Search Results - "Vornicova, Olga"

Pembrolizumab Monotherapy for Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Arm Phase II Trial (KEYNOTE-629) by Grob, Jean-Jacques, Gonzalez, Rene, Basset-Seguin, Nicole, Vornicova, Olga, Schachter, Jacob, Joshi, Abhishek, Meyer, Nicolas, Grange, Florent, Piulats, Josep M, Bauman, Jessica R, Zhang, Pingye, Gumuscu, Burak, Swaby, Ramona F, Hughes, Brett G M

“…Treatment options are limited for patients with recurrent and/or metastatic (R/M) cutaneous squamous cell carcinoma (cSCC); mortality rates exceed 70% in…”
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Shaping the Future of Immunotherapy Targets and Biomarkers in Melanoma and Non-Melanoma Cutaneous Cancers by Spiliopoulou, Pavlina, Vornicova, Olga, Genta, Sofia, Spreafico, Anna

“…Recent advances in treating cutaneous melanoma have resulted in impressive patient survival gains. Refinement of disease staging and accurate patient risk…”
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The perception of Israeli oncology staff members regarding advance care planning by Bar-Sela, Gil, Bagon, Shlomit, Mitnik, Inbal, Baziliansky, Svetlana, Bar-Sella, Avigail, Vornicova, Olga, Tzuk-Shina, Tzahala

“…Background Advance care planning (ACP) defines end-of-life care in accordance with the patients’ preferences. It is highly important during mental and/or…”
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Nuclear localization of heparanase 2 (Hpa2) attenuates breast carcinoma growth and metastasis by Hilwi, Maram, Shulman, Katherina, Naroditsky, Inna, Feld, Sari, Gross-Cohen, Miriam, Boyango, Ilanit, Soboh, Soaad, Vornicova, Olga, Farhoud, Malik, Singh, Preeti, Bar-Sela, Gil, Goldberg, Hadassah, Götte, Martin, Sharrocks, Andrew D., Li, Yaoyong, Sanderson, Ralph D., Ilan, Neta, Vlodavsky, Israel

“…Unlike the intense research effort devoted to exploring the significance of heparanase in cancer, very little attention was given to Hpa2, a close homolog of…”
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Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT) by Genta, Sofia, Lajkosz, Katherine, Yee, Noelle R, Spiliopoulou, Pavlina, Heirali, Alya, Hansen, Aaron R, Siu, Lillian L, Saibil, Sam, Stayner, Lee-Anne, Yanekina, Maryia, Sauder, Maxwell B, Keshavarzi, Sareh, Salawu, Abdulazeez, Vornicova, Olga, Butler, Marcus O, Bedard, Philippe L, Razak, Albiruni R. Abdul, Rottapel, Robert, Chruscinski, Andrzej, Coburn, Bryan, Spreafico, Anna

“…Abstract Background Immune-checkpoint inhibitors (ICI) can lead to immune-related adverse events (irAEs) in a significant proportion of patients. The…”
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Investigational therapies for Ewing sarcoma: a search without a clear finding by Vornicova, Olga, Bar-Sela, Gil

“…Ewing sarcoma family tumors (ESFT) are a group of aggressive diseases, characterized histologically by small, round, blue cells and genetically by…”
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Synergistic activity of PARP inhibitors (PARPi) in combination with standard chemotherapy (CTx) in leiomyosarcoma by Vornicova, Olga, Babichev, Yael, Al-awar, Rima, Marcellus, Richard, Abdul Razak, Albiruni Ryan, Gladdy, Rebecca Anne

“…11560 Background: Leiomyosarcomas (LMS) are genetically heterogeneous tumors that arise from smooth muscle. Currently, the mainstay of systemic treatment for…”
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Do we have a "game changer" in treating patients with brain metastasis from renal cell carcinoma? by Vornicova, Olga, Bar-Sela, Gil

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A pilot study of first-line olaratumab, doxorubicin and ifosfamide in patients with metastatic soft tissue sarcoma by Vornicova, Olga, Haim, Nissim, Bar-Sela, Gil

“…Introduction Olaratumab (O) is a monoclonal antibody that specifically binds PDGFRα. The addition of O to doxorubicin (D) has been approved by the regulatory…”
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Cannabis for Vismodegib-Related Muscle Cramps in a Patient With Advanced Basal Cell Carcinoma by Kutiel, Talia Shentzer, Vornicova, Olga, Bar-Sela, Gil

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Metronomic dosing of selinexor in select soft tissue sarcomas (STS) by Alshibany, Aisha, Salawu, Abdulazeez, Gupta, Abha A., Al-Ezzi, Esmail Mutahar, Genta, Sofia, Malone, Eoghan Ruadh, Watson, Geoffrey Alan, Vornicova, Olga, Wang, Lisa, Arones, Limore, Phillips, Madeline J., Lee, Jasmine, Abdul Razak, Albiruni Ryan

