Search Results - "Vosen, Sarah"
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Endothelial Microparticle–Mediated Transfer of MicroRNA-126 Promotes Vascular Endothelial Cell Repair via SPRED1 and Is Abrogated in Glucose-Damaged Endothelial Microparticles
Published in Circulation (New York, N.Y.) (29-10-2013)“…BACKGROUND—Repair of the endothelium after vascular injury is crucial for preserving endothelial integrity and preventing the development of vascular disease…”
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Identification of Magnetic Nanoparticles for Combined Positioning and Lentiviral Transduction of Endothelial Cells
Published in Pharmaceutical research (01-05-2012)“…Purpose The combination of magnetic nanoparticles (MNPs) with a magnetic field is a powerful approach to enable cell positioning and/or local gene therapy…”
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Vascular Repair by Circumferential Cell Therapy Using Magnetic Nanoparticles and Tailored Magnets
Published in ACS nano (26-01-2016)“…Cardiovascular disease is often caused by endothelial cell (EC) dysfunction and atherosclerotic plaque formation at predilection sites. Also surgical…”
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Improvement of vascular function by magnetic nanoparticle-assisted circumferential gene transfer into the native endothelium
Published in Journal of controlled release (10-11-2016)“…Gene therapy is a promising approach for chronic disorders that require continuous treatment such as cardiovascular disease. Overexpression of vasoprotective…”
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Analysis of Trajectories for Targeting of Magnetic Nanoparticles in Blood Vessels
Published in Molecular pharmaceutics (02-07-2012)“…The technique of magnetic drug targeting deals with binding drugs or genetic material to superparamagnetic nanoparticles and accumulating these complexes via…”
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Optimization of Magnetic Nanoparticle-Assisted Lentiviral Gene Transfer
Published in Pharmaceutical research (01-05-2012)“…Purpose Targeting of specific cells and tissues is of great interest for clinical relevant gene- and cell-based therapies. We use magnetic nanoparticles (MNPs)…”
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Optogenetic Control of Vascular Tone with High Temporal Resolution
Published in Biophysical journal (29-01-2013)Get full text
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Radially symmetric endothelial cell replacement and lentiviral targeting in vessels by the use of magnetic nanoparticles (MNPs)
Published in The FASEB journal (01-04-2011)“…Endothelial cell damage often occurs in vascular disease such as atherosclerosis resulting in loss of vasoregulation and/or thrombosis. To restore endothelial…”
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