Search Results - "Voytas, Daniel"
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Precision genome engineering and agriculture: opportunities and regulatory challenges
Published in PLoS biology (01-06-2014)“…Plant agriculture is poised at a technological inflection point. Recent advances in genome engineering make it possible to precisely alter DNA sequences in…”
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2
Plant genome engineering with sequence-specific nucleases
Published in Annual review of plant biology (01-01-2013)“…Recent advances in genome engineering provide newfound control over a plant's genetic material. It is now possible for most bench scientists to alter DNA in…”
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3
TAL Effectors: Customizable Proteins for DNA Targeting
Published in Science (American Association for the Advancement of Science) (30-09-2011)“…Generating and applying new knowledge from the wealth of available genomic information is hindered, in part, by the difficulty of altering nucleotide sequences…”
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Generation and Inheritance of Targeted Mutations in Potato (Solanum tuberosum L.) Using the CRISPR/Cas System
Published in PloS one (14-12-2015)“…Genome editing using sequence-specific nucleases (SSNs) offers an alternative approach to conventional genetic engineering and an opportunity to extend the…”
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5
Attaining the promise of plant gene editing at scale
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-2021)“…Crop improvement relies heavily on genetic variation that arises spontaneously through mutation. Modern breeding methods are very adept at combining this…”
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Enabling plant synthetic biology through genome engineering
Published in Trends in biotechnology (Regular ed.) (01-02-2015)“…Highlights • Rewriting genomes will play an important role in plant synthetic biology. • Sequence-specific nucleases enable almost any DNA sequence change in…”
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7
Plant gene editing through de novo induction of meristems
Published in Nature biotechnology (01-01-2020)“…Plant gene editing is typically performed by delivering reagents such as Cas9 and single guide RNAs to explants in culture. Edited cells are then induced to…”
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Threshold-dependent repression of SPL gene expression by miR156/miR157 controls vegetative phase change in Arabidopsis thaliana
Published in PLoS genetics (19-04-2018)“…Vegetative phase change is regulated by a decrease in the abundance of the miRNAs, miR156 and miR157, and the resulting increase in the expression of their…”
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De novo domestication of wild tomato using genome editing
Published in Nature biotechnology (01-12-2018)“…A wild tomato species is domesticated by targeted CRISPR–Cas9 editing of just six genes. Breeding of crops over millennia for yield and productivity 1 has led…”
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High-frequency, precise modification of the tomato genome
Published in Genome Biology (06-11-2015)“…The use of homologous recombination to precisely modify plant genomes has been challenging, due to the lack of efficient methods for delivering DNA repair…”
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DNA Replicons for Plant Genome Engineering
Published in The Plant cell (01-01-2014)“…Sequence-specific nucleases enable facile editing of higher eukaryotic genomic DNA; however, targeted modification of plant genomes remains challenging due to…”
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A Single Transcript CRISPR-Cas9 System for Efficient Genome Editing in Plants
Published in Molecular plant (06-07-2016)“…The Streptococcus pyogenes CRISPR-Cas9 system effectively mediates RNA-guided DNA double-strand breaks and is used for genome editing in many different…”
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Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome
Published in PLoS genetics (01-08-2012)“…The zebrafish is a powerful experimental system for uncovering gene function in vertebrate organisms. Nevertheless, studies in the zebrafish have been limited…”
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14
Overcoming bottlenecks in plant gene editing
Published in Current opinion in plant biology (01-04-2020)“…Agriculture has reached a technological inflection point. The development of novel gene editing tools and methods for their delivery to plant cells promises to…”
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15
Efficient Virus-Mediated Genome Editing in Plants Using the CRISPR/Cas9 System
Published in Molecular plant (01-08-2015)Get full text
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16
A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation
Published in Plant physiology (Bethesda) (01-10-2015)“…The relative ease, speed, and biological scope of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated Protein9 (Cas9)-based…”
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Low‐gluten, nontransgenic wheat engineered with CRISPR/Cas9
Published in Plant biotechnology journal (01-04-2018)“…Summary Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins from wheat, barley and…”
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High‐efficiency gene targeting in hexaploid wheat using DNA replicons and CRISPR/Cas9
Published in The Plant journal : for cell and molecular biology (01-03-2017)“…Summary The ability to edit plant genomes through gene targeting (GT) requires efficient methods to deliver both sequence‐specific nucleases (SSNs) and repair…”
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A Multipurpose Toolkit to Enable Advanced Genome Engineering in Plants
Published in The Plant cell (01-06-2017)“…We report a comprehensive toolkit that enables targeted, specific modification of monocot and dicot genomes using a variety of genome engineering approaches…”
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Novel alleles of rice eIF4G generated by CRISPR/Cas9‐targeted mutagenesis confer resistance to Rice tungro spherical virus
Published in Plant biotechnology journal (01-11-2018)“…Summary Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro…”
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