Search Results - "Vrecer, F"
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1
Effect of crystal habit on the dissolution behaviour of simvastatin crystals and its relationship to crystallization solvent properties
Published in Pharmazie (01-05-2016)“…Simvastatin crystals, having same crystal structure but different types of habits and hence different intrinsic dissolution rate, were prepared by…”
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2
Overview of solidification techniques for self-emulsifying drug delivery systems from industrial perspective
Published in International journal of pharmaceutics (30-11-2017)“…[Display omitted] Self-emulsifying drug delivery systems (SEDDS) are lipid formulations that improve solubility and oral bioavailability of the incorporated…”
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3
Optimization of radial extrusion and pellet coating processes using PAT approaches
Published in European journal of pharmaceutical sciences (01-12-2023)“…FDA's initiative Pharmaceutical CGMPs for the 21st century opened the door for introduction of several risk based approaches in pharmaceutical industry. One…”
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4
Similarity of solid state structures of R- and S-isomers of clopidogrel hydrogensulphate salt
Published in Pharmazie (01-05-2010)“…The present study showed, that the crystal structures of R-isomer and the polymorphic form 1 of clopidrogrel hydrogensulphate S-isomer are very similar…”
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5
Solidification of carvedilol loaded SMEDDS by swirling fluidized bed pellet coating
Published in International journal of pharmaceutics (20-07-2019)“…[Display omitted] Self-(micro)emulsifying drug delivery systems (S(M)EDDS) have emerged as effective vehicles for enhancing bioavailability of poorly water…”
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6
Evaluation of solid carvedilol-loaded SMEDDS produced by the spray drying method and a study of related substances
Published in International journal of pharmaceutics (10-08-2021)“…[Display omitted] •Spray drying enables production of s-SMEDDS with high SMEDDS loading (up to 67% w/w).•Mixing time of dispersion before spray drying has…”
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7
Impact of the curing parameters on drug release from Eudragit RS and RL 30D coated pellets: Design of experiments
Published in Journal of drug delivery science and technology (01-12-2015)“…Polymethacrylate polymers are commonly used for the coating of prolonged-release pellets. Due to environmental and other concerns, aqueous latex dispersions…”
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8
Characterization of piroxicam crystal modifications
Published in International journal of pharmaceutics (30-04-2003)“…Piroxicam polymorphism was extensively studied in the past. The objective of the present work was to evaluate polymorphism of piroxicam once again and to…”
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Journal Article Conference Proceeding -
9
Application of experimental design methodology in development and optimization of drug release method
Published in International journal of pharmaceutics (03-03-2005)“…The aim of our research was to apply experimental design methodology in the development and optimization of drug release methods. Diclofenac sodium…”
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Journal Article Conference Proceeding -
10
The influence of gastric emptying kinetics on the drug release from enteric coated pellets in fasted state: An in vitro/in vivo correlation
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2012)“…Prediction of in vivo drug dissolution from enteric coated pellets on the basis of in vitro drug dissolution and gastric emptying of pellets under fasting…”
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11
Prediction of the in vivo performance of enteric coated pellets in the fasted state under selected biorelevant dissolution conditions
Published in European journal of pharmaceutical sciences (01-10-2014)“…[Display omitted] The purpose of this research was to predict the in vivo dissolution of lansoprazole from enteric coated pellets in the fasted state using a…”
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12
Characterization of physicochemical properties of hydroxypropyl methylcellulose (HPMC) type 2208 and their influence on prolonged drug release from matrix tablets
Published in Journal of pharmaceutical and biomedical analysis (01-07-2012)“…The key physicochemical properties of functional excipients should be identified, and the influence of their variability on the properties of the final dosage…”
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13
Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration
Published in International journal of pharmaceutics (04-06-2002)“…Enalaprilat is a typical angiotensin-converting enzyme inhibitor and is very poorly absorbed from the gastrointestinal tract. The aim of this study was to…”
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14
Statistical optimisation of diclofenac sustained release pellets coated with polymethacrylic films
Published in International journal of pharmaceutics (30-04-2003)“…The objective of the present study was to evaluate three formulation parameters for the application of polymethacrylic films from aqueous dispersions in order…”
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Journal Article Conference Proceeding -
15
The influence of HPMC viscosity as FRC parameter on the release of low soluble drug from hydrophylic matrix tablets
Published in Pharmaceutical development and technology (01-03-2013)“…The importance of functionality-related characteristics (FRC) of hydroxypropyl methylcellulose (HPMC) described in the pharmacopeia monograph can be evaluated…”
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16
Solubility of sodium diclofenac in different solvents
Published in Fluid phase equilibria (01-12-2007)“…The solubility of sodium diclofenac in several solvents such as acetone, ethyl acetate and dimethyl sulfoxide was studied, in the temperature range from 293.15…”
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Journal Article Conference Proceeding -
17
Optimization of melt pelletization in a high shear mixer
Published in International journal of pharmaceutics (03-11-2009)“…The effects of process conditions and binder content on the process yield and pellet characteristics of two formulations prepared by melt pelletization in a…”
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18
The effect of cores and coating dispersion composition on the mechanical and adhesion properties of hydroxypropyl methylcellulose films
Published in Pharmazie (01-08-2014)“…The influence of different additives on the mechanical properties of hydroxypropyl methylcellulose (HPMC) free films was studied using tensile testing. Free…”
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19
Interactions of biopolymers carrageenans with cationic drug doxazosin mesylate characterized by means of differential scanning calorimetry
Published in Pharmazie (01-07-2010)“…When ionic polymers (polyelectrolytes) are used as excipients in pharmaceutical formulations, the properties of oppositely charged drugs may be strongly…”
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20
Design of a drug delivery system with bimodal pH dependent release of a poorly soluble drug
Published in Pharmazie (01-06-2011)“…A delivery system which provides bimodal pH dependent release of poorly water soluble carvedilol in gastric and intestinal environment was designed…”
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