Search Results - "Vreijling, Jeroen P"
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Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis
Published in Acta neuropathologica communications (03-05-2018)“…The complement system is a key driver of neuroinflammation. Activation of complement by all pathways, results in the formation of the anaphylatoxin C5a and the…”
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Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals
Published in Diabetologia (01-04-2019)“…Aims/hypothesis Animal studies have indicated that disturbed diurnal rhythms of clock gene expression in adipose tissue can induce obesity and type 2 diabetes…”
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Whole-exome Sequencing Identifies SLC52A1 and ZNF106 Variants as Novel Genetic Risk Factors for (Early) Multiple-organ Failure in Acute Pancreatitis
Published in Annals of surgery (01-06-2022)“…The aim of this study was to identify genetic variants associated with early multiple organ failure (MOF) in acute pancreatitis. MOF is a life-threatening…”
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Cis D4Z4 repeat duplications associated with facioscapulohumeral muscular dystrophy type 2
Published in Human molecular genetics (15-10-2018)“…Abstract Facioscapulohumeral muscular dystrophy, known in genetic forms FSHD1 and FSHD2, is associated with D4Z4 repeat array chromatin relaxation and somatic…”
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Expression of complement components in the peripheral nervous system
Published in Human molecular genetics (01-02-2004)“…We have generated a SAGE (serial analysis of gene expression) library of normal sciatic nerve and found tags encoding for mRNAs of the complement system highly…”
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Type VI collagen mutations in Bethlem myopathy, an autosomal dominant myopathy with contractures
Published in Nature genetics (01-09-1996)“…Among the diverse family of collagens, the widely expressed microfibrillar type VI collagen is believed to play a role in bridging cells with the extracellular…”
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Transcriptional profile of the human peripheral nervous system by serial analysis of gene expression
Published in Genomics (San Diego, Calif.) (01-08-2003)“…The peripheral nerve contains both nonmyelinating and myelinating Schwann cells. The interactions between axons, surrounding myelin, and Schwann cells are…”
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