Search Results - "Vorlícková, Michaela"

8‐Oxoguanine in a quadruplex of the human telomere DNA sequence by Vorlícková, Michaela, Tomasko, Martin, Sagi, Andras J., Bednarova, Klara, Sagi, Janos

“…8‐Oxoguanine is a ubiquitous oxidative base lesion. We report here on the effect of this lesion on the structure and stability of quadruplexes formed by the…”
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Quadruplexes of human telomere dG(3)(TTAG(3))(3) sequences containing guanine abasic sites by Skoláková, Petra, Bednárová, Klára, Vorlícková, Michaela, Sagi, Janos

“…This study was performed to evaluate how the loss of a guanine base affects the structure and stability of the three-tetrad G-quadruplex of…”
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Substitution of adenine for guanine in the quadruplex-forming human telomere DNA sequence G(3)(T(2)AG(3))(3) by Tomasko, Martin, Vorlícková, Michaela, Sagi, Janos

“…We have studied the formation and structural properties of quadruplexes of the human telomeric DNA sequence G(3)(T(2)AG(3))(3) and related sequences in which…”
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Ethanol is a better inducer of DNA guanine tetraplexes than potassium cations by Vorlíčková, Michaela, Bednářová, Klára, Kypr, Jaroslav

“…Guanine tetraplexes are a biologically relevant alternative of the Watson and Crick duplex of DNA. It is thought that potassium or other cations present in the…”
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The thrombin binding aptamer GGTTGGTGTGGTTGG forms a bimolecular guanine tetraplex by Fialová, Markéta, Kypr, Jaroslav, Vorlíčková, Michaela

“…In the literature, the thrombin binding aptamer GGTTGGTGTGGTTGG is generally taken as a prototype of an intramolecular guanine tetraplex of DNA. Our results,…”
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Quadruplexes of human telomere DNA analogs designed to contain G:A:G:A, G:G:A:A, and A:A:A:A tetrads by Sagi, Janos, Renčiuk, Daniel, Tomaško, Martin, Vorlíčková, Michaela

“…Replacement of two to four guanines by adenines in the human telomere DNA repeat dG3(TTAG3)3 did not hinder the formation of quadruplexes if the substitutions…”
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Circular dichroism spectroscopy reveals invariant conformation of guanine runs in DNA by Kypr, Jaroslav, Vorlíčková, Michaela

“…We demonstrate that the characteristic circular dichroism (CD) features of the parallel‐stranded DNA tetraplex of d(G4), especially the strong band at 260 nm,…”
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Quadruplex-forming properties of FRAXA (CGG) repeats interrupted by (AGG) triplets by Renčiuk, Daniel, Zemánek, Michal, Kejnovská, Iva, Vorlíčková, Michaela

“…The (CGG) repeats associated with X-chromosome fragility are generally believed to form quadruplexes. This notion has persisted although it had been shown that…”
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Oligo(dT) is not a correct native PAGE marker for single-stranded DNA by Kejnovská, Iva, Kypr, Jaroslav, Vorlíčková, Michaela

“…Polyacrylamide gel electrophoresis is a widely used method to study short DNA fragments in solution. It is, however, a relative method requiring length markers…”
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Circular dichroism and conformational polymorphism of DNA by Kypr, Jaroslav, Kejnovská, Iva, Renčiuk, Daniel, Vorlíčková, Michaela

“…Here we review studies that provided important information about conformational properties of DNA using circular dichroic (CD) spectroscopy. The conformational…”
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Circular Dichroism Spectroscopy of DNA: From Duplexes to Quadruplexes by Vorlíčková, Michaela, Kejnovská, Iva, Bednářová, Klára, Renčiuk, Daniel, Kypr, Jaroslav

“…ABSTRACT Nucleic acids bear the genetic information and participate in its expression and evolution during replication, repair, recombination, transcription,…”
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Circular dichroism and guanine quadruplexes by Vorlíčková, Michaela, Kejnovská, Iva, Sagi, Janos, Renčiuk, Daniel, Bednářová, Klára, Motlová, Jitka, Kypr, Jaroslav

“…Circular dichroism (CD) is remarkably sensitive to the conformational states of nucleic acids; therefore, CD spectroscopy has been used to study most features…”
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Conformations of DNA strands containing GAGT, GACA, or GAGC tetranucleotide repeats by Kypr, Jaroslav, Kejnovská, Iva, Vorlíčková, Michaela

“…The (GA)n microsatellite has been known from previous studies to adopt unusual, ordered, cooperatively melting secondary structures in neutral aqueous…”
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Systematic investigation of sequence requirements for DNA i-motif formation by Školáková, Petra, Renčiuk, Daniel, Palacký, Jan, Krafčík, Daniel, Dvořáková, Zuzana, Kejnovská, Iva, Bednářová, Klára, Vorlíčková, Michaela

“…Abstract The formation of intercalated motifs (iMs) - secondary DNA structures based on hemiprotonated C.C+ pairs in suitable cytosine-rich DNA sequences, is…”
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CD Study of the G-Quadruplex Conformation by Kejnovská, Iva, Renčiuk, Daniel, Palacký, Jan, Vorlíčková, Michaela

“…Circular Dichroic (CD) spectroscopy is one of the most frequently used methods for guanine quadruplex studies and in general for studies of conformational…”
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Guanine quadruplex formation by RNA/DNA hybrid analogs of Oxytricha telomere G(4)T(4)G(4) fragment by Vondrusková, Jitka, Kypr, Jaroslav, Kejnovská, Iva, Fialová, Markéta, Vorlícková, Michaela

“…Using circular dichroism spectroscopy, gel electrophoresis, and ultraviolet absorption spectroscopy, we have studied quadruplex folding of RNA/DNA analogs of…”
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Role of loops in the guanine quadruplex formation by DNA/RNA hybrid analogs of G4T4G4 by Vondrusková, Jitka, Kypr, Jaroslav, Kejnovská, Iva, Fialová, Markéta, Vorlícková, Michaela

“…CD spectroscopy, gel electrophoresis and absorption-based thermal stability were used to analyze quadruplex formation of RNA and RNA/DNA hybrid analogs of the…”
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Crystal structures of B-DNA dodecamer containing the epigenetic modifications 5-hydroxymethylcytosine or 5-methylcytosine by Renciuk, Daniel, Blacque, Olivier, Vorlickova, Michaela, Spingler, Bernhard

“…5-Hydroxymethylcytosine (5-hmC) was recently identified as a relatively frequent base in eukaryotic genomes. Its physiological function is still unclear, but…”
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i-Motif of cytosine-rich human telomere DNA fragments containing natural base lesions by Dvořáková, Zuzana, Renčiuk, Daniel, Kejnovská, Iva, Školáková, Petra, Bednářová, Klára, Sagi, Janos, Vorlíčková, Michaela

“…Abstract i-Motif (iM) is a four stranded DNA structure formed by cytosine-rich sequences, which are often present in functionally important parts of the genome…”
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Polymorphism of human telomeric quadruplex structure controlled by DNA concentration: a Raman study by Palacky, Jan, Vorlickova, Michaela, Kejnovska, Iva, Mojzes, Peter

“…DNA concentration has been recently suggested to be the reason why different arrangements are revealed for K(+)-stabilized human telomere quadruplexes by…”
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