Search Results - "Vuist, Ilona M"

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion by Vliet, Sandra J., Bay, Sylvie, Vuist, Ilona M., Kalay, Hakan, García‐Vallejo, Juan J., Leclerc, Claude, Kooyk, Yvette

“…The C‐type lectin MGL activates the ERK‐p90RSK‐CREB axis, which together with TLR2 signaling leads to enhanced secretion of IL‐10 and TNFα. DCs orchestrate…”
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Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain by Bloem, Karien, Vuist, Ilona M, van der Plas, Arend-Jan, Knippels, Léon M J, Garssen, Johan, García-Vallejo, Juan J, van Vliet, Sandra J, van Kooyk, Yvette

“…C-type lectins are innate receptors expressed on antigen-presenting cells that are involved in the recognition of glycosylated pathogens and…”
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The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model by van Hagen, Martijn, Piebes, Diewertje G E, de Leeuw, Wim C, Vuist, Ilona M, van Roon-Mom, Willeke M C, Moerland, Perry D, Verschure, Pernette J

“…Huntington's disease (HD) is a fatal neurodegenerative disorder caused by a CAG expansion in the Huntingtin (HTT) gene. Proteolytic cleavage of mutant…”
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Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells by Bloem, Karien, García-Vallejo, Juan J, Vuist, Ilona M, Cobb, Brian A, van Vliet, Sandra J, van Kooyk, Yvette

“…The zwitterionic capsular polysaccharide A (PSA) of Bacteroides fragilis is the first carbohydrate antigen described to be presented in major…”
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Exploring Kp,uu,BBB values smaller than unity in remoxipride: A physiologically-based CNS model approach highlighting brain metabolism in drugs with passive blood-brain barrier transport by Zhang, Mengxu, Vuist, Ilona M., Rottschäfer, Vivi, de Lange, Elizabeth CM

“…Kp,uu,BBB values are crucial indicators of drug distribution into the brain, representing the steady-state relationship between unbound concentrations in…”
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Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands by Marcelo, Filipa, Supekar, Nitin, Corzana, Francisco, van der Horst, Joost C., Vuist, Ilona M., Live, David, Boons, Geert-Jan P.H., Smith, David F., van Vliet, Sandra J.

“…The human macrophage galactose-type lectin (MGL) is a C-type lectin characterized by a unique specificity for terminal GalNAc residues present in the…”
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Cell-to-Cell Transcription Variability as Measured by Single-Molecule RNA FISH to Detect Epigenetic State Switching by Beckman, William, Vuist, Ilona M, Kempe, Hermannus, Verschure, Pernette J

“…Single-molecule RNA fluorescent in situ hybridization (smRNA FISH) allows for the visualization, localization, and quantification of RNA transcripts within…”
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Human T Cell Activation Results in Extracellular Signal-regulated Kinase (ERK)-Calcineurin-dependent Exposure of Tn Antigen on the Cell Surface and Binding of the Macrophage Galactose-type Lectin (MGL) by van Vliet, Sandra J., Vuist, Ilona M., Lenos, Kristiaan, Tefsen, Boris, Kalay, Hakan, García-Vallejo, Juan J., van Kooyk, Yvette

“…The C-type lectin macrophage galactose-type lectin (MGL) exerts an immunosuppressive role reflected by its interaction with terminal GalNAc moieties, such as…”
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DCIR interacts with ligands from both endogenous and pathogenic origin by Bloem, Karien, Vuist, Ilona M, van den Berk, Meike, Klaver, Elsenoor J, van Die, Irma, Knippels, Léon M.J, Garssen, Johan, García-Vallejo, Juan J, van Vliet, Sandra J, van Kooyk, Yvette

“…Highlights • We compared the glycan specificity of the DC-expressed CLRs: DCIR and DC-SIGN. • DCIR and DC-SIGN have overlapping glycan specificities. • Novel…”
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MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients by Lenos, Kristiaan, Goos, Jeroen A C M, Vuist, Ilona M, den Uil, Sjoerd H, Delis-van Diemen, Pien M, Belt, Eric J Th, Stockmann, Hein B A C, Bril, Herman, de Wit, Meike, Carvalho, Beatriz, Giblett, Susan, Pritchard, Catrin A, Meijer, Gerrit A, van Kooyk, Yvette, Fijneman, Remond J A, van Vliet, Sandra J

“…Colorectal cancer (CRC) is the third most prevalent cancer type worldwide with a mortality rate of approximately 50%. Elevated cell-surface expression of…”
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Ligand Binding and Signaling of Dendritic Cell Immunoreceptor by Bloem, Karien, Vuist, Ilona M, van der Plas, Arend-Jan, Knippels, Léon M. J, Garssen, Johan, García-Vallejo, Juan J, van Vliet, Sandra J, van Kooyk, Yvette

“…C-type lectins are innate receptors expressed on antigen-presenting cells that are involved in the recognition of glycosylated pathogens and…”
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