Search Results - "Voss, Felizia K"
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Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC
Published in Science (American Association for the Advancement of Science) (09-05-2014)“…Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion…”
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Journal Article -
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Inactivation and Anion Selectivity of Volume-regulated Anion Channels (VRACs) Depend on C-terminal Residues of the First Extracellular Loop
Published in The Journal of biological chemistry (12-08-2016)“…Canonical volume-regulated anion channels (VRACs) are crucial for cell volume regulation and have many other important roles, including tumor drug resistance…”
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Journal Article -
3
CAR links hypoxia signaling to improved survival after myocardial infarction
Published in Experimental & molecular medicine (01-03-2023)“…The coxsackievirus and adenovirus receptor (CAR) mediates homo- and heterotopic interactions between neighboring cardiomyocytes at the intercalated disc. CAR…”
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VRAC: molecular identification as LRRC8 heteromers with differential functions
Published in Pflügers Archiv (01-03-2016)“…A major player of vertebrate cell volume regulation is the volume-regulated anion channel (VRAC), which conducts halide ions and organic osmolytes to…”
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Journal Article Book Review -
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Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs
Published in The EMBO journal (14-12-2015)“…Although platinum‐based drugs are widely used chemotherapeutics for cancer treatment, the determinants of tumor cell responsiveness remain poorly understood…”
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Subunit composition of VRAC channels determines substrate specificity and cellular resistance to P t‐based anti‐cancer drugs
Published in The EMBO journal (14-12-2015)Get full text
Journal Article