Search Results - "Voswinkel, J."

Antithrombotic effects of hydroxychloroquine in primary antiphospholipid syndrome patients by Schmidt‐Tanguy, A., Voswinkel, J., Henrion, D., Subra, J. F., Loufrani, L., Rohmer, V., Ifrah, N., Belizna, C.

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Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: data from the European Group for Blood and Marrow Transplantation registry by Alchi, B, Jayne, D, Labopin, M, Kotova, O, Sergeevicheva, V, Alexander, T, Gualandi, F, Gruhn, B, Ouyang, J, Rzepecki, P, Held, G, Sampol, A, Voswinkel, J, Ljungman, P, Fassas, A, Badoglio, M, Saccardi, R, Farge, D

“…Objectives Patients with systemic lupus erythematosus (SLE) refractory to conventional immunosuppression suffer substantial morbidity and mortality due to…”
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B lymphocyte maturation in Wegener’s granulomatosis: a comparative analysis of VH genes from endonasal lesions by Voswinkel, J, Mueller, A, Kraemer, J A, Lamprecht, P, Herlyn, K, Holl-Ulrich, K, Feller, A C, Pitann, S, Gause, A, Gross, W L

“…Background: Anti-neutrophil cytoplasmic antibodies (ANCA) directed against proteinase 3 (PR3) are highly specific for Wegener’s granulomatosis (WG). Evidence…”
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Lack of efficacy of rituximab in Wegener’s granulomatosis with refractory granulomatous manifestations by Aries, P M, Hellmich, B, Voswinkel, J, Both, M, Nölle, B, Holl-Ulrich, K, Lamprecht, P, Gross, W L

“…Objective: To investigate the safety and efficacy of rituximab (RTX) in patients with refractory Wegener’s granulomatosis (WG). Patients and methods: Eight…”
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Effectiveness of TNF‐α blockade with infliximab in refractory Wegener's granulomatosis by Lamprecht, P., Voswinkel, J., Lilienthal, T., Nolle, B., Heller, M., Gross, W. L., Gause, A.

“…Objective. To study the effect of the chimeric monoclonal anti‐tumour necrosis factor α (TNF‐α) antibody infliximab in the induction of remission in six…”
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Is PR3-ANCA Formation Initiated in Wegener's Granulomatosis Lesions? Granulomas as Potential Lymphoid Tissue Maintaining Autoantibody Production by VOSWINKEL, J., MÜLLER, A., LAMPRECHT, P.

“…: In Wegener's granulomatosis (WG), antiproteinase 3 (PR3) autoantibodies (PR3‐ANCA) are crucial in the development of generalized vasculitis. Wegener's…”
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Single cell analysis of B lymphocytes from Wegener's granulomatosis: B cell receptors display affinity maturation within the granulomatous lesions by Voswinkel, J., Assmann, G., Held, G., Pitann, S., Gross, W. L., Holl‐Ulrich, K., Herlyn, K., Mueller, A.

“…Summary Increased amounts of anti‐neutrophil cytoplasm antibody (ANCA) directed against proteinase 3 (PR3) are a diagnostic and pathogenic hallmark of…”
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Rituximab induces remission in refractory HCV associated cryoglobulinaemic vasculitis by Lamprecht, P, Lerin-Lozano, C, Merz, H, Dennin, R H, Gause, A, Voswinkel, J, Peters, S O, Gutzeit, O, Arlt, A C, Solbach, W, Gross, W L

“…Objectives: To report the successful induction of remission with the monoclonal anti-CD20 antibody rituximab in a patient with hepatitis C virus (HCV)…”
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P-249 Myelodysplasic syndromes and vasculitis by Belizna, C, Ghali, A, Henrion, D, Hamidou, M, Lévesque, H, Voswinkel, J, Ifrah, N

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Prognosis of vasculitis associated myelodysplasia by Belizna, C, Subra, J.F, Henrion, D, Ghali, A, Renier, G, Royer, M, Corre, Y. Le, Martin, L, Voswinkel, J, Ifrah, N

