Search Results - "Vrijens, B"

Methods for Measuring, Enhancing, and Accounting for Medication Adherence in Clinical Trials by Vrijens, B, Urquhart, J

“…Adherence to rationally prescribed medications is essential for effective pharmacotherapy. However, widely variable adherence to protocol‐specified dosing…”
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Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF) by Hiligsmann, M., Cornelissen, D., Vrijens, B., Abrahamsen, B., Al-Daghri, N., Biver, E., Brandi, M.L., Bruyère, O., Burlet, N., Cooper, C., Cortet, B., Dennison, E., Diez-Perez, A., Gasparik, A., Grosso, A., Hadji, P., Halbout, P., Kanis, J.A., Kaufman, J.M., Laslop, A., Maggi, S., Rizzoli, R., Thomas, T., Tuzun, S., Vlaskovska, M., Reginster, J.Y.

“…Summary Many patients at increased risk of fractures do not take their medication appropriately, resulting in a substantial decrease in the benefits of drug…”
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Commentary on "A Framework for Quantifying the Influence of Adherence and Dose Individualization" by Urquhart, J, Vrijens, B

“…Drugs that provide long durations of action after a last‐taken dose are said to be “forgiving,” as they allow the patient a degree of latitude in the timing of…”
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ESPACOMP Medication Adherence Reporting Guidelines (EMERGE): a reactive-Delphi study protocol by Helmy, R, Zullig, L L, Dunbar-Jacob, J, Hughes, D A, Vrijens, B, Wilson, I B, De Geest, S

“…IntroductionMedication adherence is fundamental to achieving optimal patient outcomes. Reporting research on medication adherence suffers from some…”
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Patient adherence to prescribed antimicrobial drug dosing regimens by Vrijens, Bernard, Urquhart, John

“…The aim of this article is to review current knowledge about the clinical impact of patients' variable adherence to prescribed anti-infective drug dosing…”
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Effect of Adherence as Measured by MEMS, Ritonavir Boosting, and CYP3A5 Genotype on Atazanavir Pharmacokinetics in Treatment-Naive HIV-Infected Patients by Savic, R M, Barrail-Tran, A, Duval, X, Nembot, G, Panhard, X, Descamps, D, Verstuyft, C, Vrijens, B, Taburet, A-M, Goujard, C, Mentré, F

“…We investigated population pharmacokinetics and pharmacogenetics of ritonavir‐boosted atazanavir (ATV), using drug intake times exactly recorded by the…”
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Illustration of the Combined Effect of Patient’s Adherence and Individual Biological Characteristics on Blood Pressure by Tousset, E, Lowy, A, Ong, S.H, Vrijens, B

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A structural mean model to allow for noncompliance in a randomized trial comparing 2 active treatments by Fischer, Krista, Goetghebeur, Els, Vrijens, Bernard, White, Ian R

“…We propose a structural mean modeling approach to obtain compliance-adjusted estimates for treatment effects in a randomized-controlled trial comparing 2…”
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Effects on blood pressure and cardiovascular risk of variations in patients' adherence to prescribed antihypertensive drugs: role of duration of drug action by Lowy, A, Munk, V C, Ong, S H, Burnier, M, Vrijens, B, Tousset, E P, Urquhart, J

“…To determine the effects of imperfect adherence (i.e. occasionally missing prescribed doses), and the influence of rate of loss of antihypertensive effect…”
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Analysis and Interpretation of 24-h Blood Pressure Profiles: Appropriate Mathematical Models May Yield Deeper Understanding by Parati, Gianfranco, Vrijens, Bernard, Vincze, Gábor

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Psychological approaches during conscious sedation. Hypnosis versus stress reducing strategies: a prospective randomized study by Faymonville, E M, Mambourg, H P, Joris, J, Vrijens, B, Fissette, J, Albert, A, Lamy, M

“…Stress reducing strategies are useful in patients undergoing surgery. Hypnosis is also known to alleviate acute and chronic pain. We therefore compared the…”
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Relationships between osteoporosis medication adherence, surrogate marker outcomes and non-vertebral fracture incidence by Eastell, R, Vrijens, B, Cahall, D, Roux, C, Ringe, J, Garnero, P, Watts, N

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Risedronate dosing before breakfast compared with dosing later in the day in women with postmenopausal osteoporosis by Kendler, D. L, Ringe, J. D, Ste-Marie, L. -G, Vrijens, B, Taylor, E. B, Delmas, P. D

“…Summary Two studies in postmenopausal women with osteoporosis provide information about the efficacy and safety of dosing oral risedronate 5 mg daily at a time…”
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Effect of vaccination against Mycoplasma hyopneumoniae in pig herds with an all-in/all-out production system by Maes, D, Deluyker, H, Verdonck, M, Castryck, F, Miry, C, Vrijens, B, Verbeke, W, Viaene, J, de Kruif, A

“…A multi-site field study was conducted to evaluate an inactivated Mycoplasma hyopneumoniae (Mh) vaccine in 14 pig herds infected by Mh and practising an…”
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The impact of compliance in pharmacokinetic studies by Vrijens, B, Goetghebeur, E

“…In population pharmacokinetic (PK) studies, one observes just a few concentration measures spread out in time, on a sizable sample of the target population…”
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The impact of compliance in pharmacokinetic studies by Vrijens, B., Goetghebeur, E.

“…In population pharmacokinetic (PK) studies, one observes just a few concentration measures spread out in time, on a sizable sample of the target population…”
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Study of risedronate therapy in osteoporotic patients using both electronic monitoring of patient adherence and bone marker data by Miki, T, Nishizawa, Y, Mizunuma, H, Takahashi, N, Hagino, H, Yoh, K, Tango, T, Vrijens, B

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Non-vitamin K antagonist oral anticoagulants: considerations on once- vs. twice-daily regimens and their potential impact on medication adherence by Vrijens, Bernard, Heidbuchel, Hein

“…Suboptimal medication adherence is a widespread problem in ambulatory care of chronic diseases, with deviations in either direction from the prescribed dosing…”
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Major features of dose omissions in 87 ambulatory drug trials by Vrijens, B., Tousset, E., Gaillard, P., Meétry, J., Urquhart, J.

“…Background From clinical studies whose sponsors have concurred with entering their anonymized data into a common archive, we have just finished the assembly…”
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Adherence to Medications: Insights Arising from Studies on the Unreliable Link Between Prescribed and Actual Drug Dosing Histories by BLASCHKE, Terrence F, OSTERBERG, Lars, VRIJENS, Bernard, URQUHART, John

“…Satisfactory adherence to aptly prescribed medications is essential for good outcomes of patient care and reliable evaluation of competing modes of drug…”
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