Search Results - "Vrieseling, Eline"
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Target-Induced Transcriptional Control of Dendritic Patterning and Connectivity in Motor Neurons by the ETS Gene Pea3
Published in Cell (29-12-2006)“…The apposition of axon terminals and dendrites is critical for the control of neuronal activation, but how distinct neuronal subpopulations establish selective…”
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2
A developmental switch in the response of DRG neurons to ETS transcription factor signaling
Published in PLoS biology (01-05-2005)“…Two ETS transcription factors of the Pea3 subfamily are induced in subpopulations of dorsal root ganglion (DRG) sensory and spinal motor neurons by…”
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3
Hunting cellular mechanisms underlying the spreading of misfolded protein pathology in the brain
Published in Neuropathology and applied neurobiology (01-02-2016)“…Cell to cell spread of misfolded proteins is a key mechanism in neurodegenerative diseases including Huntington's disease…”
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4
Transneuronal propagation of mutant huntingtin contributes to non–cell autonomous pathology in neurons
Published in Nature neuroscience (01-08-2014)“…Trans-neuronal transfer of pathogenic proteins has been demonstrated in multiple neurodegenerative diseases. Here the authors show in vitro and in a mouse…”
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5
Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition
Published in Nature (London) (11-06-2009)“…Spinal reflexes are mediated by synaptic connections between sensory afferents and motor neurons. The organization of these circuits shows several levels of…”
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6
Assembly of Motor Circuits in the Spinal Cord: Driven to Function by Genetic and Experience-Dependent Mechanisms
Published in Neuron (Cambridge, Mass.) (25-10-2007)“…Motor circuits in the spinal cord integrate information from various sensory and descending pathways to control appropriate motor behavior. Recent work has…”
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Transmission-selective muscle pathology induced by the active propagation of mutant huntingtin across the human neuromuscular synapse
Published in Frontiers in molecular neuroscience (03-01-2024)“…Neuron-to-neuron transmission of aggregation-prone, misfolded proteins may potentially explain the spatiotemporal accumulation of pathological lesions in the…”
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Synaptic and functional alterations in the development of mutant huntingtin expressing hiPSC-derived neurons
Published in Frontiers in molecular biosciences (19-07-2022)“…Huntington's disease (HD) is a monogenic disease that results in a combination of motor, psychiatric, and cognitive symptoms. It is caused by a CAG…”
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Rescue of oxytocin response and social behaviour in a mouse model of autism
Published in Nature (London) (13-08-2020)“…A fundamental challenge in developing treatments for autism spectrum disorders is the heterogeneity of the condition. More than one hundred genetic mutations…”
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Rescue of oxytocin response and social behavior in a rodent model of autism
Published in Nature (London) (01-08-2020)“…One of the most fundamental challenges in developing treatments for autism-spectrum disorders is the heterogeneity of the condition. More than one hundred…”
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Visualization of prion-like transfer in Huntington's disease models
Published in Biochimica et biophysica acta. Molecular basis of disease (01-03-2017)“…Most neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's disease are hallmarked by aggregate formation of disease-related proteins. In…”
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Author Correction: Transneuronal propagation of mutant huntingtin contributes to non–cell autonomous pathology in neurons
Published in Nature neuroscience (01-09-2018)“…In the version of this article initially published, the catalog numbers for BoNT A and B were given in the Methods section as T0195 and T5644; the correct…”
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CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations
Published in Stem cell reports (13-12-2016)“…In fragile X syndrome (FXS), CGG repeat expansion greater than 200 triplets is believed to trigger FMR1 gene silencing and disease etiology. However, FXS…”
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Review: Assembly of Motor Circuits in the Spinal Cord: Driven to Function by Genetic and Experience-Dependent Mechanisms
Published in Neuron (Cambridge, Mass.) (01-10-2007)Get full text
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15
Specificity of Sensory-Motor Connections Encoded by Sema3e-PlexinD1 Recognition
Published in Nature (London) (06-05-2009)“…Spinal reflexes are mediated by synaptic connections between sensory afferents and motor neurons 1 - 3 . The organization of these circuits exhibits several…”
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