“…11557 Background: Selinexor (S) is a first-in-class, oral, selective inhibitor of nuclear export (SINE). S has a demonstrated anti-tumor activity in STS…”
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Phase 1b study of weekly split-dose selinexor in soft tissue sarcoma (STS) by Salawu, Abdulazeez, Gupta, Abha A., Al-Ezzi, Esmail Mutahar, Genta, Sofia, Malone, Eoghan Ruadh, Vora, Tushar Shailesh, Watson, Geoffrey Alan, Vornicova, Olga, Wang, Lisa, Arones, Limore, Phillips, Madeline J., Lee, Jasmine, Abdul Razak, Albiruni Ryan

“…11563 Background: Selinexor has demonstrated clinical activity in a variety of tumors including STS. Selinexor dosing at 60mg twice a week or 80mg once a week…”
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Leveraging personalized circulating tumor DNA (ctDNA) for detection and monitoring of molecular residual disease in high-risk melanoma by Genta, Sofia, Araujo, Daniel Vilarim, Keshavarzi, Sareh, Pimentel Muniz, Thiago, Saeed Kamil, Zaid, Howarth, Karen, Terrell, Samantha, Joad, Andy, Ventura, Robert, Covelli, Andrea, Saibil, Samuel, Spiliopoulou, Pavlina, Vornicova, Olga, Easson, Alexandra Maria, Butler, Marcus O., Siu, Lillian L., Bratman, Scott Victor, Spreafico, Anna

“…9579 Background: High-risk melanoma has variable prognosis. Adjuvant immuno- (IO) and targeted therapy (TT) are approved for stage III-IV resected disease…”
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Customized autoantibodies (autoAbs) profiling to predict and monitor immune-related adverse events (irAEs) in patients receiving immune checkpoint inhibitors (ICI) by Genta, Sofia, Keshavarzi, Sareh, Yee, Noelle, Heirali, Alya, Hansen, Aaron Richard, Siu, Lillian L., Saibil, Samuel, Stayner, Lee-Anne, Yanekina, Maryia, Sauder, Maxwell, Salawu, Abdulazeez, Spiliopoulou, Pavlina, Vornicova, Olga, Vilbert, Maysa Tamara Silveira, Butler, Marcus O., Bedard, Philippe L., Abdul Razak, Albiruni Ryan, Coburn, Bryan, Chruscinski, Andrzej, Spreafico, Anna

“…2528 Background: Using a customized microarray, we previously reported that patients (pts) who develop irAEs grade (G)≥2 and those who do not, have different…”
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Leiomyosarcoma: Current Clinical Management and Future Horizons by Devaud, Nicolas, Vornicova, Olga, Abdul Razak, Albiruni R, Khalili, Korosh, Demicco, Elizabeth G, Mitric, Cristina, Bernardini, Marcus Q, Gladdy, Rebecca A

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Leiomyosarcoma by Devaud, Nicolas, Vornicova, Olga, Abdul Razak, Albiruni R., Khalili, Korosh, Demicco, Elizabeth G., Mitric, Cristina, Bernardini, Marcus Q., Gladdy, Rebecca A.

“…Leiomyosarcomas are soft tissue tumors that are derived from smooth muscle mainly in the pelvis and retroperitoneum. Percutaneous biopsy is paramount to…”
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Ectopic Cushing's syndrome in a patient with metastatic Merkel cell carcinoma: A case report by Ishay, Avraham, Touma, Elia, Vornicova, Olga, Dodiuk-Gad, Roni, Goldman, Tal, Bisharat, Naiel

“…Ectopic Cushing syndrome (ECS) is a rare condition commonly associated with neuroendocrine tumors (NET), mainly bronchial carcinoids. The association of…”
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The impact of multimodality therapies in marginally inoperable soft tissue sarcomas (STS): The Toronto Sarcoma Program (TSP) experience by Vornicova, Olga, Wunder, Jay, Chung, Peter W. M., Gupta, Abha A., Gladdy, Rebecca Anne, Catton, Charles N., Salah, Samer, Ferguson, Peter Charles, Tsoi, Kim, Shultz, David Benjamin, Brar, Savtaj Singh, Wong, Philip, Swallow, Carol Jane, Abdul Razak, Albiruni Ryan, Al-Ezzi, Esmail Mutahar

“…Abstract only 11548 Background: The mainstay therapy of operable STS remains surgery, which may include (neo)adjuvant therapies. Within the TSP, marginally…”
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Treatment of Metastatic Extramammary Paget's Disease Associated With Adnexal Adenocarcinoma, With Anti‐HER2 Drugs Based on Genomic Alteration ERBB2 S310F by Vornicova, Olga, Hershkovitz, Dov, Yablonski‐Peretz, Tamar, Ben‐Itzhak, Ofer, Keidar, Zohar, Bar‐Sela, Gil

“…Extramammary Paget's disease is a rare intraepithelial malignant condition affecting the apocrine gland‐bearing skin. In this case, a genomic alteration, ERBB2…”
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Prognostic significance of heparanase expression in primary and metastatic breast carcinoma by Vornicova, Olga, Naroditsky, Inna, Boyango, Ilanit, Shachar, Shlomit S, Mashiach, Tanya, Ilan, Neta, Vlodavsky, Israel, Bar-Sela, Gil

“…High levels of heparanase are detected in many types of tumors, associated with bad prognosis. Typically, heparanase levels are evaluated in a biopsy taken…”
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