Search Results - "Vu Chi Truc"
-
1
The Effect of Additives on the Zinc Carbenoid-Mediated Cyclopropanation of a Dihydropyrrole
Published in Journal of organic chemistry (03-07-2014)“…The synthesis of a key intermediate in the preparation of oral antidiabetic drug Saxagliptin is discussed with an emphasis on the challenges posed by the…”
Get full text
Journal Article -
2
7-Oxabicyclo[2.2.1]heptyl carboxylic acids as thromboxane A2 antagonists: aza .omega.-chain analogs
Published in Journal of medicinal chemistry (01-09-1990)“…A novel bicyclic prostaglandin analogue, [1S-[1 alpha, 2 alpha (Z), 3 alpha, 4 alpha]]-7-[3-[[[(1-…”
Get full text
Journal Article -
3
Preparation of β‑hydroxy-α-amino Acid Using Recombinant d‑Threonine Aldolase
Published in Organic process research & development (18-09-2015)“…The chiral β-hydroxy-α-amino acid, (2R,3S)-2-amino-3-hydroxy-3-(pyridin-4-yl)-propanoic acid, is a key intermediate in the synthesis of the API…”
Get full text
Journal Article -
4
Development of a Two-Step, Enantioselective Synthesis of an Amino Alcohol Drug Candidate
Published in Organic process research & development (18-09-2015)“…The process development and large scale synthesis for the β-hydroxyamino amide 1 is described. The route evolved from a multistep sequence utilizing a…”
Get full text
Journal Article -
5
General syntheses of 6- and 7-carbomethoxy-trans-1-heteradecalins and 6- and 7-carbomethoxy-trans-2-heteradecalins
Published in Journal of organic chemistry (01-06-1986)Get full text
Journal Article -
6
Benzazepinone calcium channel blockers. II: Synthesis and structure-activity studies of 3-alkylbenzazepinones
Published in Journal of medicinal chemistry (1992)Get full text
Journal Article -
7
Benzazepinone calcium channel blockers. 3. Synthesis and structure-activity studies of 3-alkylbenzazepinones
Published in Journal of medicinal chemistry (01-02-1992)“…As part of a program aimed at identifying novel analogues of diltiazem, we developed several synthetic routes for 3-alkylbenzazepinones, both in racemic and…”
Get full text
Journal Article -
8
THE SYNTHESES OF 6- AND 7-CARBOMETHOXY-TRANS-1- AND 2-HETERADECALINS
Published 01-01-1985“…While alternate synthetic schemes are available for the preparations of some of the compounds belonging to the 6- and 7-carbomethoxy-trans-1- and…”
Get full text
Dissertation -
9
9,11-Epoxy-9-homoprosta-5-enoic acid analogs as thromboxane A2 receptor antagonists
Published in Journal of medicinal chemistry (01-06-1990)“…A novel bicyclic prostaglandin analogue, (1S)-[1 alpha, 2 alpha(Z),3 alpha(1E,3S*,4R*),4 alpha]-7-[3-(3-hydroxy-4-phenyl-1-pentenyl)-7-…”
Get full text
Journal Article