Search Results - "Vorontsov, E. A"

Composition and Antimicrobial Activity of the Skin Peptidome of Russian Brown Frog Rana temporaria by Samgina, T. Yu, Vorontsov, E. A, Gorshkov, V. A, Hakalehto, E, Hanninen, O, Zubarev, R. A, Lebedev, A. T

“…A nano-HPLC-ESI-OrbiTrap study involving HCD and ETD spectra has been carried out to clarify the composition of the skin peptidome of brown Russian frogs Rana…”
Get full text

A new system for targeted delivery of doxorubicin into tumor cells by Yabbarov, N.G., Posypanova, G.A., Vorontsov, E.A., Obydenny, S.I., Severin, E.S.

“…The use of vector molecules for the targeted delivery of antitumor drugs provides their selectivity for cancer cells. The recombinant receptor-binding fragment…”
Get full text

Targeted delivery of doxorubicin: Drug delivery system based on PAMAM dendrimers by Yabbarov, N. G., Posypanova, G. A., Vorontsov, E. A., Popova, O. N., Severin, E. S.

“…Polyamidoamine (PAMAM) dendrimers of the second generation (G2) are branched polymers containing 16 surface amino groups that allow them to be used as…”
Get full text

Molecular mechanisms of antitumor activity of the polymeric form of niclosamide with respect to human colorectal cancer cells by Zhirnik, A. S., Semochkina, Yu. P., Moskaleva, E. Yu, Krylov, N. I., Tubasheva, I. A., Kuznetsov, S. L., Vorontsov, E. A.

“…Using poly(lactic-co-glycolic) acid a polymeric form of niclosamide (PFN) has been developed and its antitumor activity against human colorectal cancer cell…”
Get full text

Antitumor Activity of a Polymer Composite of Etoposide and Biodegradable Poly(Lactide-Co-Glycolide) by Posypanova, G. A., Gorshkova, L. B., Rodina, A. V., Semochkina, Yu. P., Perevozchikova, V. G., Moskaleva, E. Yu, Ratushnyak, M. G., Vorontsov, E. A., Kuznetsov, S. L., Tubasheva, I. A., Murav’eva, A. I., Severin, S. E.

“…A method for preparing an antitumor polymer form of etoposide (PFE) as submicron particles based on poly(lactide-co-glycolide) with a 50:50 ratio of monomers…”
Get full text

Targeted delivery of paclitaxel-loaded recombinant α-fetoprotein fragment-conjugated nanoparticles to tumor cells by Godovannyi, A. V., Vorontsov, E. A., Gukasova, N. V., Pozdnyakova, N. V., Vasilenko, E. A., Yabbarov, N. G., Dubovik, E. G., Severin, S. E., Severin, E. S., Gnuchev, N. V.

Get full text

Antibacterial Activity of the Polymeric Form of Josamycin by E. D. Nikolskaya, O. A. Zhunina, M. B. Sokol, M. V. Fomicheva, N. V. Gukasova, E. A. Vorontsov, N. G. Yabbarov, O. G. Tereshchenko, E. S. Severin

“…The polymeric form ofjosamycin was developed by loading of the antibiotic into spherical submicron particles made of poly(DL- lactide-co-glycolide) (PLGA…”
Get full text

Pharmacokinetics and Biodistribution of Anastrozole in a Polymer-Containing Formulation by Gukasova, N. V., Tubasheva, I. A., Kuznetsov, S. L., Aleshin, S. V., Sokolov, V. V., Antipova, T. A., Poltavets, Yu. I., Krasheninnikova, A. A., Vorontsov, E. A.

“…A polymer-containing anastrozole formulation (PAF) in the form of micronized particles based on a copolymer of lactic and glycolic acids with a terminal…”
Get full text

Comparative Pharmacokinetics and Biodistribution of Etoposide in a Polymer Dosage Form and as Free Drug Substance by Gukasova, N. V., Tubasheva, I. A., Kuznetsov, S. L., Murav’eva, A. I., Aleshin, S. V., Sokolov, V. V., Antipova, T. A., Vorontsov, E. A.

“…A polymer dosage form of etoposide (PFE) was obtained as submicron particles based on the copolymer of lactic and glycolic acids (PLGA). Pharmacokinetics and…”
Get full text

Synthesis and study of the effect of uracil and theophylline derivatives on the glucose transport into rat hepatic cells by Leonov, O. N., Tsyrenina, M. L., Melnik, E. I., Devichenskii, V. M., Kryukova, L. Yu, Vorontsov, E. A., Kuznetsov, S. L., Kryukov, L. N.

