Search Results - "Vos, A.M. de"
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Nerve growth factor: structure and function
Published in Cellular and molecular life sciences : CMLS (01-05-2001)“…Neurotrophins are critical for the development and maintenance of the peripheral and central nervous system. These highly homologous, homodimeric growth…”
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Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen
Published in Journal of molecular biology (05-11-1999)“…The Fab portion of a humanized antibody (Fab-12; IgG form known as rhuMAb VEGF) to vascular endothelial growth factor (VEGF) has been affinity-matured through…”
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Triggering Cell Death: The Crystal Structure of Apo2L/TRAIL in a Complex with Death Receptor 5
Published in Molecular cell (01-10-1999)“…Formation of a complex between Apo2L (also called TRAIL) and its signaling receptors, DR4 and DR5, triggers apoptosis by inducing the oligomerization of…”
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Three-dimensional structure of thaumatin I, an intensely sweet protein
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1985)“…Thaumatin and monellin are the two sweetest compounds known to man--about 100,000 times sweeter than sugar on a molar basis and 3000 times on a weight basis…”
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Progress in noninvasive coronary artery imaging using multislice CT
Published in Netherlands heart journal (01-09-2005)“…Conventional coronary angiography (CAG) has been the reference standard for the assessment of coronary artery disease since its introduction in 1958. However,…”
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Adolescent with occluded left main coronary artery
Published in Netherlands heart journal (01-06-2005)“…Here we report unexpected findings in a 17-year-old female patient referred for coronary angiography and percutaneous intervention. During the angiography we…”
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Mutations of ovine and bovine placental lactogens change, in different ways, the biological activity mediated through homologous and heterologous lactogenic receptors
Published in Journal of endocrinology (01-04-2001)“…The biological activities of ovine (o) and bovine (b) placental lactogens (PLs) and their mutated analogues were compared using several binding and in vitro…”
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