Search Results - "Vorobyov, Andrew"
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A Strategy for Modulation of Enzymes in the Ubiquitin System
Published in Science (American Association for the Advancement of Science) (01-02-2013)“…The ubiquitin system regulates virtually all aspects of cellular function. We report a method to target the myriad enzymes that govern ubiquitination of…”
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Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine
Published in Frontiers in cell and developmental biology (31-03-2020)“…Short linear motifs (SLiMs) located in disordered regions of multidomain proteins are important for the organization of protein-protein interaction networks…”
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Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency
Published in Nature biotechnology (01-01-2018)“…Modulation of DNA repair pathway choice by a potent inhibitor of 53BP1 improves the efficiency of homology-dependent genome editing in human and mouse cells…”
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