Search Results - "Voso, M T"
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Expression profiling of extramedullary acute myeloid leukemia suggests involvement of epithelial–mesenchymal transition pathways
Published in Leukemia (01-12-2023)“…Extramedullary (EM) colonization is a rare complication of acute myeloid leukemia (AML), occurring in about 10% of patients, but the processes underlying…”
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Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine
Published in Leukemia (01-03-2014)“…The nucleoside analog azacitidine (AZA) is used in the treatment of myelodysplastic syndromes (MDS), but 30–40% of patients fail to respond or relapse after…”
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Early and sensitive detection of PML-A216V mutation by droplet digital PCR in ATO-resistant acute promyelocytic leukemia
Published in Leukemia (01-06-2019)Get full text
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Cell-free circulating DNA in Hodgkin's and non-Hodgkin's lymphomas
Published in Annals of oncology (01-08-2009)“…Levels of cell-free circulating DNA have been correlated to clinical characteristics and prognosis in patients with cancers of epithelial origin, while there…”
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Preference for involvement in treatment decisions and request for prognostic information in newly diagnosed patients with higher-risk myelodysplastic syndromes
Published in Annals of oncology (01-02-2014)“…The main objective of this study was to assess preferences for involvement in treatment decisions and requests for prognostic information in newly diagnosed…”
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The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia
Published in Frontiers in cell and developmental biology (22-07-2022)“…Data derived from high-throughput sequencing technologies have allowed a deeper understanding of the molecular landscape of Acute Myeloid Leukemia (AML),…”
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Bone Marrow Microenvironment Involvement in t-MN: Focus on Mesenchymal Stem Cells
Published in Mediterranean journal of hematology and infectious diseases (01-09-2023)“…Therapy-related myeloid neoplasms (t-MN) are a late complication of cytotoxic therapy (CT) used in the treatment of both malignant and non-malignant diseases…”
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Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-Azacytidine
Published in Leukemia (01-12-2011)Get full text
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Prevalence of HCV infection in nongastric marginal zone B-cell lymphoma of MALT
Published in Annals of oncology (01-02-2007)“…Background: Hepatitis C virus (HCV) infection is frequently associated with B-cell non-Hodgkin's lymphomas. We investigated the prevalence of HCV infection in…”
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Risk of acute promyelocytic leukemia in multiple sclerosis: Coding variants of DNA repair genes
Published in Neurology (22-03-2011)“…Single nucleotide polymorphisms (SNPs) in double-strand break repair genes may alter DNA repair capacity and, in turn, confer predisposition to leukemia. We…”
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Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma
Published in Annals of oncology (01-08-2007)“…Background: In Hodgkin's lymphoma (HL), the production of cytokines by Reed–Sternberg cells and the surrounding tissue is thought to contribute to the biology…”
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Increased risk of acute myeloid leukaemia due to polymorphisms in detoxification and DNA repair enzymes
Published in Annals of oncology (01-09-2007)“…Background: Polymorphisms in genes involved in detoxification and DNA-repair pathways may modify the individual's risk for genomic damage, and, as a…”
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Prognostic role of glutathione S-transferase polymorphisms in acute myeloid leukemia
Published in Leukemia (01-09-2008)“…Glutathione S -transferases (GSTs) are phase II detoxification enzymes involved in the metabolism of carcinogens and anticancer drugs, known also to interact…”
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Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach to classification of patients with t-MDS
Published in Leukemia (01-03-2021)“…In the current World Health Organization (WHO)-classification, therapy-related myelodysplastic syndromes (t-MDS) are categorized together with therapy-related…”
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Acute Promyelocytic Leukemia: Update on the Mechanisms of Leukemogenesis, Resistance and on Innovative Treatment Strategies
Published in Cancers (18-10-2019)“…This review highlights new findings that have deepened our understanding of the mechanisms of leukemogenesis, therapy and resistance in acute promyelocytic…”
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The anti-leukemic effect of a novel histone deacetylase inhibitor MCT-1 and 5-aza-cytidine involves augmentation of Nur77 and inhibition of MMP-9 expression
Published in International journal of oncology (01-02-2009)“…A combination of demethylating agents and histone deacetylase inhibitors (HDACi) has been proposed as a novel therapy in leukemia and myelodysplasia. In HL-60…”
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PML–RARα kinetics and impact of FLT3–ITD mutations in newly diagnosed acute promyelocytic leukaemia treated with ATRA and ATO or ATRA and chemotherapy
Published in Leukemia (01-10-2016)“…The APL0406 study showed that arsenic trioxide (ATO) and all -trans retinoic acid (ATRA) are not inferior to standard ATRA and chemotherapy (CHT) in newly…”
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Therapy-related leukemia and myelodysplasia: susceptibility and incidence
Published in Haematologica (Roma) (01-10-2007)“…From Istituto di Ematologia, Università Cattolica S. Cuore, Rome, Italy (GP, LP, MTV); Department of Hematology, Hadassah University Hospital, Jerusalem,…”
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