Search Results - "Voss, Oliver H."

Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization by Akhter, Anwari, Caution, Kyle, Abu Khweek, Arwa, Tazi, Mia, Abdulrahman, Basant A., Abdelaziz, Dalia H.A., Voss, Oliver H., Doseff, Andrea I., Hassan, Hoda, Azad, Abul K., Schlesinger, Larry S., Wewers, Mark D., Gavrilin, Mikhail A., Amer, Amal O.

“…Inflammasomes are multiprotein complexes that include members of the NLR (nucleotide-binding domain leucine-rich repeat containing) family and caspase-1. Once…”
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Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock by Voss, Oliver H., Murakami, Yousuke, Pena, Mirna Y., Lee, Ha-Na, Tian, Linjie, Margulies, David H., Street, Jonathan M., Yuen, Peter S.T., Qi, Chen-Feng, Krzewski, Konrad, Coligan, John E.

“…Receptor CD300b is implicated in regulating the immune response to bacterial infection by an unknown mechanism. Here, we identified CD300b as a…”
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Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function by Cardenas, Horacio, Arango, Daniel, Nicholas, Courtney, Duarte, Silvia, Nuovo, Gerard J, He, Wei, Voss, Oliver H, Gonzalez-Mejia, M Elba, Guttridge, Denis C, Grotewold, Erich, Doseff, Andrea I

“…The increasing prevalence of inflammatory diseases and the adverse effects associated with the long-term use of current anti-inflammatory therapies prompt the…”
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Risk1, a Phosphatidylinositol 3-Kinase Effector, Promotes Rickettsia typhi Intracellular Survival by Voss, Oliver H, Gillespie, Joseph J, Lehman, Stephanie S, Rennoll, Sherri A, Beier-Sexton, Magda, Rahman, M Sayeedur, Azad, Abdu F

“…To establish a habitable intracellular niche, various pathogenic bacteria secrete effectors that target intracellular trafficking and modulate phosphoinositide…”
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Pathogenic, but Not Nonpathogenic, Rickettsia spp. Evade Inflammasome-Dependent IL-1 Responses To Establish an Intracytosolic Replication Niche by Voss, Oliver H, Cobb, Jennifer, Gaytan, Hodalis, Rivera Díaz, Natalia, Sanchez, Rigoberto, DeTolla, Louis, Rahman, M Sayeedur, Azad, Abdu F

“…species (spp.) are strict obligate intracellular bacteria, some of which are pathogenic in their mammalian host, including humans. One critical feature of…”
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Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis by Voss, Oliver H., Arango, Daniel, Tossey, Justin C., Villalona Calero, Miguel A., Doseff, Andrea I.

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selective killing of cancer cells underlines its anticancer potential. However, poor…”
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Binding of Caspase-3 Prodomain to Heat Shock Protein 27 Regulates Monocyte Apoptosis by Inhibiting Caspase-3 Proteolytic Activation by Voss, Oliver H., Batra, Sanjay, Kolattukudy, Sunny J., Gonzalez-Mejia, M. Elba, Smith, Jeffrey B., Doseff, Andrea I.

“…Caspase-3 is an essential executioner of apoptosis responsible for regulating many important cellular processes, among them the number of circulating…”
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Autophagy facilitates intracellular survival of pathogenic rickettsiae in macrophages via evasion of autophagosomal maturation and reduction of microbicidal pro-inflammatory IL-1 cytokine responses by Voss, Oliver H, Gaytan, Hodalis, Ullah, Saif, Sadik, Mohammad, Moin, Imran, Rahman, M Sayeedur, Azad, Abdu F

“…spp. are intracellular bacterial parasites of a wide range of arthropod and vertebrate hosts. Some rickettsiae are responsible for several severe human…”
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Emerging role of CD300 receptors in regulating myeloid cell efferocytosis by Voss, Oliver H, Tian, Linjie, Murakami, Yousuke, Coligan, John E, Krzewski, Konrad

“…Engulfment of apoptotic cells is predominantly executed by phagocytes via the recognition of "eat me" signals like phosphatidylserine (PS). Various PS-specific…”
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Rickettsia-host interaction: strategies of intracytosolic host colonization by Voss, Oliver H, Rahman, M Sayeedur

“…ABSTRACT Bacterial infection is a highly complex biological process involving a dynamic interaction between the invading microorganism and the host…”
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Apigenin Blocks Lipopolysaccharide-Induced Lethality In Vivo and Proinflammatory Cytokines Expression by Inactivating NF-κB through the Suppression of p65 Phosphorylation by Nicholas, Courtney, Batra, Sanjay, Vargo, Melissa A., Voss, Oliver H., Gavrilin, Mikhail A., Wewers, Mark D., Guttridge, Denis C., Grotewold, Erich, Doseff, Andrea I.

