Search Results - "Vrijbloed, Jan W."

A new protein curbs the hypertrophic effect of myostatin inhibition, adding remarkable endurance to motor performance in mice by Boido, Marina, Butenko, Olena, Filippo, Consuelo, Schellino, Roberta, Vrijbloed, Jan W, Fariello, Ruggero G, Vercelli, Alessandro

“…Current efforts to improve muscle performance are focused on muscle trophism via inhibition of the myostatin pathway: however they have been unsuccessful in…”
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Injection of a soluble fragment of neural agrin (NT-1654) considerably improves the muscle pathology caused by the disassembly of the neuromuscular junction by Hettwer, Stefan, Lin, Shuo, Kucsera, Stefan, Haubitz, Monika, Oliveri, Filippo, Fariello, Ruggero G, Ruegg, Markus A, Vrijbloed, Jan W

“…Treatment of neuromuscular diseases is still an unsolved problem. Evidence over the last years strongly indicates the involvement of malformation and…”
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Anti-HIV activity and resistance profile of the CXC chemokine receptor 4 antagonist POL3026 by Moncunill, Gemma, Armand-Ugón, Mercedes, Clotet-Codina, Imma, Pauls, Eduardo, Ballana, Ester, Llano, Anuska, Romagnoli, Barbara, Vrijbloed, Jan W, Gombert, Frank O, Clotet, Bonaventura, De Marco, Steve, Esté, José A

“…We have studied the mechanism of action of Arg(*)-Arg-Nal(2)-Cys(1x)-Tyr-Gln-Lys-(d-Pro)-Pro-Tyr-Arg-Cit-Cys(1x)-Arg-Gly-(d-Pro)(*) (POL3026), a novel specific…”
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Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis by Zerbe, Katja, Pylypenko, Olena, Vitali, Francesca, Zhang, Weiwen, Rouset, Severine, Heck, Markus, Vrijbloed, Jan W., Bischoff, Daniel, Bister, Bojan, Süssmuth, Roderich D., Pelzer, Stefan, Wohlleben, Wolfgang, Robinson, John A., Schlichting, Ilme

“…Gene-inactivation studies point to the involvement of OxyB in catalyzing the first oxidative phenol coupling reaction during glycopeptide antibiotic…”
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Synergistically Acting on Myostatin and Agrin Pathways Increases Neuromuscular Junction Stability and Endurance in Old Mice by Schellino, Roberta, Boido, Marina, Vrijbloed, Jan W, Fariello, Ruggero G, Vercelli, Alessandro

“…Sarcopenia is the primary cause of impaired motor performance in the elderly. The current prevailing approach to counteract such condition is increasing the…”
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Molecular, Biochemical, and Functional Characterization of a Nudix Hydrolase Protein That Stimulates the Activity of a Nicotinoprotein Alcohol Dehydrogenase by Kloosterman, Harm, Vrijbloed, Jan W, Dijkhuizen, Lubbert

“…The cytoplasmic coenzyme NAD + -dependent alcohol (methanol) dehydrogenase (MDH) employed by Bacillus methanolicus during growth on C 1 -C 4 primary alcohols…”
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Insertional Inactivation of Methylmalonyl Coenzyme A (CoA) Mutase and Isobutyryl-CoA Mutase Genes in Streptomyces cinnamonensis: Influence on Polyketide Antibiotic Biosynthesis by Vrijbloed, J W, Zerbe-Burkhardt, K, Ratnatilleke, A, Grubelnik-Leiser, A, Robinson, J A

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Using a β-Hairpin To Mimic an α-Helix: Cyclic Peptidomimetic Inhibitors of the p53-HDM2 Protein-Protein Interaction by Fasan, Rudi, Dias, Ricardo L. A., Moehle, Kerstin, Zerbe, Oliver, Vrijbloed, Jan W., Obrecht, Daniel, Robinson, John A.

