Search Results - "Vrabie, Cozmina M"
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Synergistic androgenic effect of a petroleum product caused by the joint action of at least three different types of compounds
Published in Chemosphere (Oxford) (01-02-2016)“…In a previous study, we found a dose-dependent synergistic effect in recombinant yeast stably transfected with the human androgen receptor (AR), in response to…”
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Effect-Directed Assessment of the Bioaccumulation Potential and Chemical Nature of Ah Receptor Agonists in Crude and Refined Oils
Published in Environmental science & technology (07-02-2012)“…Recent studies have indicated that in addition to narcosis certain chemicals in crude oils and refined petroleum products may induce specific modes of action,…”
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Specific in vitro toxicity of crude and refined petroleum products. 1. Aryl hydrocarbon receptor - mediated responses
Published in Environmental toxicology and chemistry (01-09-2009)“…The present study is the first in a series reporting on in vitro toxic potencies of oils. The objective was to determine whether 11 crude oils and refined…”
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T-screen to quantify functional potentiating, antagonistic and thyroid hormone-like activities of poly halogenated aromatic hydrocarbons (PHAHs)
Published in Toxicology in vitro (01-06-2006)“…The present study investigates chemical thyroid hormone disruption at the level of thyroid hormone receptor (TR) functioning. To this end the (ant)agonistic…”
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Specific in vitro toxicity of crude and refined petroleum products: 3. Estrogenic responses in mammalian assays
Published in Environmental toxicology and chemistry (01-04-2011)“…Current petroleum risk assessment considers only narcosis as the mode of action, but several studies have demonstrated that oils contain compounds with…”
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Specific in vitro toxicity of crude and refined petroleum products: II. Estrogen (α and β) and androgen receptor-mediated responses in yeast assays
Published in Environmental toxicology and chemistry (01-07-2010)“…The present study is the second in a series aiming at a systematic inventory of specific toxic effects of oils. By employing a recombinant yeast stably…”
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