Search Results - "Vos, Larissa J."

Multidisciplinary Approach to Novel Therapies in Cardio-Oncology Research (MANTICORE 101-Breast): A Randomized Trial for the Prevention of Trastuzumab-Associated Cardiotoxicity by Pituskin, Edith, Mackey, John R, Koshman, Sheri, Jassal, Davinder, Pitz, Marshall, Haykowsky, Mark J, Pagano, Joseph J, Chow, Kelvin, Thompson, Richard B, Vos, Larissa J, Ghosh, Sunita, Oudit, Gavin Y, Ezekowitz, Justin A, Paterson, D Ian

“…Purpose The primary toxicity of trastuzumab therapy for human epidermal growth factor receptor 2-overexpressing (HER2-positive) breast cancer is…”
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A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors by Chu, Quincy Siu-Chung, Sangha, Randeep, Spratlin, Jennifer, J. Vos, Larissa, Mackey, John R., McEwan, Alexander J. B., Venner, Peter, Michelakis, Evangelos D.

“…Summary Purpose Preclinical evidence suggests dichloroacetate (DCA) can reverse the Warburg effect and inhibit growth in cancer models. This phase 1 study was…”
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Chemotherapy-induced weight gain in early-stage breast cancer: a prospective matched cohort study reveals associations with inflammation and gut dysbiosis by Walker, John, Joy, Anil Abraham, Vos, Larissa J, Stenson, Trevor H, Mackey, John R, Jovel, Juan, Kao, Dina, Madsen, Karen L, Wong, Gane Ka-Shu

“…Early-stage breast cancer patients treated with chemotherapy risk the development of metabolic disease and weight gain, which can result in increased morbidity…”
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Dynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acid by Famulski, Jakub K, Vos, Larissa J, Rattner, Jerome B, Chan, Gordon K

“…The mitotic checkpoint functions to ensure accurate chromosome segregation by regulating the progression from metaphase to anaphase. Once the checkpoint has…”
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PDGFRα Regulates Follicular Cell Differentiation Driving Treatment Resistance and Disease Recurrence in Papillary Thyroid Cancer by Lopez-Campistrous, Ana, Adewuyi, Esther Ekpe, Benesch, Matthew G.K., Ko, Yi Man, Lai, Raymond, Thiesen, Aducio, Dewald, Jay, Wang, Peng, Chu, Karen, Ghosh, Sunita, Williams, David C., Vos, Larissa J., Brindley, David N., McMullen, Todd P.W.

“…Dedifferentiation of follicular cells is a central event in resistance to radioactive iodine and patient mortality in papillary thyroid carcinoma (PTC). We…”
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hZwint-1 bridges the inner and outer kinetochore: identification of the kinetochore localization domain and the hZw10-interaction domain by Vos, Larissa J, Famulski, Jakub K, Chan, Gordon K T

“…Accurate chromosome segregation in mitosis is required to maintain genetic stability. hZwint-1 [human Zw10 (Zeste white 10)-interacting protein 1] is a…”
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Role of serial multiparametric magnetic resonance imaging in prostate cancer active surveillance by Vos, Larissa J, Janoski, Michele, Wachowicz, Keith, Yahya, Atiyah, Boychak, Oleksandr, Amanie, John, Pervez, Nadeem, Parliament, Matthew B, Pituskin, Edith, Fallone, B Gino, Usmani, Nawaid

“…AIM:To examine whether addition of 3T multiparametric magnetic resonance imaging(mp MRI)to an active surveillance protocol could detect aggressive or…”
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Combination of submandibular salivary gland transfer and intensity‐modulated radiotherapy to reduce dryness of mouth (xerostomia) in patients with head and neck cancer by Scrimger, Rufus A, Seikaly, Hadi, Vos, Larissa J., Harris, Jeffrey, O'Connell, Dan, Ghosh, Sunita, Debenham, Brock, Jha, Naresh

“…Background Xerostomia is a debilitating side effect of radiotherapy for head and neck cancer. Combining surgical submandibular‐gland transfer (SMGT) with…”
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Patient reported quality of life after helical IMRT based concurrent chemoradiation of locally advanced anal cancer by Joseph, Kurian, Vos, Larissa J, Warkentin, Heather, Paulson, Kim, Polkosnik, Lee-anne, Usmani, Nawaid, Tankel, Keith, Severin, Diane, Nijjar, Tirath, Schiller, Dan, Wong, Clarence, Ghosh, Sunita, Mulder, Karen, Field, Colin

