Search Results - "Vooght, Vanessa De"

TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells by Alpizar, Yeranddy A., Boonen, Brett, Sanchez, Alicia, Jung, Carole, López-Requena, Alejandro, Naert, Robbe, Steelant, Brecht, Luyts, Katrien, Plata, Cristina, De Vooght, Vanessa, Vanoirbeek, Jeroen A. J., Meseguer, Victor M., Voets, Thomas, Alvarez, Julio L., Hellings, Peter W., Hoet, Peter H. M., Nemery, Benoit, Valverde, Miguel A., Talavera, Karel

“…Lipopolysaccharides (LPS), the major components of the wall of gram-negative bacteria, trigger powerful defensive responses in the airways via mechanisms…”
Get full text

Repeated invasive lung function measurements in intubated mice: an approach for longitudinal lung research by Vleeschauwer, Stéphanie I. de, Rinaldi, Manuela, Vooght, Vanessa de, Vanoirbeek, Jeroen A, Vanaudenaerde, Bart M, Verbeken, Erik K, Decramer, Marc, Gayan-Ramirez, Ghislaine N, Verleden, Geert M, Janssens, Wim

“…Invasive lung function measurements are useful tools to describe respiratory disease models in mice but only result in one time-point measurements because of…”
Get full text

Nano-titanium dioxide modulates the dermal sensitization potency of DNCB by Hussain, Salik, Smulders, Stijn, De Vooght, Vanessa, Ectors, Bert, Boland, Sonja, Marano, Francelyne, Van Landuyt, Kirsten L, Nemery, Benoit, Hoet, Peter H M, Vanoirbeek, Jeroen A J

“…We determined the ability of a model nanoparticle (NP) (titanium dioxide, TiO(2)) to modulate sensitization induced by a known potent dermal sensitizer…”
Get full text

Noninvasive and Invasive Pulmonary Function in Mouse Models of Obstructive and Restrictive Respiratory Diseases by Vanoirbeek, Jeroen A. J, Rinaldi, Manuela, De Vooght, Vanessa, Haenen, Steven, Bobic, Sonja, Gayan-Ramirez, Ghislaine, Hoet, Peter H. M, Verbeken, Erik, Decramer, Marc, Nemery, Benoit, Janssens, Wim

“…Pulmonary function analysis is an important tool in the evaluation of mouse respiratory disease models, but much controversy still exists on the validity of…”
Get full text

Crucial Role of Transient Receptor Potential Ankyrin 1 and Mast Cells in Induction of Nonallergic Airway Hyperreactivity in Mice by HOX, Valérie, VANOIRBEEK, Jeroen A, LISTON, Adrian, VOETS, Thomas, VENNEKENS, Rudi, BULLENS, Dominique M. A, DE VRIES, Annick, HOET, Peter, BRAUN, Armin, CEUPPENS, Jan L, TALAVERA, Karel, NEMERY, Benoit, ALPIZAR, Yeranddy A, HELLINGS, Peter W, VOEDISCH, Sabrina, CALLEBAUT, Ina, BOBIC, Sonja, SHARIFY, Ali, DE VOOGHT, Vanessa, VAN GERVEN, Laura, DEVOS, Fien

“…Airway hyperreactivity (AHR) is a key feature of bronchial asthma, and inhalation of irritants may facilitate development of nonallergic AHR. Swimmers exposed…”
Get full text

Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model by Pollaris, Lore, Devos, Fien, De Vooght, Vanessa, Seys, Sven, Nemery, Benoit, Hoet, Peter H. M., Vanoirbeek, Jeroen A. J.

“…Both 2,4-toluene diisocyanate (TDI) and 4,4-methylene diphenyl diisocyanate (MDI) can cause occupational asthma. In this study, we optimized our mouse model of…”
Get full text

Choice of mouse strain influences the outcome in a mouse model of chemical-induced asthma by De Vooght, Vanessa, Vanoirbeek, Jeroen A J, Luyts, Katrien, Haenen, Steven, Nemery, Benoit, Hoet, Peter H M

“…The development of occupational asthma is the result of interactions between environmental factors and individual susceptibility. We assessed how our model of…”
Get full text

B-lymphocytes as key players in chemical-induced asthma by De Vooght, Vanessa, Carlier, Vincent, Devos, Fien C, Haenen, Steven, Verbeken, Erik, Nemery, Benoit, Hoet, Peter H M, Vanoirbeek, Jeroen A J

“…T-lymphocytes and B-lymphocytes are key players in allergic asthma, with B-lymphocytes producing antigen-specific immunoglobulins E (IgE). We used a mouse…”
Get full text

Oropharyngeal aspiration: An alternative route for challenging in a mouse model of chemical-induced asthma by De Vooght, Vanessa, Vanoirbeek, Jeroen A.J, Haenen, Steven, Verbeken, Erik, Nemery, Benoit, Hoet, Peter H.M

“…Abstract Background To assess the importance of the route of challenge in an existing mouse model of chemical-induced asthma, we replaced intranasal…”
Get full text