“…A series of uracil and theophylline derivatives was synthesized. 4-Amino-1,3-dimethyl-5-non-anoylaminouracil displayed the most pronounced effect of thein…”
Get full text

Antineoplastic mechanisms of niclosamide-loaded nanoparticles in human colorectal cancer cells by Zhirnik, A S, Semochkina, Y P, Moskaleva, E Yu, Krylov, N I, Tubasheva, I A, Kuznetsov, S L, Vorontsov, E A

“…Using poly(lactic-co-glycolic) acid we developed a polymeric form of niclosamide (PFN) and investigated molecular mechanisms underlying its antitumor activity…”
Get more information

Design of etoposide polymeric forms by Murav’eva, A. I., Vorontsov, E. A., Gukasova, N. V., Zavarzina, V. V., Kuznetsov, S. L., Tubasheva, I. A., Semochkina, Yu. P., Moskaleva, E. Yu, Posypanova, G. A., Severin, S. E.

“…The present work relates to the field of pharmacology and medicine, in particular, to a new generation of anticancer drugs based on biocompatible polymers…”
Get full text

Principles of managing ecologically safe architectural reconstruction of the territories affected by waste disposal of different genesis by Potapov, A. D., Vorontsov, E. A., Tupitsyna, O. V., Sukhonosova, A. N., Savel'ev, A. A., Grishin, B. M., Chertes, K. L.

Get full text

Antitumor activity of targeted nanosome delivery systems based on poly(lactic-co-glycolic acid) nanoparticles, paclitaxel, and a recombinant alpha-fetoprotein fragment by Godovannyi, A. V., Vorontsov, E. A., Gukasova, N. V., Pozdnyakova, N. V., Vasilenko, E. A., Yabbarov, N. G., Severin, S. E., Severin, E. S., Gnuchev, N. V.

“…Biodegradable polymeric nanoparticles conjugated with targeting vector molecules have become prospective agents to improve the effectiveness of…”
Get full text

Mass spectrometric de novo sequencing of natural non-tryptic peptides: comparing peculiarities of collision-induced dissociation (CID) and high energy collision dissociation (HCD) by Samgina, Tatyana Yu, Vorontsov, Egor A., Gorshkov, Vladimir A., Artemenko, Konstantin A., Zubarev, Roman A., Lebedev, Albert T.

“…RATIONALE Mass spectrometry has shown itself as the most efficient tool for the sequencing of peptides. However, de novo sequencing of novel natural peptides…”
Get full text

New cysteine-modifying reagents: Efficiency of derivatization and influence on the signals of the protonated molecules of disulfide-containing peptides in matrix-assisted laser desorption/ionization mass spectrometry by Samgina, T. Yu, Gorshkov, V. A., Vorontsov, E. A., Bagrov, V. V., Nifant’ev, I. E., Lebedev, A. T.

“…Mass spectrometric de novo sequencing of skin secretion peptides from genus Rana is complicated because of C-terminal disulfide cycles present in their…”
Get full text

Matrix-Assisted Laser Desorption/Ionization Post-Source Decay Fragmentation of the Cystine-Containing Amphibian Peptides with Novel Cysteine Tags by Vorontsov, E.A., Samgina, T.Yu, Gorshkov, V.A., Poljakov, N.B., Nifant'ev, I.E., Lebedev, A.T.

“…Long disulfide-containing peptides, brevinins 1E and 2Ec, from the skin secretion of the frog Rana ridibunda were reduced and alkylated with ten novel and…”
Get full text

Collision-Induced Dissociation Fragmentation Inside Disulfide C-Terminal Loops of Natural Non-Tryptic Peptides by Samgina, Tatiana Y., Vorontsov, Egor A., Gorshkov, Vladimir A., Artemenko, Konstantin A., Zubarev, Roman A., Ytterberg, Jimmy A., Lebedev, Albert T.

“…Collision-induced dissociation (CID) spectra of long non-tryptic peptides are usually quite complicated and rather difficult to interpret. Disulfide bond…”
Get full text

Targeted delivery of paclitaxel-loaded recombinant [alpha]-fetoprotein fragment-conjugated nanoparticles to tumor cells by Godovannyi, A V, Vorontsov, E A, Gukasova, N V, Pozdnyakova, N V, Vasilenko, E A, Yabbarov, N G, Dubovik, E G, Severin, S E, Severin, E S, Gnuchev, N V

“…Godovannyi et al previously proposed a method for targeted delivery of cytotoxic drugs into tumor cells using alpha fetoprotein (AFP) as a vector molecule…”
Get full text

LC–MS/MS with 2D mass mapping of skin secretions’ peptides as a reliable tool for interspecies identification inside Rana esculenta complex by Samgina, Tatyana Yu, Gorshkov, Vladimir A., Artemenko, Konstantin A., Vorontsov, Egor A., Klykov, Oleg V., Ogourtsov, Sergey V., Zubarev, Roman A., Lebedev, Albert T.

“…► R. esculenta skin peptidome differs from R. ridibunda and R. lessonae peptidomes. ► LC–MS/MS allows easy determination of frog skin peptides. ► 2D maps…”
Get full text