Search Results - "Voruganti, Saroja"
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Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
Published in PloS one (14-12-2012)“…Genetic variants responsible for susceptibility to obesity and its comorbidities among Hispanic children have not been identified. The VIVA LA FAMILIA Study…”
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Global metabolomic profiling targeting childhood obesity in the Hispanic population
Published in The American journal of clinical nutrition (01-08-2015)“…Metabolomics may unravel important biological pathways involved in the pathophysiology of childhood obesity. We aimed to 1) identify metabolites that differ…”
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Eighty years of nutritional sciences, and counting
Published in Nutrition reviews (08-12-2021)Get full text
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Heterogeneity in Metabolic Responses to Dietary Fructose
Published in Frontiers in genetics (31-10-2019)“…Consumption of fructose has dramatically increased in past few decades in children and adults. Increasing evidence indicates that added sugars (particularly…”
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Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study
Published in PloS one (17-10-2019)“…Increased serum levels of C-reactive protein (CRP), an important component of the innate immune response, are associated with increased risk of cardiovascular…”
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Arsenic, blood pressure, and hypertension in the Strong Heart Family Study
Published in Environmental research (01-04-2021)“…Arsenic has been associated with hypertension, though it is unclear whether associations persist at the exposure concentrations (e.g. <100 μg/L) in drinking…”
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Genome Scan for Determinants of Serum Uric Acid Variability
Published in Journal of the American Society of Nephrology (01-12-2007)“…Elevated serum uric acid level is associated with obesity, insulin resistance, diabetes, nephropathy, and hypertension. Epidemiologic studies suggest that…”
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Association of Cardiometabolic Genes with Arsenic Metabolism Biomarkers in American Indian Communities: The Strong Heart Family Study (SHFS)
Published in Environmental health perspectives (01-01-2017)“…Metabolism of inorganic arsenic (iAs) is subject to inter-individual variability, which is explained partly by genetic determinants. We investigated the…”
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Genetic variants affecting bone mineral density and bone mineral content at multiple skeletal sites in Hispanic children
Published in Bone (New York, N.Y.) (01-03-2020)“…Osteoporosis is a major public health burden with significant economic costs. However, the correlates of bone health in Hispanic children are understudied. We…”
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Precision Nutrition: Recent Advances in Obesity
Published in Physiology (Bethesda, Md.) (01-01-2023)“…"Precision nutrition" is an emerging area of nutrition research that focuses on understanding metabolic variability within and between individuals and helps…”
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Both Rare and Common Variants in PCSK9 Influence Plasma Low-Density Lipoprotein Cholesterol Level in American Indians
Published in The journal of clinical endocrinology and metabolism (01-02-2015)“…Context: Elevated LDL cholesterol (LDL-C) is an important risk factor for atherosclerosis and cardiovascular disease. Variants in the proprotein convertase…”
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Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association
Published in American journal of respiratory and critical care medicine (01-03-2019)“…Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have anti-inflammatory properties that could benefit adults with comprised pulmonary health. To investigate n-3…”
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Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus
Published in Cell reports (Cambridge) (10-11-2015)“…Brain-derived neurotrophic factor (BDNF) plays a key role in energy balance. In population studies, SNPs of the BDNF locus have been linked to obesity, but the…”
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Physiological and Molecular Determinants of Insulin Action in the Baboon
Published in Diabetes (New York, N.Y.) (01-04-2008)“…Physiological and Molecular Determinants of Insulin Action in the Baboon Alberto O. Chavez 1 , Juan C. Lopez-Alvarenga 2 3 , M. Elizabeth Tejero 2 , Curtis…”
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The association of genetic variants of type 2 diabetes with kidney function
Published in Kidney international (01-07-2012)“…Type 2 diabetes is highly prevalent and is the major cause of progressive chronic kidney disease in American Indians. Genome-wide association studies…”
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Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children
Published in The American journal of clinical nutrition (2010)“…BACKGROUND: Melanocortin-4-receptor (MC4R) haploinsufficiency is the most common form of monogenic obesity; however, the frequency of MC4R variants and their…”
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Heritability and preliminary genome-wide linkage analysis of arsenic metabolites in urine
Published in Environmental health perspectives (01-03-2013)“…Arsenic (III) methyltransferase (AS3MT) has been related to urine arsenic metabolites in association studies. Other genes might also play roles in arsenic…”
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Heritability of Measures of Kidney Disease Among Zuni Indians: The Zuni Kidney Project
Published in American journal of kidney diseases (01-08-2010)“…Background The long-term goal of the GKDZI (Genetics of Kidney Disease in Zuni Indians) Study is to identify genes, environmental factors, and…”
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Consistent Directions of Effect for Established Type 2 Diabetes Risk Variants Across Populations: The Population Architecture using Genomics and Epidemiology (PAGE) Consortium
Published in Diabetes (New York, N.Y.) (01-06-2012)“…Common genetic risk variants for type 2 diabetes (T2D) have primarily been identified in populations of European and Asian ancestry. We tested whether the…”
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Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study
Published in BMC medical genetics (17-01-2017)“…Reduced renal excretion of uric acid plays a significant role in the development of hyperuricemia and gout in adults. Hyperuricemia has been associated with…”
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