Search Results - "Vree, Marleen"

Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial by van der Ree, Meike H, MD, de Vree, J Marleen, MD, Stelma, Femke, MD, Willemse, Sophie, MD, van der Valk, Marc, MD, Rietdijk, Svend, MD, Molenkamp, Richard, PhD, Schinkel, Janke, MD, van Nuenen, Ad C, BSc, Beuers, Ulrich, Prof, Hadi, Salah, MD, Harbers, Marten, PhD, van der Veer, Eva, MSc, Liu, Kai, PhD, Grundy, John, PhD, Patick, Amy K, PhD, Pavlicek, Adam, PhD, Blem, Jacqueline, BSc, Huang, Michael, MD, Grint, Paul, MD, Neben, Steven, PhD, Gibson, Neil W, PhD, Kootstra, Neeltje A, PhD, Reesink, Hendrik W, Dr

“…Summary Background miR-122 is an important host factor for hepatitis C virus (HCV) replication. The aim of this study was to assess the safety and…”
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Tissue Distribution and Induction of Human Multidrug Resistant Protein 3 by Scheffer, George L, Kool, Marcel, de Haas, Marcel, de Vree, J Marleen L, Pijnenborg, Adriana C L M, Bosman, Diederik K, Oude Elferink, Ronald P J, van der Valk, Paul, Borst, Piet, Scheper, Rik J

“…The multidrug resistance protein (MRP) family consists of several members and, for some of these transporter proteins, distinct roles in multidrug resistance…”
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Delays in the diagnosis and treatment of tuberculosis patients in Vietnam: a cross-sectional study by Huong, Nguyen T, Vree, Marleen, Duong, Bui D, Khanh, Vu T, Loan, Vu T, Co, Nguyen V, Borgdorff, Martien W, Cobelens, Frank G

“…Treatment delay is an important indicator of access to tuberculosis diagnosis and treatment. Analyses of patient delay (i.e. time interval between onset of…”
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Mutations in the MDR3 Gene Cause Progressive Familial Intrahepatic Cholestasis by J. Marleen L. De Vree, Jacquemin, Emmanuel, Sturm, Ekkehard, Cresteil, Daniele, Bosma, Piter J., Aten, Jan, Deleuze, Jean-Francois, Desrochers, Marc, Burdelski, Martin, Bernard, Olivier, Ronald P. J. Oude Elferink, Hadchouel, Michelle

“…Class III multidrug resistance (MDR) P-glycoproteins (P-gp), mdr2 in mice and MDR3 in man, mediate the translocation of phosphatidylcholine across the…”
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Tuberculosis trends, Vietnam by Vree, Marleen, Bui, Duc Duong, Dinh, Ngoc Sy, Nguyen, Viet Co, Borgdorff, Martien W, Cobelens, Frank G J

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Immune phenotype and function of natural killer and T cells in chronic hepatitis C patients who received a single dose of anti‐MicroRNA‐122, RG‐101 by Stelma, Femke, van der Ree, Meike H., Sinnige, Marjan J., Brown, Anthony, Swadling, Leo, de Vree, J. Marleen L., Willemse, Sophie B., van der Valk, Marc, Grint, Paul, Neben, Steven, Klenerman, Paul, Barnes, Eleanor, Kootstra, Neeltje A., Reesink, Hendrik W.

“…MicroRNA‐122 is an important host factor for the hepatitis C virus (HCV). Treatment with RG‐101, an N‐acetylgalactosamine‐conjugated anti‐microRNA‐122…”
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Mortality and failure among tuberculosis patients who did not complete treatment in Vietnam: a cohort study by Vree, Marleen, Huong, Nguyen T, Duong, Bui D, Sy, Dinh N, Van, Le N, Co, Nguyen V, Cobelens, Frank G J, Borgdorff, Martien W

“…Tuberculosis treatment failure and death rates are low in the Western Pacific Region, including Vietnam. However, failure or death may also occur among…”
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High mortality during tuberculosis treatment does not indicate long diagnostic delays in Vietnam: a cohort study by Vree, Marleen, Huong, Nguyen T, Duong, Bui D, Co, Nguyen V, Sy, Dinh N, Cobelens, Frank G, Borgdorff, Martien W

“…Delay in tuberculosis diagnosis and treatment initiation may increase disease severity and mortality. In evaluations of tuberculosis control programmes high…”
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Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing by van der Ree, Meike H., Stelma, Femke, Willemse, Sophie B., Brown, Anthony, Swadling, Leo, van der Valk, Marc, Sinnige, Marjan J., van Nuenen, Ad C., de Vree, J. Marleen L., Klenerman, Paul, Barnes, Eleanor, Kootstra, Neeltje A., Reesink, Hendrik W.

