Potential applications of DNA microarrays in biodefense-related diagnostics

Potential applications of DNA microarrays in biodefense-related diagnostics

Recent years have witnessed a logarithmic growth in the number of applications involving DNA microarrays. Extrapolation of their use for infectious diagnostics and biodefense-related diagnostics seems obvious. Nevertheless, the application of DNA microarrays to biodefense-related diagnostics will de...

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Bibliographic Details
Published in:Current Opinion in Biotechnology Vol. 13; no. 3; pp. 208 - 212
Main Authors: Stenger, David A, Andreadis, Joanne D, Voraa, Gary J, Pancrazio, Joseph J
Format: Book Review Journal Article
Language:English
Published: England Elsevier Ltd 01-06-2002
Subjects:
biodefense
bioinformatics
Bioterrorism
DNA microarray
DNA, Bacterial - classification
DNA, Bacterial - genetics
DNA, Viral - classification
DNA, Viral - genetics
Environmental Microbiology
Environmental Monitoring - instrumentation
Environmental Monitoring - methods
Gene Expression Profiling - instrumentation
host expression profiling
Humans
infectious diagnostics
Oligonucleotide Array Sequence Analysis - classification
Oligonucleotide Array Sequence Analysis - instrumentation
Oligonucleotide Array Sequence Analysis - methods
Oligonucleotide Array Sequence Analysis - trends
pathogen identification
DNA microarray
Biotechnology
pathogen identification
Microbiology
Techniques & Methods
host expression profiling
bioinformatics
infectious diagnostics
Ecology
biodefense
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Summary:Recent years have witnessed a logarithmic growth in the number of applications involving DNA microarrays. Extrapolation of their use for infectious diagnostics and biodefense-related diagnostics seems obvious. Nevertheless, the application of DNA microarrays to biodefense-related diagnostics will depend on solving a set of substantial, yet approachable, technical and logistical problems that encompass diverse topics from amplification efficiency to bioinformatics. The threat presented by potential agents of biological warfare has fueled interest in the development of sensitive and rapid detection technologies for the identification of pathogenic microorganisms and toxins in the environment. Microarray technologies are being developed for such detection purposes.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-3
content type line 23
ISSN:0958-1669
1879-0429
DOI:10.1016/S0958-1669(02)00321-X