Search Results - "Vossler, David G"

Sustainability of seizure reduction and seizure control with adjunctive cenobamate: Post hoc analysis of a phase 3, open-label study by Vossler, David G, Rosenfeld, William E, Stern, Sean, Wade, Clarence T, Ferrari, Louis, Kerr, Wesley T, Wechsler, Robert

“…In this post hoc analysis of a subset of patients from a long-term, open-label phase 3 study, we assessed ≥50%, ≥75%, ≥90%, and 100% seizure reduction and…”
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FDA safety warning on the cardiac effects of lamotrigine: An advisory from the Ad Hoc ILAE/AES Task Force by French, Jacqueline A., Perucca, Emilio, Sander, Josemir W., Bergfeldt, Lennart, Baulac, Michel, Auerbach, David S., Keezer, Mark, Thijs, Roland D., Devinsky, Orrin, Vossler, David G., Welty, Timothy E.

“…Based on this activity, Lamictal could slow ventricular conduction (widen QRS) and induce proarrhythmia, including sudden death, in patients with structural…”
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Intellectual Disability and Epilepsy: The High Incidence and the Risks of Status Epilepticus and Sudden Death Require Improved Therapies by Vossler, David G.

“…Epidemiology of Developmental and Epileptic Encephalopathy and of Intellectual Disability and Epilepsy in Children Poke G, Stanley J, Scheffer IE, Sadleir LG…”
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Does SARS-CoV-2 Cause Seizures and Epilepsy in COVID-19 via Inflammation or by Direct Infection? by Vossler, David G.

“…Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis: A Retrospective Cohort Study Taquet M, Devinsky O, Cross JH, Harrison…”
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Remarkably High Efficacy of Cenobamate in Adults With Focal-Onset Seizures: A Double-Blind, Randomized, Placebo-Controlled Trial by Vossler, David G.

“…Safety and Efficacy of Adjunctive Cenobamate (YKP3089) in Patients With Uncontrolled Focal Seizures: A Multicentre, Double-Blind, Randomized,…”
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Ganaxolone: A New Treatment for CDKL5 Deficiency Disorder by Vossler, David G.

“…Safety and Efficacy of Ganaxolone in Patients With CDKL5 Deficiency Disorder: Results From the Double-Blind Phase of a Randomised, Placebo-Controlled, Phase 3…”
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Midazolam, Ketamine, and Propofol: While We Slept, Others Worked on Anesthetizing Infusions for Refractory Status Epilepticus by Vossler, David G.

“…Management of Refractory Status Epilepticus: An International Cohort Study (MORSE CODe) Analysis of Patients Managed in the ICU Chiu WT, Campozano V,…”
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Efficacy and safety of adjunctive lacosamide in the treatment of primary generalised tonic-clonic seizures: a double-blind, randomised, placebo-controlled trial by Vossler, David G, Knake, Susanne, O'Brien, Terence J, Watanabe, Masako, Brock, Melissa, Steiniger-Brach, Björn, Williams, Paulette, Roebling, Robert

“…ObjectiveTo evaluate efficacy and safety of lacosamide (up to 12 mg/kg/day or 400 mg/day) as adjunctive treatment for uncontrolled primary generalised…”
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Tiagabine in clinical practice: effects on seizure control and behavior by Vossler, David G, Morris, George L, Harden, Cynthia L, Montouris, Georgia, Faught, Edward, Kanner, Andres M, Fix, Aaron, French, Jacqueline A

“…Abstract Objective Preapproval randomized controlled trials of antiepileptic drugs provide data in limited patient groups. We assessed the side effect and…”
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Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits by Vossler, David G.

“…: Enzyme-inducing antiseizure medications (eiASMs) have been hypothesized to be associated with long-term risks of cardiovascular disease. : To quantify and…”
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Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open‐label safety study by Sperling, Michael R., Klein, Pavel, Aboumatar, Sami, Gelfand, Michael, Halford, Jonathan J., Krauss, Gregory L., Rosenfeld, William E., Vossler, David G., Wechsler, Robert, Borchert, Leona, Kamin, Marc

“…Objective During the development of cenobamate, an antiseizure medication (ASM) for focal seizures, three cases of drug reaction with eosinophilia and systemic…”
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Comparative Risk of Major Congenital Malformations With 8 Different Antiepileptic Drugs: A Prospective Cohort Study of the EURAP Registry by Vossler, David G.