“…Abstract Systemic and immune manifestations have been reported in patients with MDS. The correlation between immunological abnormalities and prognosis in…”
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Human mesenchymal stem cells provide protection against radiation-induced liver injury by antioxidative process, vasculature protection, hepatocyte differentiation and trophic effects by Francois, S, Mouiseddine, M, Allenet-Lepage, B, Voswinkel, J, Douay, L, Benderitter, M.M, Chapel, A

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Clinical and immunological response to mesenchymal stem cell (MSC) therapy first experiences in irradiation induced colitis by Voswinkel, J, Lataillade, J, Mothy, M, Gorin, N, Simon, J, Francois, S, Benderitter, M.M, Perrot, J, Chapel, A

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Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: data from the European Group for Blood and Marrow Transplantation registry by Alchi, B, Jayne, D, Labopin, M, Demin, A, Sergeevicheva, V, Alexander, T, Gualandi, F, Gruhn, B, Ouyang, J, Rzepecki, P, Held, G, Sampol, A, Voswinkel, J, Ljungman, P, Fassas, A, Badoglio, M, Saccardi, R, Farge, D

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Association of rheumatoid arthritis with Mdm2 SNP309 and genetic evidence for an allele-specific interaction between MDM2 and p53 P72R variants: a case control study by ASSMANN, G, VOSWINKEL, J, MUELLER, M, BITTENBRING, J, KOENIG, J, MENZEL, A, PFREUNDSCHUH, M, ROEMER, K, MELCHERS, I

“…This study examines two common, functional, single nucleotide polymorphisms (SNP) in the genes coding the human homolog of murine-double-minute-2 (MDM2) and…”
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Mesenchymal stem cells and rheumatism. State of the art by Voswinkel, J, Chapel, A

“…Mesenchymal stem cells (MSC) are multipotent. They are able to regenerate tissue damage and, in parallel, inhibit inflammation and fibrosis. As they are…”
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The p53 G72C and MDM2 T309G single nucleotide polymorphisms in patients with Wegener's granulomatosis by ASSMANN, G, WIECZOREK, S, WIBISONO, D, ROEMER, K, ARNING, L, VOSWINKEL, J

“…Wegener's granulomatosis (WG) is a rare disease with unknown aetiology, but there is evidence for a complex genetic background. The tumor suppressor p53 and…”
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A novel system to test for specificity of B-cell receptors from tissue of Wegener's granulomatosis patients by VOSWINKEL, J, KERKDIJK, A. J, MUELLER, A, ASSMANN, G, PFREUNDSCHUH, M, HELD, G

“…Wegener's granulomatosis (WG) is characterized by granulomatous inflammation of the respiratory tract and Anti Neutrophil Cytoplasmic Antibody…”
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Mesenchymal Stem/Stromal Cells: FROM EXPERIMENTAL RESEARCH TO CLINICAL TRIAL IN THE TREATMENT OF COMPLICATIONS OF RADIOTHERAPY BY STEM CELLS by Chapel, A., Semont, A., Linard, C., Mathieu, N., Squiban, C., Voswinkel, J., Rouard, H., Lataillade, J., Benderitter, M.M., Milliat, F., Gorin, N., Simon, J., Mothy, M.

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116 - Mesenchymal Stem/Stromal Cells: FROM EXPERIMENTAL RESEARCH TO CLINICAL TRIAL IN THE TREATMENT OF COMPLICATIONS OF RADIOTHERAPY BY STEM CELLS by Chapel, A., Semont, A., Linard, C., Mathieu, N., Squiban, C., Voswinkel, J., Rouard, H., Lataillade, J., Benderitter, M.M., Milliat, F., Gorin, N., Simon, J., Mothy, M.

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Clinical trial evaluating the efficacy of systemic mesenchymal stromal cell injections for the treatment of severe and chronic radiotherapy-induced abdomino-pelvic complications refractory to standard therapy by Chapel, A., Semont, A., Linard, C., Mathieu, N., Demarquay, C., Squiban, C., Voswinkel, J., Rouard, H., Gorin, N., Lataillade, J., Benderitter, M.M., Simon, J., Mothy, M.

“…The late adverse effects of pelvic radiotherapy concern 5 to 10% of patients, which could be life threatening. However, a clear medical consensus concerning…”
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