“…Abstract LPS stimulates monocytes/macrophages through the activation of signaling events that modulate the production of inflammatory cytokines. Apigenin, a…”
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Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling by Das, Amlan, Gopalakrishnan, Bhavani, Voss, Oliver H., Doseff, Andrea I., Villamena, Frederick A.

“…Oxidative stress is the main etiological factor behind the pathogenesis of various diseases including inflammation, cancer, cardiovascular and…”
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Apigenin-induced-apoptosis is mediated by the activation of PKCδ and caspases in leukemia cells by Vargo, Melissa A., Voss, Oliver H., Poustka, Frantisek, Cardounel, Arturo J., Grotewold, Erich, Doseff, Andrea I.

“…Apigenin, a flavone abundantly found in fruits and vegetables, exhibits antiproliferative, anti-inflammatory, and antimetastatic activities through poorly…”
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Distinct contribution of protein kinase Cδ and protein kinase Cε in the lifespan and immune response of human blood monocyte subpopulations by Malavez, Yadira, Voss, Oliver H., Gonzalez‐Mejia, Martha Elba, Parihar, Arti, Doseff, Andrea I.

“…Summary Monocytes, key components of the immune system, are a heterogeneous population comprised of classical monocytes (CD16−) and non‐classical monocytes…”
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The small heat shock protein 27 is a key regulator of CD8+ CD57+ lymphocyte survival by Wood, Karen L, Voss, Oliver H, Huang, Qin, Parihar, Arti, Mehta, Neeraj, Batra, Sanjay, Doseff, Andrea I

“…Differences in CD8(+)CD57(-) and CD8(+)CD57(+) lymphocyte lifespan have been documented. Lower numbers and shorter lifespan are characteristic of CD8(+)CD57(+)…”
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LPS-induced interaction between Cd300b/DAP12 and TLR4/CD14 results in the amplification of inflammation and increased mortality from sepsis by Voss, Oliver H., Coligan, John E.

“…Abstract LPS, present in gram-negative bacteria membranes, causes a strong immune cell activation following detection by TLR4, which initiates a…”
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Lipopolysaccharide-induced CD300b receptor binding to Toll-like Receptor 4 alters signaling to drive cytokine responses that enhance septic shock by Voss, Oliver H., Krzewski, Konrad, Coligan, John E.

“…Abstract LPS, present in gram-negative bacteria membranes, causes strong immune responses following detection by TLR4 on immune cells. Excess immune cell…”
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Distinct contribution of protein kinase C[delta] and protein kinase C[epsi] in the lifespan and immune response of human blood monocyte subpopulations by Malavez, Yadira, Voss, Oliver H, Gonzalez-Mejia, Martha Elba, Parihar, Arti, Doseff, Andrea I

“…Summary Monocytes, key components of the immune system, are a heterogeneous population comprised of classical monocytes (CD16-) and non-classical monocytes…”
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Lipopolysaccharide-induced binding of receptor CD300b to Toll-like receptor 4 alters signaling to drive lethal cytokine responses that enhance septic shock by Voss, Oliver H., Murakami, Yousuke, Pena, Mirna Y., Lee, Ha-Na, Tian, Linjie, Margulies, David H., Street, Jonathan M., Yuen, Peter S. T., Qi, Chen-Feng, Krzewski, Konrad, Coligan, John E.

“…Receptor CD300b is implicated in regulating the immune response to bacterial infection by an unknown mechanism. Here, we identified CD300b as an…”
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Regulation of Monocyte Apoptosis by the Protein Kinase Cδ-dependent Phosphorylation of Caspase-3 by Voss, Oliver H., Kim, Sunghan, Wewers, Mark D., Doseff, Andrea I.

“…Monocytes are central components of the innate immune response and normally circulate for a short period of time before undergoing spontaneous apoptosis…”
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