“…Inhibition of crucial protein–protein interactions, for example, between the p53 tumor suppressor (red in structure) and HDM2, a protein overexpressed in tumor…”
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Properties and structure–activity studies of cyclic β-hairpin peptidomimetics based on the cationic antimicrobial peptide protegrin I by Robinson, John A., Shankaramma, Sasalu C., Jetter, Peter, Kienzl, Ursula, Schwendener, Reto A., Vrijbloed, Jan W., Obrecht, Daniel

“…[Display omitted] The properties and structure–activity relationships (SAR) of a macrocyclic analogue of porcine protegrin I (PG-I) have been investigated. The…”
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Investigation of de novo totally random biosequences, Part II: On the folding frequency in a totally random library of de novo proteins obtained by phage display by Chiarabelli, Cristiano, Vrijbloed, Jan W, De Lucrezia, Davide, Thomas, Richard M, Stano, Pasquale, Polticelli, Fabio, Ottone, Tiziana, Papa, Ester, Luisi, Pier Luigi

“…We present an investigation on theoretically possible protein structures which have not been selected by evolution and are, therefore, not present on our Earth…”
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Investigation of de novo totally random biosequences, Part I: A general method for in vitro selection of folded domains from a random polypeptide library displayed on phage by Chiarabelli, Cristiano, Vrijbloed, Jan W, Thomas, Richard M, Luisi, Pier Luigi

“…This paper reports the initial phase of a research aimed at investigating the folding frequency within a large library of polypeptides generated with a totally…”
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Macrocyclic Hairpin Mimetics of the Cationic Antimicrobial Peptide Protegrin I: A New Family of Broad-Spectrum Antibiotics by Shankaramma, Sasalu C., Athanassiou, Zafiria, Zerbe, Oliver, Moehle, Kerstin, Mouton, Carole, Bernardini, Francesca, Vrijbloed, Jan W., Obrecht, Daniel, Robinson, John A.

“…The problems associated with increasing antibiotic resistance have stimulated great interest in newly discovered families of naturally occurring cationic…”
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Analysis of Antibody A6 Binding to the Extracellular Interferon γ Receptor α-Chain by Alanine-Scanning Mutagenesis and Random Mutagenesis with Phage Display by Lang, Stefan, Xu, Jian, Stuart, Fiona, Thomas, Richard M, Vrijbloed, Jan W, Robinson, John A

“…The monoclonal antibody A6 binds a conformational epitope comprising mainly the CC‘ surface loop on the N-terminal fibronectin type-III domain of the…”
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Cloning and Sequencing of the Coenzyme B12-binding Domain of Isobutyryl-CoA Mutase from Streptomyces cinnamonensis, Reconstitution of Mutase Activity, and Characterization of the Recombinant Enzyme Produced inEscherichia coli by Ratnatilleke, Ananda, Vrijbloed, Jan W., Robinson, John A.

“…Isobutyryl-CoA mutase (ICM) catalyzes the reversible, coenzyme B12-dependent rearrangement of isobutyryl-CoA to n-butyryl-CoA, which is similar to, but…”
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Characterization and phylogeny of the pfp gene of Amycolatopsis methanolica encoding PPi-dependent phosphofructokinase by Alves, A M, Meijer, W G, Vrijbloed, J W, Dijkhuizen, L

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Towards Random Polypeptide Synthesis by Richard M. Thomas, Jan W. Vrijbloed, Pier-Luigi Luisi

“…Modern naturally occurring proteins have been produced by a lengthy selective evolutionary process. While, in general, they are all composed of the same 20…”
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Injection of a Soluble Fragment of Neural Agrin by Hettwer, Stefan, Lin, Shuo, Kucsera, Stefan, Haubitz, Monika, Oliveri, Filippo, Fariello, Ruggero G, Ruegg, Markus A, Vrijbloed, Jan W

“…Treatment of neuromuscular diseases is still an unsolved problem. Evidence over the last years strongly indicates the involvement of malformation and…”
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A family of macrocyclic antibiotics with a mixed peptide-peptoid beta-hairpin backbone conformation by Shankaramma, Sasalu C, Moehle, Kerstin, James, Sonya, Vrijbloed, Jan W, Obrecht, Daniel, Robinson, John A

“…Macrocyclic peptidomimetics having a mixed peptide-peptoid backbone have been synthesized and shown to possess antibiotic activity against gram-positive and…”
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Investigation ofde novo Totally Random Biosequences, Part I: A General Method forin vitro Selection of Folded Domains from a Random Polypeptide Library Displayed on Phage by Chiarabelli, Cristiano, Vrijbloed, Jan W., Thomas, Richard M., Luisi, Pier Luigi

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Investigation of de novo Totally Random Biosequences, Part I by Chiarabelli, Cristiano, Vrijbloed, Jan W., Thomas, Richard M., Luisi, Pier Luigi

“…This paper reports the initial phase of a research aimed at investigating the folding frequency within a large library of polypeptides generated with a totally…”
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