Search Results - "Voos, Katrin"
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Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
Published in ACS central science (27-12-2023)“…Infections caused by the Gram-negative pathogen Pseudomonas aeruginosa are emerging worldwide as a major threat to human health. Conventional antibiotic…”
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Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH)
Published in ChemMedChem (20-04-2021)“…Microbial infections are a significant threat to public health, and resistance is on the rise, so new antibiotics with novel modes of action are urgently…”
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Discovery of a Potent Inhibitor Class with High Selectivity toward Clostridial Collagenases
Published in Journal of the American Chemical Society (13-09-2017)“…Secreted virulence factors like bacterial collagenases are conceptually attractive targets for fighting microbial infections. However, previous attempts to…”
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Front Cover: Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH) (ChemMedChem 8/2021)
Published in ChemMedChem (20-04-2021)“…The Front Cover shows work on inhibitors of bacterial collagenases. The inhibition of these virulence factors would reduce bacterial pathogenicity, thus…”
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N -Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosa
Published in RSC medicinal chemistry (20-10-2021)“…Increasing antimicrobial resistance is evolving to be one of the major threats to public health. To reduce the selection pressure and thus to avoid a fast…”
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Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from
Published in RSC medicinal chemistry (20-10-2021)“…Increasing antimicrobial resistance is evolving to be one of the major threats to public health. To reduce the selection pressure and thus to avoid a fast…”
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Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin‐Wound Infections
Published in Advanced therapeutics (01-03-2022)“…Despite the progress in surgical techniques and antibiotic prophylaxis, opportunistic wound infections with Bacillus cereus remain a public health problem…”
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