Search Results - "Voyvodic, Peter L."
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Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors
Published in Nature communications (12-04-2019)“…Cell-free transcription–translation systems have great potential for biosensing, yet the range of detectable chemicals is limited. Here we provide a workflow…”
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Metabolic perceptrons for neural computing in biological systems
Published in Nature communications (28-08-2019)“…Synthetic biological circuits are promising tools for developing sophisticated systems for medical, industrial, and environmental applications. So far, circuit…”
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Programmable receptors enable bacterial biosensors to detect pathological biomarkers in clinical samples
Published in Nature communications (01-09-2021)“…Bacterial biosensors, or bactosensors, are promising agents for medical and environmental diagnostics. However, the lack of scalable frameworks to…”
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Psilocybin Efficacy and Mechanisms of Action in Major Depressive Disorder: a Review
Published in Current Psychiatry Reports (01-10-2022)“…Purpose of the Review We aim to provide an overview of the current state of knowledge about the efficacy of psilocybin in the treatment of depression, as well…”
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Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance
Published in Scientific reports (12-08-2022)“…Cell-free biosensors are promising tools for medical diagnostics, yet their performance can be affected by matrix effects arising from the sample itself or…”
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Loss of Syndecan-1 Induces a Pro-inflammatory Phenotype in Endothelial Cells with a Dysregulated Response to Atheroprotective Flow
Published in The Journal of biological chemistry (04-04-2014)“…Fluid shear stresses are potent regulators of vascular homeostasis and powerful determinants of vascular disease progression. The glycocalyx is a layer of…”
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Molecular tension in syndecan-1 is regulated by extracellular mechanical cues and fluidic shear stress
Published in Biomaterials (01-08-2021)“…The endothelium plays a central role in regulating vascular homeostasis and is key in determining the response to materials implanted in the vascular system…”
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Microbially derived biosensors for diagnosis, monitoring and epidemiology
Published in Microbial biotechnology (01-09-2017)“…Summary Living cells have evolved to detect and process various signals and can self‐replicate, presenting an attractive platform for engineering scalable and…”
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A multichannel dampened flow system for studies on shear stress-mediated mechanotransduction
Published in Lab on a chip (21-09-2012)“…Shear stresses are powerful regulators of cellular function and potent mediators of the development of vascular disease. We have designed and optimized a…”
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PeroxiHUB: A Modular Cell-Free Biosensing Platform Using H2O2 as Signal Integrator
Published in ACS synthetic biology (19-08-2022)“…Cell-free systems have great potential for delivering robust, inexpensive, and field-deployable biosensors. Many cell-free biosensors rely on transcription…”
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Differentially Optimized Cell-Free Buffer Enables Robust Expression from Unprotected Linear DNA in Exonuclease-Deficient Extracts
Published in ACS synthetic biology (18-02-2022)“…The use of linear DNA templates in cell-free systems promises to accelerate the prototyping and engineering of synthetic gene circuits. A key challenge is that…”
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PeroxiHUB: A Modular Cell-Free Biosensing Platform Using H 2 O 2 as Signal Integrator
Published in ACS synthetic biology (19-08-2022)“…Cell-free systems have great potential for delivering robust, inexpensive, and field-deployable biosensors. Many cell-free biosensors rely on transcription…”
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Cell-free biosensors for biomedical applications
Published in Current opinion in biomedical engineering (01-03-2020)“…Recent years have witnessed a rapid increase of the use of cell-free systems for biosensor engineering. Building on the past decade of synthetic biology…”
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Differentially optimized cell-free buffer enables robust expression from unprotected linear DNA in exonuclease-deficient extracts
Published in ACS synthetic biology (01-12-2021)“…The use of linear DNA templates in cell-free systems promises to accelerate the prototyping and engineering of synthetic gene circuits. A key challenge is that…”
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