Search Results - "Vranic, Milica"
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Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism
Published in Scientific reports (29-06-2020)“…CRISPR/Cas9 has revolutionized the genome-editing field. So far, successful application in human adipose tissue has not been convincingly shown. We present a…”
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Subcutaneous adipose tissue dopamine D2 receptor is increased in prediabetes and T2D
Published in Endocrine (01-02-2024)“…Purpose To evaluate the dopaminergic signaling in human adipose tissue in the context of obesity and type 2 diabetes (T2D) and potential direct implications in…”
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3
CABLES1 expression is reduced in human subcutaneous adipose tissue in obesity and type 2 diabetes but may not directly impact adipocyte glucose and lipid metabolism
Published in Adipocyte (31-12-2023)“…Cdk5 and Abl enzyme substrate 1 (CABLES1) is a cell cycle regulator that has previously been identified as a candidate gene for obesity-related phenotypes, but…”
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4
ESR2 expression in subcutaneous adipose tissue is related to body fat distribution in women, and knockdown impairs preadipocyte differentiation
Published in Adipocyte (31-12-2022)“…Oestrogen receptor 2 (ESR2) expression has been shown to be higher in subcutaneous adipose tissue (SAT) from postmenopausal compared to premenopausal women…”
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Increased OCT3 Expression in Adipose Tissue With Aging: Implications for Catecholamine and Lipid Turnover and Insulin Resistance in Women
Published in Endocrinology (Philadelphia) (20-11-2023)“…Abstract Background Catecholamine-stimulated lipolysis is reduced with aging, which may promote adiposity and insulin resistance. Organic cation transporter 3…”
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FC028: Characterization of Adipocyte Size and Glucose Uptake in Adipose Tissue with Focus on Different Perirenal Fat Depots
Published in Nephrology, dialysis, transplantation (03-05-2022)“…Abstract BACKGROUND AND AIMS Previous studies have suggested that the anatomical location of adipose tissue, and the characteristics of the adipocytes…”
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7
Subcutaneous adipose tissue dopamine D2 receptor expression is increased in prediabetes and T2D
Published in Endocrine (2024)“…PurposeTo evaluate the dopaminergic signaling in human adipose tissue in the context of obesity and type 2 diabetes (T2D) and potential direct implications in…”
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Renal sinus adipose tissue: exploratory study of metabolic features and transcriptome compared with omental and subcutaneous adipose tissue
Published in Obesity (Silver Spring, Md.) (01-10-2024)“…Objective The objective was to study metabolic characteristics and transcriptome of renal sinus adipose tissue (RSAT) located around renal arteries and veins…”
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Role of Estrogen and Its Receptors in Adipose Tissue Glucose Metabolism in Pre- and Postmenopausal Women
Published in The journal of clinical endocrinology and metabolism (19-04-2022)“…Reduced estrogen levels in postmenopausal women predispose them to metabolic side effects, including insulin resistance and type 2 diabetes; however, the…”
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Effects of the second-generation antipsychotic drugs aripiprazole and olanzapine on human adipocyte differentiation
Published in Molecular and cellular endocrinology (05-02-2023)“…Second-generation antipsychotics (SGAs), used as the cornerstone treatment for schizophrenia and other mental disorders, can cause adverse metabolic effects…”
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CDKN2C expression in adipose tissue is reduced in type II diabetes and central obesity: impact on adipocyte differentiation and lipid storage?
Published in Translational research : the journal of laboratory and clinical medicine (01-04-2022)“…CDKN2C/p18 (Cyclin-Dependent Kinase Inhibitor 2C) is a cell growth regulator that controls cell cycle progression and has previously been associated with…”
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