Search Results - "Voronina, TA"
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1
Synthesis and antiamnesic activity of a series of N-acylprolyl-containing dipeptides
Published in European journal of medicinal chemistry (1996)“…Esters and amides of a series of N-acylprolyl-containing dipeptides were synthesized. It was established that these substances possess the ability to prevent…”
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2
Design of New Cognition Enhancers: From Computer Prediction to Synthesis and Biological Evaluation
Published in Journal of medicinal chemistry (20-05-2004)“…To discover new cognition enhancers, a set of virtually designed synthesizable compounds from different chemical series was investigated using two…”
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3
Neuroprotective effects of afobazol in experimental cerebral hemorrhage
Published in Bulletin of experimental biology and medicine (01-11-2005)“…The study of novel selective anxiolytic afobazol on rats with experimental intracerebral post-traumatic hematoma (cerebral hemorrhage) demonstrated its…”
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4
Identification of a novel endogenous memory facilitating cyclic dipeptide cyclo-prolylglycine in rat brain
Published in FEBS letters (05-08-1996)“…Using high-performance liquid chromatography, gas-chromatography and chromato-mass spectrometry methods a novel endogenous cyclic dipeptide cyclo-prolylglycine…”
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5
Design of N-Acylprolyltyrosine “Tripeptoid” Analogues of Neurotensin as Potential Atypical Antipsychotic Agents
Published in Journal of medicinal chemistry (29-01-1998)“…A series of N-acylprolyltyrosine amides was designed as tripeptoid analogues of neurotensin. The substituted dipeptides were tested in vivo for antidopamine…”
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6
Memory restoring and neuroprotective effects of the proline-containing dipeptide, GVS-111, in a photochemical stroke model
Published in Behavioural pharmacology (01-09-1999)“…Local thrombosis of the frontal cortex (Fr1 and Fr3 fields), caused by combination of the intravenous photosensitive dye Rose Bengal administration with…”
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7
Discriminative Effects of Phenazepam and Gidazepam in Rats: Comparison With Other GABA-Related Drugs
Published in Pharmacology, biochemistry and behavior (01-10-1999)“…The present study assessed the discriminative stimulus effects of phenazepam (PHZ) (2 mg/kg, IP), gidazepam (GDZ) (10 mg/kg, IP), pentobarbital (PB) (10 mg/kg,…”
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8
Designing nootropic dipeptides using an evolutionary-genetic approach
Published in Pharmaceutical chemistry journal (01-01-2006)“…A novel approach to the search for the new groups of biologically active peptides is developed, which is based on the selection of point mutants with respect…”
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9
Neuroprotective activity of proproten in rats with experimental local photothrombosis of the prefrontal cortex
Published in Bulletin of experimental biology and medicine (01-04-2005)“…Proproten (ultralow doses of antibodies to S100 protein) exhibited neuroprotective activity in rats with experimental photochemical thrombosis of the…”
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10
Neuromodulatory mechanism underlying the effect of the atypical dipeptide neuroleptic dilept
Published in Bulletin of experimental biology and medicine (01-11-2003)“…We studied the effects of a new dipeptide neuroleptic Dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) on activity of neurotransmitter systems in the brain…”
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11
Functional brain activity in patients with Parkinson's disease during amantadin-sulfate therapy
Published in Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2005)“…An investigation of bioelectrical brain activity in 32 patients with akinetic-rigid and trembling-rigid forms of Parkinson's disease was conducted before and…”
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12
Comparison of Antipsychotic Activity and Discriminative Stimulus Effects of the Novel Acylprolyltyrosine Containing Compound, GZR-123, and Sulpiride
Published in Pharmacology, biochemistry and behavior (01-10-1999)“…ASMAKOVA L. S., T. S. KALININA, R. U. OSTROVSKAYA, T. A. GUDASHEVA, N. I. ZAITSEVA,N. A. BONDARENKO, T. A. VORONONA, AND S. B. SEREDENIN. Comparison of…”
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13
Effect of Neurotensin Peptidomimetics on Thermoregulation in Rats
Published in Biology bulletin of the Russian Academy of Sciences (01-07-2004)“…The effects of the tripeptide analogues of neurotensin, GZR123 and GZR125, on thermoregulation was studied in rats that were kept at different ambient…”
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14
Crystal and Molecular Structure of 1-(p-Tolyl)-4-[4-(N-naphthalimido)butyl]piperazine
Published in Journal of structural chemistry (01-05-2003)Get full text
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15
TRH mimetics: Differentiation of antiamnesic potency from antidepressant effect
Published in Bioorganic & medicinal chemistry (01-11-1997)“…For the purpose of rational modification of the TRH molecule, we were pursuing an approach that consists of two steps: (1) ‘obligatory’ replacement of…”
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16
Proline-containing dipeptide GVS-111 retains nootropic activity after oral administration
Published in Bulletin of experimental biology and medicine (01-10-2001)“…Experiments on rats trained passive avoidance task showed that N-phenyl-acetyl-L-prolyl-glycyl ethyl ester, peptide analog of piracetam (GVS-111, Noopept)…”
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17
Design of a novel cognitive enhancer (8S, 10aS)-8-carbamoyl-1,2,3,6,7,8,9,10a-octahydro-5H,10H-pyrrolo[1,2-a][1,4]diazocin-5,10-dione
Published in Bioorganic & medicinal chemistry letters (05-11-1996)“…A new cognitive enhancer (8S, 10aS)-8-carbamoyl-1,2,3,6,7,8,9,10a-octahydro-5H,10H-pyrrolo[1,2-a][1,4]diazocin-5,10-dione ( 3) has been designed based on the…”
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18
Dependence of the anxiolytic effect of tranquilizers on the level of anxiety in a conflict situation
Published in Bulletin of experimental biology and medicine (01-01-1996)Get full text
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19
The novel substituted acylproline-containing dipeptide, GVS-111, promotes the restoration of learning and memory impaired by bilateral frontal lobectomy in rats
Published in Behavioural pharmacology (01-06-1997)“…The present study investigated the potential benefit of the ethyl ester of N-phenylacetylprolylglycine (GVS-111) on the model of bilateral frontal lobectomy…”
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20
New endogenous dipeptide cycloprolyl-glycine is similar to piracetam by its mnemotropic selectivity
Published in Bulletin of experimental biology and medicine (01-10-1999)“…The effects of endogenous dipeptide cycloprolyl-glycine on learning and memory in the model of postconvulsive retrograde amnesia of passive avoidance response…”
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