Search Results - "Vorup‐Jensen, T."

Targets and Mechanisms in Prevention of Parkinson's Disease through Immunomodulatory Treatments by Euler Chelpin, M., Vorup‐Jensen, T.

“…Parkinson's disease (PD) is the second most common neurodegenerative disease in the world; however, there is no cure for it. Current treatments only relieve…”
Get full text

Altered levels of soluble CD18 may associate immune mechanisms with outcome in sepsis by Kragstrup, T. W., Juul‐Madsen, K., Christiansen, S. H., Zhang, X., Krog, J., Vorup‐Jensen, T., Kjærgaard, A. G.

“…Summary The pathogenesis of sepsis involves a dual inflammatory response, with a hyperinflammatory phase followed by, or in combination with, a…”
Get full text

The effect of IgG levels on the number of natural killer cells and their Fc receptors in chronic inflammatory demyelinating polyradiculoneuropathy by Bohn, A. B., Nederby, L., Harbo, T., Skovbo, A., Vorup-Jensen, T., Krog, J., Jakobsen, J., Hokland, M. E.

“…Background and purpose:  High‐dose intravenous immunoglobulin (IVIg) is an established treatment for chronic inflammatory demyelinating polyradiculoneuropathy…”
Get full text

Synthesis of Functional Nanomaterials via Colloidal Mask Templating and Glancing Angle Deposition (GLAD) by Dolatshahi-Pirouz, A., Jensen, T., Vorup-Jensen, T., Bech, Rikke, Chevallier, J., Besenbacher, F., Foss, M., Sutherland, D.S.

“…We present a simple method for the fabrication of separated brush‐like networks with both improved optical and biological properties. The brush networks were…”
Get full text

P1134 : The leukocyte migration inhibitor soluble CD18 increases with severity of human alcoholic hepatitis by Stoey, S, Sandahl, T.D, Deleuran, B, Vorup-Jensen, T, Vilstrup, H, Kragstrup, T.W

Get full text

Development of an Airway Epithelium In Vitro Model System by Papazian, D, Arge, M, Chhoden, T, Vorup-Jensen, T, Nielsen, C, Skjoedt, K, Lund, K, Wurtzen, P.A, Hansen, S

Get full text

Interaction Properties of Human Mannan-Binding Lectin (MBL)-Associated Serine Proteases-1 and -2, MBL-Associated Protein 19, and MBL by Thielens, Nicole M, Cseh, Sandor, Thiel, Steffen, Vorup-Jensen, Thomas, Rossi, Veronique, Jensenius, Jens C, Arlaud, Gerard J

“…The mannan-binding lectin (MBL) activation pathway of complement plays an important role in the innate immune defense against pathogenic microorganisms. In…”
Get full text

The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3 by Stover, C, Endo, Y, Takahashi, M, Lynch, N J, Constantinescu, C, Vorup-Jensen, T, Thiel, S, Friedl, H, Hankeln, T, Hall, R, Gregory, S, Fujita, T, Schwaeble, W

“…The proteases of the lectin pathway of complement activation, MASP-1 and MASP-2, are encoded by two separate genes. The MASP1 gene is located on chromosome…”
Get full text

520: The antimicrobial peptide glatiramer acetate disrupts pseudomonal cell membranes through interaction with lipopolysaccharide by Murphy, R., Sabnis, A., Harrison, J., Schelenz, S., Edwards, A., Vorup-Jensen, T., Davies, J.

Get full text

X-ray microscopy of human spermatozoa shows change of mitochondrial morphology after capacitation by Vorup-Jensen, Thomas, Hjort, Tage, Abraham-Peskir, Joanna V., Guttmann, Peter, Jensenius, Jens C., Uggerhøj, Erik, Medenwaldt, Robin

“…Using X-ray microscopy two morphologically distinct states were observed of the human spermatozoan mitochondria: (i) compact and tightly wrapped around the…”
Get full text

EPS3.04 Depolarisation of the Pseudomonas aeruginosa cytoplasmic membrane by Glatiramer acetate potentiates the antibacterial activity of tobramycin by Murphy, R.A., Thrane, S., Harrison, J., Schelenz, S., Vorup-Jensen, T., Davies, J.C.

Get full text

Nanotoxicity: From Bench to Bedside by PEER, D, VORUP-JENSEN, T

Get full text

ePS6.10 Glatiramer acetate improves the killing ability of tobramycin in Pseudomonas aeruginosa cultured from cystic fibrosis clinical samples by Murphy, R.A., Thrane, S., Harrisson, J., Schelenz, S., Vorup-Jensen, T., Davies, J.C.

Get full text

Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease by Parbo, Peter, Madsen, Lasse Stensvig, Ismail, Rola, Zetterberg, Henrik, Blennow, Kaj, Eskildsen, Simon F, Vorup-Jensen, Thomas, Brooks, David J

“…Plasma and cerebrospinal fluid levels of neurofilament light (NfL), a marker of axonal degeneration, have previously been reported to be raised in patients…”
Get full text

Structural insight on the recognition of complement activator bound opsonins by complement receptor 3 by Bajic, G., Yatime, L., Vorup-Jensen, T., Andersen, G.R.

Get full text

Identification of the target self-antigens in reperfusion injury by Zhang, Ming, Alicot, Elisabeth M, Chiu, Isaac, Li, Jinan, Verna, Nicola, Vorup-Jensen, Thomas, Kessler, Benedikt, Shimaoka, Motomu, Chan, Rodney, Friend, Daniel, Mahmood, Umar, Weissleder, Ralph, Moore, Francis D, Carroll, Michael C

“…Reperfusion injury (RI), a potential life-threatening disorder, represents an acute inflammatory response after periods of ischemia resulting from myocardial…”
Get full text

Studies of recombinant MBL and MASP-2: Is MASP-2 self-activating? by Vorup-Jensen, Thomas, Davis, S.J., Poulsen, K., Schwaeble, W., Stover, C.M., Sim, R., Reid, K.B.M., Petersen, S.V., Thiel, S., Jensenius, J.C.

Get full text

MASP-3 and Its Association with Distinct Complexes of the Mannan-Binding Lectin Complement Activation Pathway by Dahl, Mads R., Thiel, Steffen, Matsushita, Misao, Fujita, Teizo, Willis, Anthony C., Christensen, Tove, Vorup-Jensen, Thomas, Jensenius, Jens C.

“…The mannan-binding lectin (MBL) pathway of complement activation is part of the innate immune defense. The binding of MBL to microbial carbohydrates activates…”
Get full text

Structure and allosteric regulation of the alpha X beta 2 integrin I domain by Vorup-Jensen, Thomas, Ostermeier, Christian, Shimaoka, Motomu, Hommel, Ulrich, Springer, Timothy A

“…The integrin alpha X beta 2 (CD11c/CD18, p150,95) binds ligands through the I domain of the alpha X subunit. Ligands include the complement factor fragment…”
Get full text

A second serine protease associated with mannan-binding lectin that activates complement by Thiel, Steffen, Vorup-Jensen, Thomas, Stover, Cordula M, Schwaeble, Wilhelm, Laursen, Steen B, Poulsen, Knud, Willis, Anthony C, Eggleton, Paul, Hansen, Søren, Holmskov, Uffe, Reid, Kenneth B. M, Jensenius, Jens C

“…The complement system comprises a complex array of enzymes and non-enzymatic proteins that is essential for the operation of the innate as well as the adaptive…”
Get full text