“…With the introduction of DAA's, the majority of treated chronic hepatitis C patients (CHC) achieve a viral cure. The exact mechanisms by which the virus is…”
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Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial by de Vries, Elsemieke, Bolier, Ruth, Goet, Jorn, Parés, Albert, Verbeek, Jef, de Vree, Marleen, Drenth, Joost, van Erpecum, Karel, van Nieuwkerk, Karin, van der Heide, Frans, Mostafavi, Nahid, Helder, Jeltje, Ponsioen, Cyriel, Oude Elferink, Ronald, van Buuren, Henk, Beuers, Ulrich

“…Pruritus may seriously impair quality of life in patients with cholestatic diseases such as primary or secondary sclerosing cholangitis (PSC, SSC) and primary…”
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The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood by Jacquemin, Emmanuel, De Vree, J. Marleen L., Cresteil, Danièle, Sokal, Etienne M., Sturm, Ekkehard, Dumont, Micheline, Scheffer, George L., Paul, Marianne, Burdelski, Martin, Bosma, Piter J., Bernard, Olivier, Hadchouel, Michelle, Oude Elferink, Ronald P.J.

“…Background & Aims: We have specified the features of progressive familial intrahepatic cholestasis type 3 and investigated in 31 patients whether a defect of…”
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A Single Dose of Anti-MIR122 Oligonucleotide RG-101 Results in a less Activated Phenotype of NK Cells in Patients with Chronic Hepatitis C by Stelma, F, van der Ree, M.H, Sinnige, M.J, Marleen de Vree, J, Willemse, S.B, van der Valk, M, Neben, S, Grint, P, Kootstra, N.A, Reesink, H.W

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Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice by SMITH, A. J, DE VREE, J. M. L, OTTENHOFF, R, OUDE ELFERINK, R. P. J, SCHINKEL, A. H, BORST, P

“…Mice homozygous for a disruption in the Mdr2 gene (Mdr2 (-/-) mice) lack the Mdr2 P-glycoprotein (P-gp) in the canalicular membrane of the hepatocyte and are…”
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THU-100 Factors associated with the real-world biochemical response to fibrate therapy in primary biliary cholangitis by van Hooff, Maria C., de Veer, Rozanne C., Werner, Ellen, Beuers, Ulrich, Drenth, Joost P.H., Cuperus, Frans J.C., van Hoek, Bart, Veldt, Bart J., Klemt-Kropp, Michael, van Meer, Suzanne, Verdonk, Robert C., Flink, Hajo J., Vrolijk, Jan Maarten, Gevers, Tom J.G., Ponsioen, Cyriel Y., van Rooij, Janne, Kerbert-Dreteler, Marjo J., Nicolaas, Jerome Sint, De Vree, Marleen, de Vries, Elsemieke S., Friederich, Philip W., Tielemans, Merel M., Aktas, Huseyin, Hotho, Daphne M., de Wit, Ulrike, Kuyvenhoven, Johan P.H., Abraham, Sunje, Kuiper, Edith M.M., Schmittgens, Stephan, Alderslieste, Yasser A., Janssen, Harry L.A., Hansen, Bettina E., Erler, Nicole S., van der Meer, Adriaan J.

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Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis by De Vree, J.Marleen L., Ottenhoff, Roel, Bosma, Piter J., Smith, Alexander J., Aten, Jan, Oude Elferink, Ronald P.J.

“…Background & Aims: Patients with progressive familial intrahepatic cholestasis (PFIC) type 3 have a mutation in the MDR3 gene, encoding the hepatocanalicular…”
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MRP3, an Organic Anion Transporter Able to Transport Anti-Cancer Drugs by Kool, Marcel, van der Linden, Marcel, de Haas, Marcel, Scheffer, George L., J. Marleen L. De Vree, Smith, Alexander J., Jansen, Gerrit, Peters, Godefridus J., Ponne, Nico, Scheper, Rik J., Ronald P. J. Oude Elferink, Baas, Frank, Borst, Piet

“…The human multidrug-resistance protein (MRP) gene family contains at least six members: MRP1, encoding the multidrug-resistance protein; MRP2 or cMOAT,…”
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Impact of hepatic encephalopathy on liver transplant waiting list mortality in regions with different transplantation rates by Kerbert, Annarein J. C., Reverter, Enric, Verbruggen, Lara, Tieleman, Madelon, Navasa, Miguel, Mertens, Bart J. A., Rodríguez‐Tajes, Sergio, de Vree, Marleen, Metselaar, Herold J., Chiang, Fang W. T., Verspaget, Hein W., van Hoek, Bart, Bosch, Jaime, Coenraad, Minneke J.

“…Overt hepatic encephalopathy (OHE) negatively impacts the prognosis of liver transplant candidates. However, it is not taken into account in most prioritizing…”
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The role of phospholipids in bile formation: what can we learn from animals and human disease? by Elferink, Ronald Oude, Marleen, de Vree, Charles, Frijters, Groen, Albert

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Percutaneous Treatment of Peripheral Vascular Malformations in Children: Long-Term Clinical Outcome by van der Linden, Edwin, Otoide-Vree, Marleen, Pattynama, Peter M. T.

“…Purpose This study was designed to assess the rate of complications and clinical failure at 3 and 12 months after percutaneous treatment of vascular…”
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Survival and relapse rate of tuberculosis patients who successfully completed treatment in Vietnam by VREE, M, HUONG, N. T, DUONG, B. D, SY, D. N, VAN, L. N, HUNG, N. V, CO, N. V, BORGDORFF, M. W, COBELENS, F. G

“…SETTING: Reported tuberculosis (TB) cure rates are high in Vietnam with the 8-month short-course chemotherapy regimen. However, long-term treatment outcomes…”
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