Search Results - "Vu, Tania"

Quantum dots for quantitative imaging: from single molecules to tissue by Vu, Tania Q., Lam, Wai Yan, Hatch, Ellen W., Lidke, Diane S.

“…Since their introduction to biological imaging, quantum dots (QDs) have progressed from a little known, but attractive, technology to one that has gained broad…”
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Overcoming clinical BCR-ABL1 compound mutant resistance with combined ponatinib and asciminib therapy by Eide, Christopher A, Brewer, Diana, Xie, Tao, Schultz, Anna Reister, Savage, Samantha L, Muratcioglu, Serena, Merz, Noah, Press, Richard D, O'Hare, Thomas, Jacob, Thomas, Vu, Tania Q, Tognon, Cristina E, Macey, Tara A, Kuriyan, John, Kalodimos, Charalampos G, Druker, Brian J

“…BCR-ABL1 compound mutations can lead to resistance to ABL1 inhibitors in chronic myeloid leukemia (CML), which could be targeted by combining the ATP-site…”
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Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques by Burwitz, Benjamin J., Wettengel, Jochen M., Mück-Häusl, Martin A., Ringelhan, Marc, Ko, Chunkyu, Festag, Marvin M., Hammond, Katherine B., Northrup, Mina, Bimber, Benjamin N., Jacob, Thomas, Reed, Jason S., Norris, Reed, Park, Byung, Moller-Tank, Sven, Esser, Knud, Greene, Justin M., Wu, Helen L., Abdulhaqq, Shaheed, Webb, Gabriela, Sutton, William F., Klug, Alex, Swanson, Tonya, Legasse, Alfred W., Vu, Tania Q., Asokan, Aravind, Haigwood, Nancy L., Protzer, Ulrike, Sacha, Jonah B.

“…Hepatitis B virus (HBV) is a major global health concern, and the development of curative therapeutics is urgently needed. Such efforts are impeded by the lack…”
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Kinetics of G-protein–coupled receptor endosomal trafficking pathways revealed by single quantum dots by Fichter, Katye M., Flajolet, Marc, Greengard, Paul, Vu, Tania Q.

“…G-protein–coupled receptors (GPCRs) are the largest protein superfamily in the human genome; they comprise 30% of current drug targets and regulate diverse…”
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Ligand-Bound Quantum Dot Probes for Studying the Molecular Scale Dynamics of Receptor Endocytic Trafficking in Live Cells by Rajan, Sujata Sundara, Liu, Hong Yan, Vu, Tania Q

“…Endocytic receptor trafficking is a complex, dynamic process underlying fundamental cell function. An integrated understanding of endocytosis at the level of…”
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Heterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot tracking by Vermehren-Schmaedick, Anke, Krueger, Wesley, Jacob, Thomas, Ramunno-Johnson, Damien, Balkowiec, Agnieszka, Lidke, Keith A, Vu, Tania Q

“…Accumulating evidence underscores the importance of ligand-receptor dynamics in shaping cellular signaling. In the nervous system, growth factor-activated Trk…”
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Molecular-Scale Dynamics of Long Range Retrograde Brain-Derived Neurotrophic Factor Transport Shaped by Cellular Spatial Context by Vermehren-Schmaedick, Anke, Olah, Mark J, Ramunno-Johnson, Damien, Lidke, Keith A, Cohen, Michael S, Vu, Tania Q

“…Retrograde neurotrophin (NT) transport is a specialized form of signal transduction used to conduct information from axons to the cell bodies of central and…”
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Multiplexed imaging reveals heterogeneity of PI3K/MAPK network signaling in breast lesions of known PIK3CA genotype by Jacob, Thomas, Gray, Joe W., Troxell, Megan, Vu, Tania Q.

