Search Results - "Vries, R.G."

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids by Nantasanti, Sathidpak, Spee, Bart, Kruitwagen, Hedwig S., Chen, Chen, Geijsen, Niels, Oosterhoff, Loes A., van Wolferen, Monique E., Pelaez, Nicolas, Fieten, Hille, Wubbolts, Richard W., Grinwis, Guy C., Chan, Jefferson, Huch, Meritxell, Vries, Robert R.G., Clevers, Hans, de Bruin, Alain, Rothuizen, Jan, Penning, Louis C., Schotanus, Baukje A.

“…The recent development of 3D-liver stem cell cultures (hepatic organoids) opens up new avenues for gene and/or stem cell therapy to treat liver disease. To…”
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P16-26: Human kidney patient-derived organoids are a promising tool for modelling drug-induced nephrotoxicity and for assessing preclinical toxicity of immunotherapy by Merenda, A., Ehsani, N., Vries, R.G., Boj, S.F., Cantrill, C., Cabon, L., Gubler, M., Pott, J., Pourfarzad, F.

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Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver by Huch, Meritxell, Gehart, Helmuth, van Boxtel, Ruben, Hamer, Karien, Blokzijl, Francis, Verstegen, Monique M.A., Ellis, Ewa, van Wenum, Martien, Fuchs, Sabine A., de Ligt, Joep, van de Wetering, Marc, Sasaki, Nobuo, Boers, Susanne J., Kemperman, Hans, de Jonge, Jeroen, Ijzermans, Jan N.M., Nieuwenhuis, Edward E.S., Hoekstra, Ruurdtje, Strom, Stephen, Vries, Robert R.G., van der Laan, Luc J.W., Cuppen, Edwin, Clevers, Hans

“…Despite the enormous replication potential of the human liver, there are currently no culture systems available that sustain hepatocyte replication and/or…”
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P11-12 Human Liver patient-derived organoids are a promising tool to study drug-induced liver injury and drug metabolism for improved preclinical toxicology assessment by Merenda, A., Derksen, M., Kourula, S., Van Heerden, M., Frazer-Mendelewska, E., Lai, K.W., Boj, S.F., Snoeys, J., Vries, R.G., Pourfarzad, F.

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Intestinal organoids as in vitro model system to assess safety and ADME properties of compounds by Derksen, M., Kourula, S., Roos, J.L., Frazer-Mendelewska, E., Lai, K.W., Jonkers, S., Theuns, V., Verboven, P., Huybrechts, T., van Asten, S., Kunze, A., Jardi, F., Monshouwer, M., Vries, R.G., Boj, S.F., Snoeys, J., Pourfarzad, F.

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HUB Organoids™ improve pre-clinical toxicology, metabolism, and pharmacokinetic studies for drug discovery and development by Derksen, M., Kourula, S., Jacobs, F., Lee Roos, J., Van Heerden, M., Frazer-Mendelewska, E., Ramos, E., Lai, K.W., Jonkers, S., Theuns, V., Verboven, P., Huybrechts, T., van Asten, S., Kunze, A., Jardi, F., Monshouwer, M., Vries, R.G., Boj, S.F., Snoeys, J., Pourfarzad, F.

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Decentred comparative research: Context sensitive analysis of maternal health care by Wrede, Sirpa, Benoit, Cecilia, Bourgeault, Ivy Lynn, van Teijlingen, Edwin R., Sandall, Jane, De Vries, Raymond G.

“…Cross-national comparison is an important tool for health care research, but too often those who use this method fail to consider important inter-national…”
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Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients by Boj, Sylvia F, Vonk, Annelotte M, Statia, Marvin, Su, Jinyi, Vries, Robert R G, Beekman, Jeffrey M, Clevers, Hans

“…Recently-developed cystic fibrosis transmembrane conductance regulator (CFTR)-modulating drugs correct surface expression and/or function of the mutant CFTR…”
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The modern era of surgical trial designs: Perspectives of Parkinson's disease (PD) researchers by Freeman, T.B., Vawter, D.E., Gervais, K.G., Prehn, A.W., De Vries, R.G., Garrett, J.E., McIndoo, T.Q.

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L-malate in golden delicious apples as a possible parameter of acceptability by Gorin, N, van Belle, G, van der Vuurst de Vries, R G

“…Several batches of Golden Delicious apples from three geographical regions in the Netherlands were stored at 4 degrees C in a controlled atmosphere (CA) of 9%…”
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