Search Results - "Vos, Ricardo"
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Altered secretory and neuroprotective function of the choroid plexus in progressive multiple sclerosis
Published in Acta neuropathologica communications (19-03-2020)“…The choroid plexus (CP) is a key regulator of the central nervous system (CNS) homeostasis through its secretory, immunological and barrier properties…”
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PET imaging of P2X7R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [11C]SMW139
Published in Journal of neuroinflammation (14-10-2020)“…Abstract Background Non-invasive imaging of the activation status of microglia and the ability to identify a pro- or anti-inflammatory environment can provide…”
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3
In-vivo monitoring of anti-folate therapy in arthritic rats using [ 18 F]fluoro-PEG-folate and positron emission tomography
Published in Arthritis research & therapy (31-05-2017)“…Folate receptor β (FRβ) is involved in facilitating cellular uptake of folates and anti-folates (such as methotrexate (MTX)). In rheumatoid arthritis, FRβ is…”
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4
Performance of nanoScan PET/CT and PET/MR for quantitative imaging of 18F and 89Zr as compared with ex vivo biodistribution in tumor-bearing mice
Published in EJNMMI research (12-06-2021)“…Introduction The assessment of ex vivo biodistribution is the preferred method for quantification of radiotracers biodistribution in preclinical models, but is…”
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Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [ 89 Zr]Zr-DFO-PEG 5 -Tz
Published in Bioconjugate chemistry (18-05-2022)“…The recent advances in the production of engineered antibodies have facilitated the development and application of tailored, target-specific antibodies…”
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Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [89Zr]Zr-DFO-PEG5‑Tz
Published in Bioconjugate chemistry (18-05-2022)“…The recent advances in the production of engineered antibodies have facilitated the development and application of tailored, target-specific antibodies…”
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Synthesis and Preclinical Evaluation of the First Carbon-11 Labeled PET Tracers Targeting Substance P 1-7
Published in Molecular pharmaceutics (05-11-2018)“…Two potent SP peptidomimetics have been successfully radiolabeled via [ C]CO -fixation with excellent yields, purity, and molar activity. l-[ C]SP…”
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Prophylactic and therapeutic activity of alkaline phosphatase in arthritic rats: single-agent effects of alkaline phosphatase and synergistic effects in combination with methotrexate
Published in Translational research : the journal of laboratory and clinical medicine (01-09-2018)“…Alkaline phosphatase (AP) is a gate-keeper of innate immune system responses by detoxifying inflammation triggering moieties released from endogenous and…”
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Synthesis and Preclinical Evaluation of the First Carbon-11 Labeled PET Tracers Targeting Substance P1–7
Published in Molecular pharmaceutics (05-11-2018)“…Two potent SP1–7 peptidomimetics have been successfully radiolabeled via [11C]CO2-fixation with excellent yields, purity, and molar activity…”
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