“…Purpose Activating genetic changes in the phosphatidylinositol-3-kinase (PI3K) signaling pathway are found in over half of invasive breast cancers (IBCs)…”
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Nanotechnology research: applications in nutritional sciences by Srinivas, Pothur R, Philbert, Martin, Vu, Tania Q, Huang, Qingrong, Kokini, Josef L, Saltos, Etta, Saos, Etta, Chen, Hongda, Peterson, Charles M, Friedl, Karl E, McDade-Ngutter, Crystal, Hubbard, Van, Starke-Reed, Pamela, Miller, Nancy, Betz, Joseph M, Dwyer, Johanna, Milner, John, Ross, Sharon A

“…The tantalizing potential of nanotechnology is to fabricate and combine nanoscale approaches and building blocks to make useful tools and, ultimately,…”
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Quantum Dots Monitor TrkA Receptor Dynamics in the Interior of Neural PC12 Cells by Sundara Rajan, Sujata, Vu, Tania Q

“…Can quantum dots (QDs) serve as physiologically relevant receptor probes in the interior of cells? We directly visualize endocytosis, redistribution, and…”
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Peptide-Conjugated Quantum Dots Activate Neuronal Receptors and Initiate Downstream Signaling of Neurite Growth by Vu, Tania Q, Maddipati, Ravikanth, Blute, Todd A, Nehilla, Barrett J, Nusblat, Leora, Desai, Tejal A

“…Quantum dots (QDs) could serve as fluorescent scaffolds for effecting specific physiological and pharmacological responses in cells. Here, we conjugate the…”
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One-Step Melt Synthesis of Water-Soluble, Photoluminescent, Surface-Oxidized Silicon Nanoparticles for Cellular Imaging Applications by Manhat, Beth A, Brown, Anna L, Black, Labe A, Ross, J. B. Alexander, Fichter, Katye, Vu, Tania, Richman, Erik, Goforth, Andrea M

“…We have developed a versatile, one-step melt synthesis of water-soluble, highly emissive silicon nanoparticles using bifunctional, low-melting solids (such as…”
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Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting by Jacob, Thomas, Agarwal, Anupriya, Ramunno-Johnson, Damien, O’Hare, Thomas, Gönen, Mehmet, Tyner, Jeffrey W., Druker, Brian J., Vu, Tania Q.

“…Many important signaling and regulatory proteins are expressed at low abundance and are difficult to measure in single cells. We report a molecular imaging…”
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Quantitative analysis of multivesicular bodies (MVBs) in the hypoglossal nerve: Evidence that neurotrophic factors do not use MVBs for retrograde axonal transport by Altick, Amy L., Baryshnikova, Larisa M., Vu, Tania Q., von Bartheld, Christopher S.

“…Multivesicular bodies (MVBs) are defined by multiple internal vesicles enclosed within an outer, limiting membrane. MVBs have previously been quantified in…”
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Spatial Structure and Diffusive Dynamics from Single-Particle Trajectories Using Spline Analysis by Long, Brian R., Vu, Tania Q.

“…Single-particle tracking of biomolecular probes has provided a wealth of information about intracellular trafficking and the dynamics of proteins and lipids in…”
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Identification of Quantum Dot Bioconjugates and Cellular Protein Co-localization by Hybrid Gel Blotting by Liu, Hong Yan, Vu, Tania Q

“…New approaches are needed to address the interaction of nanoparticles and cellular proteins at the molecular level. We present a modification of PAGE…”
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Distinct extracellular matrix microenvironments of progenitor and carotid endothelial cells by Vartanian, Keri B., Kirkpatrick, Sean J., McCarty, Owen J. T., Vu, Tania Q., Hanson, Stephen R., Hinds, Monica T.

“…Endothelial cells (ECs) produce and maintain the local extracellular matrix (ECM), a critical function that contributes to EC and blood vessel health. This…”
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Quantum dot hybrid gel blotting: a technique for identifying quantum dot-protein/protein-protein interactions by Vu, Tania Q, Liu, Hong Yan

“…We describe an alternative to the molecular biology technique of polyacrylamide gel electrophoresis-based Western blotting and immunoprecipitation, which is an…”
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Single Particle Quantum Dot Imaging Achieves Ultrasensitive Detection Capabilities for Western Immunoblot Analysis by Scholl, Benjamin, Liu, Hong Yan, Long, Brian R, McCarty, Owen J. T, O’Hare, Thomas, Druker, Brian J, Vu, Tania Q

“…Substantially improved detection methods are needed to detect fractionated protein samples present at trace concentrations in complex, heterogeneous tissue and…”
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Microcontact printing of quantum dot bioconjugate arrays for localized capture and detection of biomolecules by Pattani, Varun P., Li, Chunfei, Desai, Tejal A., Vu, Tania Q.

“…The nanometer size scale of quantum dots (QDs) along with their unique luminescent properties offers great potential as photostable, color-metrically…”
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