Search Results - "Vroegrijk, Irene O.C.M."

META060 protects against diet-induced obesity and insulin resistance in a high-fat–diet fed mouse by Vroegrijk, Irene O.C.M., M.Sc, van Diepen, Janna A., M.Sc, van den Berg, Sjoerd A.A., Ph.D, Romijn, Johannes A., M.D., Ph.D, Havekes, Louis M., Ph.D, van Dijk, Ko Willems, Ph.D, Darland, Gary, Ph.D, Konda, Veera, Ph.D, Tripp, Matthew L., Ph.D, Bland, Jeffrey S., Ph.D, Voshol, Peter J., Ph.D

“…Abstract Objective We investigated whether a reduced iso-α acid derived from an extract of Humulus lupulus L ., META060, had an effect on weight gain, body…”
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Pomegranate seed oil, a rich source of punicic acid, prevents diet-induced obesity and insulin resistance in mice by Vroegrijk, Irene O.C.M., van Diepen, Janna A., van den Berg, Sjoerd, Westbroek, Irene, Keizer, Hiskias, Gambelli, Luisa, Hontecillas, Raquel, Bassaganya-Riera, Josep, Zondag, Gerben C.M., Romijn, Johannes A., Havekes, Louis M., Voshol, Peter J.

“…Pomegranate seed oil has been shown to protect against diet induced obesity and insulin resistance. To characterize the metabolic effects of punicic acid on…”
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Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo by Fonager, Jannik, Pasini, Erica M, Braks, Joanna A M, Klop, Onny, Ramesar, Jai, Remarque, Edmond J, Vroegrijk, Irene O C M, van Duinen, Sjoerd G, Thomas, Alan W, Khan, Shahid M, Mann, Matthias, Kocken, Clemens H M, Janse, Chris J, Franke-Fayard, Blandine M D

“…Adherence of parasite-infected red blood cells (irbc) to the vascular endothelium of organs plays a key role in the pathogenesis of Plasmodium falciparum…”
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Increased β-Cell Mass by Islet Transplantation and PLAG1 Overexpression Causes Hyperinsulinemic Normoglycemia and Hepatic Insulin Resistance in Mice by DECLERCQ, Jeroen, KUMAR, Anujith, VERFAILFLE, Catherine M, VAN DIEPEN, Janna A, VROEGRIJK, Irene O. C. M, GYSEMANS, Conny, DI PIETRO, Caterina, VOSHOL, Peter J, MATHIEU, Chantal, ECTORS, Nadine, VAN DE VEN, Wim J. M

“…It is believed that an organism remains normoglycemic despite an increase in the beta-cell mass because of decreased insulin production by beta-cells on a…”
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CD36 is important for adipocyte recruitment and affects lipolysis by Vroegrijk, Irene O.C.M., Klinken, Jan Bert, Diepen, Janna A., den Berg, Sjoerd A.A., Febbraio, Maria, Steinbusch, Laura K.M., Glatz, Jan F.C., Havekes, Louis M., Voshol, Peter J., Rensen, Patrick C.N., Dijk, Ko Willems, Harmelen, Vanessa

“…Objective: The scavenger receptor CD36 facilitates the cellular uptake of long‐chain fatty acids. As CD36‐deficiency attenuates the development of high fat…”
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FcRγ‐chain deficiency reduces the development of diet‐induced obesity by van Beek, Lianne, Vroegrijk, Irene O.C.M., Katiraei, Saeed, Heemskerk, Mattijs M., van Dam, Andrea D., Kooijman, Sander, Rensen, Patrick C.N., Koning, Frits, Verbeek, J. Sjef, Willems van Dijk, Ko, van Harmelen, Vanessa

“…Objective Pathogenic immunoglobulins are produced during the development of obesity and contribute to the development of insulin resistance (IR). However, the…”
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F c R γ‐chain deficiency reduces the development of diet‐induced obesity by van Beek, Lianne, Vroegrijk, Irene O.C.M., Katiraei, Saeed, Heemskerk, Mattijs M., van Dam, Andrea D., Kooijman, Sander, Rensen, Patrick C.N., Koning, Frits, Verbeek, J. Sjef, Willems van Dijk, Ko, van Harmelen, Vanessa

“…Objective Pathogenic immunoglobulins are produced during the development of obesity and contribute to the development of insulin resistance (IR). However, the…”
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Absence of fatty acid transporter CD36 protects against Western-type diet-related cardiac dysfunction following pressure overload in mice by Steinbusch, Laura K M, Luiken, Joost J F P, Vlasblom, Ronald, Chabowski, Adrian, Hoebers, Nicole T H, Coumans, Will A, Vroegrijk, Irene O C M, Voshol, Peter J, Ouwens, D Margriet, Glatz, Jan F C, Diamant, Michaela

“…Cardiac patients often are obese and have hypertension, but in most studies these conditions are investigated separately. Here, we aimed at 1) elucidating the…”
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Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion[S] by van Diepen, Janna A., Stienstra, Rinke, Vroegrijk, Irene O. C.M., van den Berg, Sjoerd A.A., Salvatori, Daniela, Hooiveld, Guido J., Kersten, Sander, Tack, Cees J., Netea, Mihai G., Smit, Johannes W.A., Joosten, Leo A.B., Havekes, Louis M., van Dijk, Ko Willems, Rensen, Patrick C.N.

“…Caspase-1 is known to activate the proinflammatory cytokines IL-1β and IL-18. Additionally, it can cleave other substrates, including proteins involved in…”
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Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet by van Diepen, Janna A, Vroegrijk, Irene O C M, Berbée, Jimmy F P, Shoelson, Steven E, Romijn, Johannes A, Havekes, Louis M, Rensen, Patrick C N, Voshol, Peter J

“…Systemic inflammation is strongly involved in the pathophysiology of the metabolic syndrome, a cluster of metabolic risk factors that includes…”
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META060 activates omega‐3 fatty acid receptor GPR120, reduces weight gain, and increases insulin sensitivity in high‐fat diet fed mice by Konda, Veera R., Desai, Anuradha, Darland, Gary, Vroegrijk, Irene O.C.M., van Diepen, Janna A., Voshol, Peter J., Bland, Jeffrey S., Tripp, Matthew L.

“…Abstract only Long chain ω‐3 fatty acids exert anti‐inflammatory and insulin sensitizing effects through the activation of G protein‐coupled receptor 120…”
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PS8 - 44. FcR-γ-chain-/- mice are protected against diet-induced obesity and diet-induced insulin resistance by Vroegrijk, Irene O.C.M., van Harmelen, Vanessa, van den Berg, Sjoerd A.A., van Klinken, Jan Bert, Salvatori, Daniela C.F., Havekes, Louis M., Verbeek, Sjef J., van Dijk, Ko Willems

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