Search Results - "Vrenken, H"
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Bidirectional trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-04-2015)“…Objective To investigate the coexistence of anterograde and retrograde trans-synaptic axonal degeneration, and to explore the relationship between selective…”
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2
Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis
Published in Brain (London, England : 1878) (22-06-2021)“…Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS, which can be compared across CNS regions, patients, and centres. In…”
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3
Optimizing parameter choice for FSL-Brain Extraction Tool (BET) on 3D T1 images in multiple sclerosis
Published in NeuroImage (Orlando, Fla.) (16-07-2012)“…Brain atrophy studies often use FSL-BET (Brain Extraction Tool) as the first step of image processing. Default BET does not always give satisfactory results on…”
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4
Mind the gap: from neurons to networks to outcomes in multiple sclerosis
Published in Nature reviews. Neurology (01-03-2021)“…MRI studies have provided valuable insights into the structure and function of neural networks, particularly in health and in classical neurodegenerative…”
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Clinical and MRI measures to identify non-acute MOG-antibody disease in adults
Published in Brain (London, England : 1878) (01-06-2023)“…Abstract MRI and clinical features of myelin oligodendrocyte glycoprotein (MOG)-antibody disease may overlap with those of other inflammatory demyelinating…”
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6
Predicting clinical progression in multiple sclerosis after 6 and 12 years
Published in European journal of neurology (01-06-2019)“…Background and purpose To predict disability and cognition in multiple sclerosis (MS) after 6 and 12 years, using early clinical and imaging measures. Methods…”
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Amnestic Mild Cognitive Impairment: Structural MR Imaging Findings Predictive of Conversion to Alzheimer Disease
Published in American journal of neuroradiology : AJNR (01-05-2008)“…Mild cognitive impairment (MCI) is considered by many to be a prodromal phase of Alzheimer disease (AD). We used voxel-based morphometry (VBM) to find out…”
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8
Time is myelin: early cortical myelin repair prevents atrophy and clinical progression in multiple sclerosis
Published in Brain (London, England : 1878) (04-04-2024)“…Cortical myelin loss and repair in multiple sclerosis (MS) have been explored in neuropathological studies, but the impact of these processes on…”
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9
Feasibility of detecting atrophy relevant for disability and cognition in multiple sclerosis using 3D-FLAIR
Published in Journal of neurology (01-11-2023)“…Background and objectives Disability and cognitive impairment are known to be related to brain atrophy in multiple sclerosis (MS), but 3D-T1 imaging required…”
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10
Reproducibility of Deep Gray Matter Atrophy Rate Measurement in a Large Multicenter Dataset
Published in American journal of neuroradiology : AJNR (01-01-2018)“…Precise in vivo measurement of deep GM volume change is a highly demanded prerequisite for an adequate evaluation of disease progression and new treatments…”
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11
Regional DTI differences in multiple sclerosis patients
Published in NeuroImage (Orlando, Fla.) (15-02-2009)“…Diffusion tensor imaging (DTI) measures have shown to be sensitive to white matter (WM) damage in multiple sclerosis (MS), not only inside focal lesions but…”
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12
Hippocampal atrophy rates in Alzheimer disease : Added value over whole brain volume measures
Published in Neurology (17-03-2009)“…To investigate the added value of hippocampal atrophy rates over whole brain volume measurements on MRI in patients with Alzheimer disease (AD), patients with…”
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13
Facing privacy in neuroimaging: removing facial features degrades performance of image analysis methods
Published in European radiology (01-02-2020)“…Background Recent studies have created awareness that facial features can be reconstructed from high-resolution MRI. Therefore, data sharing in neuroimaging…”
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14
What drives MRI-measured cortical atrophy in multiple sclerosis?
Published in Multiple sclerosis (01-09-2015)“…Background: Cortical atrophy, assessed with magnetic resonance imaging (MRI), is an important outcome measure in multiple sclerosis (MS) studies. However, the…”
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15
Comparing lesion segmentation methods in multiple sclerosis: Input from one manually delineated subject is sufficient for accurate lesion segmentation
Published in NeuroImage clinical (01-01-2019)“…•Lesion segmentation is an important tool in multiple sclerosis (MS) research.•Several automated methods exist, e.g., supervised, trained or deep…”
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16
Multimodal MRI study on the relation between WM integrity and connected GM atrophy and its effect on disability in early multiple sclerosis
Published in Journal of neurology (01-01-2024)“…Background Multiple sclerosis (MS) is characterized by pathology in white matter (WM) and atrophy of grey matter (GM), but it remains unclear how these…”
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17
Accumulation of cortical lesions in MS: relation with cognitive impairment
Published in Multiple sclerosis (01-06-2009)“…Background Gray matter (GM) lesions are frequently found in multiple sclerosis (MS) and their in-vivo detection has been improved using new magnetic resonance…”
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18
Recommendations to improve imaging and analysis of brain lesion load and atrophy in longitudinal studies of multiple sclerosis
Published in Journal of neurology (01-10-2013)“…Focal lesions and brain atrophy are the most extensively studied aspects of multiple sclerosis (MS), but the image acquisition and analysis techniques used can…”
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19
Temporal evolution of new T1-weighted hypo-intense lesions and central brain atrophy in patients with a first clinical demyelinating event treated with subcutaneous interferon β-1a
Published in Journal of neurology (01-04-2023)“…Objective Evaluate the effect of subcutaneous interferon β-1a (sc IFN β-1a) versus placebo on the evolution of T1-weighted MRI lesions and central brain…”
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20
White Matter Hyperintensity Volume and Cerebral Perfusion in Older Individuals with Hypertension Using Arterial Spin-Labeling
Published in American journal of neuroradiology : AJNR (01-10-2016)“…White matter hyperintensities of presumed vascular origin in elderly patients with hypertension may be part of a general cerebral perfusion deficit, involving…”
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