Neutrophil and eosinophil granulocytes as key players in a mouse model of chemical-induced asthma by De Vooght, Vanessa, Smulders, Stijn, Haenen, Steven, Belmans, Jochen, Opdenakker, Ghislain, Verbeken, Erik, Nemery, Benoit, Hoet, Peter H M, Vanoirbeek, Jeroen A J

“…Diisocyanates are an important cause of chemical-induced occupational asthma. This type of immunologically mediated asthma is often characterized by a…”
Get full text

Proteomic Alterations in B Lymphocytes of Sensitized Mice in a Model of Chemical-Induced Asthma by Haenen, Steven, Vanoirbeek, Jeroen A J, De Vooght, Vanessa, Schoofs, Liliane, Nemery, Benoit, Clynen, Elke, Hoet, Peter H M

“…The role of B-lymphocytes in chemical-induced asthma is largely unknown. Recent work demonstrated that transferring B lymphocytes from toluene diisocyanate…”
Get full text

Placental growth factor contributes to bronchial neutrophilic inflammation and edema in allergic asthma by Bobic, Sonja, Seys, Sven, De Vooght, Vanessa, Callebaut, Ina, Hox, Valerie, Dooms, Christophe, Vinckier, Stefan, Jonckx, Bart, Saint-Remy, Jean-Marie, Stassen, Jean-Marie, Bullens, Dominique M A, Ceuppens, Jan L, Carmeliet, Peter, Hellings, Peter W

“…Placental growth factor (PlGF) and its receptor vascular endothelial growth factor receptor 1 (VEGFR1) play an important role in pathological conditions…”
Get full text

Immunological determinants of ventilatory changes induced in mice by dermal sensitization and respiratory challenge with toluene diisocyanate by Tarkowski, Maciej, Vanoirbeek, Jeroen A J, Vanhooren, Hadewijch M, De Vooght, Vanessa, Mercier, Caroline M, Ceuppens, Jan, Nemery, Benoit, Hoet, Peter H M

“…The objective of the study was to characterize better the immunologic mechanisms underlying a previously developed animal model of chemical-induced asthma…”
Get more information

Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo by De Langhe, Ellen, Aznar-Lopez, Carolina, De Vooght, Vanessa, Vanoirbeek, Jeroen A, Luyten, Frank P, Lories, Rik Ju

“…The pathogenesis of pulmonary fibrosis remains poorly understood. The Wnt signaling pathway regulates fibrogenesis in different organs. Here, we studied the…”
Get full text

Proteome changes in auricular lymph nodes and serum after dermal sensitization to toluene diisocyanate in mice by Haenen, Steven, Clynen, Elke, Vooght, Vanessa De, Schoofs, Liliane, Nemery, Benoit, Hoet, Peter H. M., Vanoirbeek, Jeroen A. J.

“…Some reactive chemicals, such as diisocyanates, are capable of initiating an allergic response, which can lead to occupational asthma after a latency period…”
Get full text

How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice? by Vanoirbeek, Jeroen A.J., PhD, De Vooght, Vanessa, MSc, Vanhooren, Hadewijch M., MSc, Nawrot, Tim S., PhD, Nemery, Benoit, MD, PhD, Hoet, Peter H.M., PhD

“…Background Years after removal from exposure, workers with occupational asthma still show respiratory symptoms and airway hyperresponsiveness on re-exposure to…”
Get full text

Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis by De Langhe, Ellen, Cailotto, Frederic, De Vooght, Vanessa, Aznar-Lopez, Carolina, Vanoirbeek, Jeroen Alfons, Luyten, Frank Prosper, Lories, Rik Jozef Urbain

“…Effective treatments for fibrotic diseases such as idiopathic pulmonary fibrosis are largely lacking. Transforming growth factor beta (TGFβ) plays a central…”
Get full text

Thrombogenic changes in young and old mice upon subchronic exposure to air pollution in an urban roadside tunnel by Emmerechts, Jan, De Vooght, Vanessa, Haenen, Steven, Loyen, Serena, Van kerckhoven, Soetkin, Hemmeryckx, Bianca, Vanoirbeek, Jeroen A J, Hoet, Peter H, Nemery, Ben, Hoylaerts, Marc F

“…Epidemiological studies indicate that elderly persons are particularly susceptible to the cardiovascular health complications of air pollution, but…”
Get more information

Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer by Vanoirbeek, Jeroen A.J., Tarkowski, Maciej, Vanhooren, Hadewijch M., De Vooght, Vanessa, Nemery, Benoit, Hoet, Peter H.M.

“…Occupational asthma can be caused by chemicals. Previously, we established a murine model of immunologically mediated chemical-induced asthma using toluene…”
Get full text

Airway exposure to hypochlorite prior to ovalbumin induces airway hyperreactivity without evidence for allergic sensitization by Hox, Valérie, Vanoirbeek, Jeroen A., Callebaut, Ina, Bobic, Sonja, De Vooght, Vanessa, Ceuppens, Jan, Hoet, Peter, Nemery, Benoit, Hellings, Peter W.

“…Some epidemiologic studies have indicated that attendance to chlorinated swimming pools is associated with airway hyperreactivity (AHR), allergies and asthma…”
Get full text