“…Abstract Background and purpose Concurrent chemoradiation (CCRT) is the standard treatment for locally advanced anal canal carcinoma, although…”
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Uridine Glucuronosyltransferase 2B7 Polymorphism-Based Pharmacogenetic Dosing of Epirubicin in FEC Chemotherapy for Early-Stage Breast Cancer by Joy, Anil A., Vos, Larissa J., Pituskin, Edith, Cook, Sarah F., Bies, Robert R., Vlahadamis, Ann, King, Karen, Basi, Sanraj K., Meza-Junco, Judith, Mackey, John R., Stanislaus, Avalyn, Damaraju, Vijaya L., Damaraju, Sambasivarao, Sawyer, Michael B.

“…Epirubicin is metabolized by uridine glucuronosyltransferase 2B7 (UGT2B7). Patients homozygous for the minor allele (CC) in the UGT2B7 -161 promoter…”
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Clinical Outcomes of the CHIRP Trial: A Phase II Prospective Randomized Trial of Conventionally Fractionated Versus Moderately Hypofractionated Prostate and Pelvic Nodal Radiation Therapy in Patients With High-Risk Prostate Cancer by Wang, Michael H., Vos, Larissa J., Yee, Don, Patel, Samir, Pervez, Nadeem, Parliament, Matthew, Usmani, Nawaid, Danielson, Brita, Amanie, John, Pearcey, Robert, Ghosh, Sunita, Field, Colin, Fallone, B. Gino, Murtha, Albert D.

“…Hypofractionated radiation therapy (HFRT) may offer treatment advantages for patients with prostate cancer. However, HFRT may also increase the risk of…”
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A population-based study examining the influence of a specialized rapid-access cancer clinic on initial treatment choice in localized prostate cancer by Vos, Larissa J, Ho, Clement K, Donnelly, Bryan J, Reuther, J Dean, Kerba, Marc

“…Treatment decisions in localized prostate cancer are complicated by the available choices. A rapid-access cancer clinic (RAC) has been unique to Calgary, AB,…”
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A Uridine Glucuronosyltransferase 2B7 Polymorphism Predicts Epirubicin Clearance and Outcomes in Early-Stage Breast Cancer by Sawyer, Michael B, Pituskin, Edith, Damaraju, Sambasivarao, Bies, Robert R, Vos, Larissa J, Prado, Carla. M.M, Kuzma, Michelle, Scarfe, Andrew G, Clemons, Mark, Tonkin, Katia, Au, Heather-Jane, Koski, Sheryl, Joy, Anil A, Smylie, Michael, King, Karen, Carandang, Diana, Damaraju, Vijaya L, Hanson, John, Cass, Carol E, Mackey, John R

“…Micro-Abstract An epirubicin dose of 100 mg/m2 is well tolerated by most patients; however, a subset will experience dose-limiting toxicity. We observed…”
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How to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly by Vos, Larissa J, Famulski, Jakub K, Chan, Gordon K T

“…The assembly of the centromere, a specialized region of DNA along with a constitutive protein complex which resides at the primary constriction and is the site…”
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172: Five-Year Survival, Toxicity, and Patient Reported Quality of Life After Intensity Modulated Radiation Therapy-Based Concorrent Chemoradiotherapy for Locally Advanced Anal Cancer by Al Balushi, Mustafa, Vos, Larissa J., Menon, Anjali, Abraham, Aswin, Warkentin, Heather, Ghosh, Sunita, Paulson, Kim, Usmani, Nawaid, Tankel, Keith, Severin, Diane, Nijjar, Tirath, Schiller, Dan, Wong, Clarence, Mulder, Karen, Doll, Corinne, Joseph, Kurian

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Correction: Dynein/Dynactin-Mediated Transport of Kinetochore Components off Kinetochores and onto Spindle Poles Induced by Nordihydroguaiaretic Acid by Famulski, Jakub K., Vos, Larissa J., Rattner, Jerome B., Chan, Gordon K.

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Correction: Dynein/Dynactin-Mediated Transport of Kinetochore Components off Kinetochores and onto Spindle Poles Induced by Nordihydroguaiaretic Acid by Jakub K. Famulski, Larissa J. Vos, Jerome B. Rattner, Gordon K. Chan

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