“…Teratogenesis of 8 Antiepileptic Drugs in Multinational Experience Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Perucca E, Sabers A, Thomas SV, Vajda…”
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Diagnostic Yield and Treatment Changes After Genetic Testing of Adults With Epilepsy by Vossler, David G.

“…Multigene Panel Testing in a Large Cohort of Adults with Epilepsy: Diagnostic Yield and Clinically Actionable Genetic Findings McKnight D, Bristow SL, Truty…”
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Cutting-Edge Classification of Focal Cortical Dysplasia for Epilepsy Surgery by Vossler, David G.

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COVID-19 Incidence and Death Rate in Epilepsy: Too Early to Tell? by Vossler, David G.

“…Incidence and Case Fatality Rate of COVID-19 in Patients With Active Epilepsy Cabezudo-Garcia P, Ciano-Petersen NL, Mena-Vazquez N, et al. Neurology…”
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Antiepileptic drugs: Are generics as effective as brand name? by Vossler, David G

“…Antiepileptic drugs (AEDs) are the main treatment for seizures in people with epilepsy. The first AED, phenobarbital, was discovered in 1912 and the company…”
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Forecasting Seizure Storms Using Epilepsy Wristband Sensors by Vossler, David G.

“…Machine Learning From Wristband Sensor Data for Wearable, Noninvasive Seizure Forecasting Meisel C, El Atrache R, Jackson M, Schubach S, Ufongene C,…”
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The Nose Knows: Intranasal Midazolam To Treat Acute Seizures During Inpatient Epilepsy Monitoring by Vossler, David G.

“…Efficacy, Tolerability, and Safety of Concentrated Intranasal Midazolam Spray as Emergency Medication in Epilepsy Patients During Video-EEG Monitoring von…”
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Brain‐responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy by Geller, Eric B., Skarpaas, Tara L., Gross, Robert E., Goodman, Robert R., Barkley, Gregory L., Bazil, Carl W., Berg, Michael J., Bergey, Gregory K., Cash, Sydney S., Cole, Andrew J., Duckrow, Robert B., Edwards, Jonathan C., Eisenschenk, Stephan, Fessler, James, Fountain, Nathan B., Goldman, Alicia M., Gwinn, Ryder P., Heck, Christianne, Herekar, Aamar, Hirsch, Lawrence J., Jobst, Barbara C., King‐Stephens, David, Labar, Douglas R., Leiphart, James W., Marsh, W. Richard, Meador, Kimford J., Mizrahi, Eli M., Murro, Anthony M., Nair, Dileep R., Noe, Katherine H., Park, Yong D., Rutecki, Paul A., Salanova, Vicenta, Sheth, Raj D., Shields, Donald C., Skidmore, Christopher, Smith, Michael C., Spencer, David C., Srinivasan, Shraddha, Tatum, William, Van Ness, Paul C., Vossler, David G., Wharen, Robert E., Worrell, Gregory A., Yoshor, Daniel, Zimmerman, Richard S., Cicora, Kathy, Sun, Felice T., Morrell, Martha J.

“…Summary Objective Evaluate the seizure‐reduction response and safety of mesial temporal lobe (MTL) brain‐responsive stimulation in adults with medically…”
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Long-term safety and efficacy of adjunctive lacosamide in the treatment of generalized onset tonic-clonic seizures: An open-label extension trial by Vossler, David G, Farkas, Mark Kristof, Poverennova, Irina, Watanabe, Masako, Conrath, Peter, Dimova, Svetlana, McClung, Carrie, Roebling, Robert, Williams, Paulette, O'Brien, Terence J

“…This study was undertaken to assess long-term safety, tolerability, and efficacy of lacosamide (LCM) as adjunctive therapy for generalized onset tonic-clonic…”
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