T cells and γδ T cells, defined by the antigen receptors they express—that is, αβ and γδ T cell…”
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Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases
Published in Immunity (Cambridge, Mass.) (13-02-2024)“…Antibodies can block immune receptor engagement or trigger the receptor machinery to initiate signaling. We hypothesized that antibody agonists trigger…”
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Deep analysis of cellular transcriptomes - LongSAGE versus classic MPSS
Published in BMC genomics (24-09-2007)“…Deep transcriptome analysis will underpin a large fraction of post-genomic biology. 'Closed' technologies, such as microarray analysis, only detect the set of…”
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Differential remodeling of a T-cell transcriptome following CD8- versus CD3-induced signaling
Published in Cell research (01-06-2008)“…CD8 engagement with class I major histocompatibility antigens greatly enhances T-cell activation, but it is not clear how this is achieved. We address the…”
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Association of soluble CD89 levels with disease progression but not susceptibility in IgA nephropathy
Published in Kidney international (01-12-2010)“…The Fc-α receptor (FcαR/CD89) is involved in IgA complex formation and may affect the development of IgA nephropathy (IgAN). In this study, we tested the…”
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T Cell Receptors are Structures Capable of Initiating Signaling in the Absence of Large Conformational Rearrangements
Published in The Journal of biological chemistry (13-04-2012)“…Native and non-native ligands of the T cell receptor (TCR), including antibodies, have been proposed to induce signaling in T cells via intra- or intersubunit…”
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