Search Results - "Voss, Jorine"

Oncogenic Properties of Apoptotic Tumor Cells in Aggressive B Cell Lymphoma by Ford, Catriona A., Petrova, Sofia, Pound, John D., Voss, Jorine J.L.P., Melville, Lynsey, Paterson, Margaret, Farnworth, Sarah L., Gallimore, Awen M., Cuff, Simone, Wheadon, Helen, Dobbin, Edwina, Ogden, Carol Anne, Dumitriu, Ingrid E., Dunbar, Donald R., Murray, Paul G., Ruckerl, Dominik, Allen, Judith E., Hume, David A., van Rooijen, Nico, Goodlad, John R., Freeman, Tom C., Gregory, Christopher D.

“…Cells undergoing apoptosis are known to modulate their tissue microenvironments. By acting on phagocytes, notably macrophages, apoptotic cells inhibit…”
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Macrocyclic Inhibitors of HGF-Activating Serine Proteases Overcome Resistance to Receptor Tyrosine Kinase Inhibitors and Block Lung Cancer Progression by Damalanka, Vishnu C, Voss, Jorine J. L. P, Mahoney, Matthew W, Primeau, Tina, Li, Shunqiang, Klampfer, Lidija, Janetka, James W

“…Hepatocyte growth factor (HGF), the ligand for the MET receptor tyrosine kinase, is a tumor-promoting factor that is abundant in the tumor microenvironment…”
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Peritubular Macrophages Are Recruited to the Testis of Peripubertal Rats After Mono-(2-Ethylhexyl) Phthalate Exposure and Is Associated With Increases in the Numbers of Spermatogonia by Gillette, Ross, Tiwary, Richa, Voss, Jorine J L P, Hewage, Shavini N, Richburg, John H

“…Abstract Peripubertal exposure of male rodents to the phthalate metabolite mono-(2-ethylhexyl) phthalate (MEHP) causes testicular inflammation, spermatocyte…”
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Modulation of macrophage antitumor potential by apoptotic lymphoma cells by Voss, Jorine J L P, Ford, Catriona A, Petrova, Sofia, Melville, Lynsey, Paterson, Margaret, Pound, John D, Holland, Pam, Giotti, Bruno, Freeman, Tom C, Gregory, Christopher D

“…In aggressive non-Hodgkin’s lymphoma (NHL), constitutive apoptosis of a proportion of the tumor cell population can promote net tumor growth. This is…”
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MEHP-induced rat testicular inflammation does not exacerbate germ cell apoptosis by Voss, Jorine J L P, Stermer, Angela R, Ghaffari, Rashin, Tiwary, Richa, Richburg, John H

“…The testis is an organ that maintains an immune suppressive environment. We previously revealed that exposure of pre-pubertal rats to an acute dose of a…”
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Microenvironmental Effects of Cell Death in Malignant Disease by Gregory, Christopher D, Ford, Catriona A, Voss, Jorine J L P

“…Although apoptosis is well recognized as a cell death program with clear anticancer roles, accumulating evidence linking apoptosis with tissue repair and…”
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Mono-(2-ethylhexyl) phthalate-induced Sertoli cell injury stimulates the production of pro-inflammatory cytokines in Fischer 344 rats by Stermer, Angela R., Murphy, Caitlin J., Ghaffari, Rashin, Di Bona, Kristin R., Voss, Jorine J., Richburg, John H.

“…•Germ cell apoptosis itself does not instigate macrophage infiltration into the testis.•MCP-1, IL-1α and IL-6 mRNA expression is increased in the seminiferous…”
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Economic impact of bladder cancer (BC) in the United States (US) by Clark, Otavio, Sarmento, Tulio, Eccleston, Anthony, Brinkmann, Julia, Picoli, Renato, Daliparthi, Vamsi, Voss, Jorine, Chandrasekar, Sanjana, Thompson, Allison, Chang, Jane

“…479 Background: Incidence and mortality for BC has changed very little over the past 20 years. Approximately 40% of patients with high-risk non-muscle invasive…”
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Abstract PO040: Protease inhibitors of HGF activation prevent HGF-dependent tumor progression and overcome resistance to anti-cancer therapy by Voss, Jorine J.L.P., Damalanka, Vishnu, Mahoney, Matthew, Klampfer, Lidija, Janetka, James W.

“…Abstract Overproduction of Hepatocyte Growth Factor (HGF) in the tumor microenvironment by tumor-associated fibroblasts or cancer cells is associated with poor…”
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A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells by Mahoney, Matthew, Damalanka, Vishnu C., Tartell, Michael A., Chung, Dong hee, Lourenço, André Luiz, Pwee, Dustin, Bridwell, Anne E. Mayer, Hoffmann, Markus, Voss, Jorine, Karmakar, Partha, Azouz, Nurit P., Klingler, Andrea M., Rothlauf, Paul W., Thompson, Cassandra E., Lee, Melody, Klampfer, Lidija, Stallings, Christina L., Rothenberg, Marc E., Pöhlmann, Stefan, Whelan, Sean P. J., O’Donoghue, Anthony J., Craik, Charles S., Janetka, James W.

“…The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug discovery. This protease activates the Spike protein of severe…”
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Mono-(2-ethylhexyl) phthalate (MEHP)-induced neutrophil and macrophage infiltration into the testicular interstitium of peripubertal rats does not exacerbate MEHP-induced germ cell apoptosis by Voss, Jorine J. L. P., Stermer, Angela R., Ghaffari, Rashin, Tiwary, Richa, Richburg, John H.

“…Abstract The testis is an immune-privileged organ that maintains an immune suppressive environment. We have previously shown that exposure of postnatal day…”
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Economic Impact of Bladder Cancer in the USA by Clark, Otavio, Sarmento, Tulio, Eccleston, Anthony, Brinkmann, Julia, Picoli, Renato, Daliparthi, Vamsi, Voss, Jorine, Chandrasekar, Sanjana, Thompson, Allison, Chang, Jane

“…Introduction Incidence and mortality for bladder cancer has changed very little over the past 20 years. Approximately 40% of patients with high-risk nonmuscle…”
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Mono-(2-ethylhexyl) phthalate-induced Sertoli cell injury stimulates the production of pro-inflammatory cytokines in Fisher 344 rats by Stermer, Angela R., Murphy, Caitlin J., Ghaffari, Rashin, Di Bona, Kristin R., Voss, Jorine J., Richburg, John H.

“…Exposure of rodents to the Sertoli cell (SC) toxicant mono-(2-ethylhexyl) phthalate (MEHP) has been reported to trigger an infiltration of macrophages into the…”
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