Search Results - "Vu, B Joseph"

Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations by Soldner, Frank, Laganière, Josée, Cheng, Albert W., Hockemeyer, Dirk, Gao, Qing, Alagappan, Raaji, Khurana, Vikram, Golbe, Lawrence I., Myers, Richard H., Lindquist, Susan, Zhang, Lei, Guschin, Dmitry, Fong, Lauren K., Vu, B. Joseph, Meng, Xiangdong, Urnov, Fyodor D., Rebar, Edward J., Gregory, Philip D., Zhang, H. Steve, Jaenisch, Rudolf

“…Patient-specific induced pluripotent stem cells (iPSCs) derived from somatic cells provide a unique tool for the study of human disease, as well as a promising…”
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LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction by Sanders, Laurie H, Laganière, Josée, Cooper, Oliver, Mak, Sally K, Vu, B. Joseph, Huang, Y. Anne, Paschon, David E, Vangipuram, Malini, Sundararajan, Ramya, Urnov, Fyodor D, Langston, J. William, Gregory, Philip D, Zhang, H. Steve, Greenamyre, J. Timothy, Isacson, Ole, Schüle, Birgitt

“…Abstract Parkinson's disease associated mutations in leucine rich repeat kinase 2 ( LRRK2 ) impair mitochondrial function and increase the vulnerability of…”
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Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations by Soldner, Frank, Laganière, Josée, Cheng, Albert W., Hockemeyer, Dirk, Gao, Qing, Alagappan, Raaji, Khurana, Vikram, Golbe, Lawrence I., Myers, Richard H., Lindquist, Susan, Zhang, Lei, Guschin, Dmitry, Fong, Lauren K., Vu, B. Joseph, Meng, Xiangdong, Urnov, Fyodor D., Rebar, Edward J., Gregory, Philip D., Zhang, H. Steve, Jaenisch, Rudolf

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Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease by Zeitler, Bryan, Froelich, Steven, Marlen, Kimberly, Shivak, David A, Yu, Qi, Li, Davis, Pearl, Jocelynn R, Miller, Jeffrey C, Zhang, Lei, Paschon, David E, Hinkley, Sarah J, Ankoudinova, Irina, Lam, Stephen, Guschin, Dmitry, Kopan, Lexi, Cherone, Jennifer M, Nguyen, Hoang-Oanh B, Qiao, Guijuan, Ataei, Yasaman, Mendel, Matthew C, Amora, Rainier, Surosky, Richard, Laganiere, Josee, Vu, B Joseph, Narayanan, Anand, Sedaghat, Yalda, Tillack, Karsten, Thiede, Christina, Gärtner, Annette, Kwak, Seung, Bard, Jonathan, Mrzljak, Ladislav, Park, Larry, Heikkinen, Taneli, Lehtimäki, Kimmo K, Svedberg, Marie M, Häggkvist, Jenny, Tari, Lenke, Tóth, Miklós, Varrone, Andrea, Halldin, Christer, Kudwa, Andrea E, Ramboz, Sylvie, Day, Michelle, Kondapalli, Jyothisri, Surmeier, D James, Urnov, Fyodor D, Gregory, Philip D, Rebar, Edward J, Muñoz-Sanjuán, Ignacio, Zhang, H Steve

“…Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene ( HTT ), which…”
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