Search Results - "Vonka, Vladimir"

Prophylactic vaccines against cancers of non-infectious origin: a dream or a real possibility? by Vonka, Vladimír, Hirsch, Ivan

“…The dramatic progress in tumour biology and immunology in the past several years has opened new avenues for the treatment and prevention of cancer. One of the…”
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Immunology of chronic myeloid leukemia: current concepts and future goals by Vonka, Vladimír, Petráčková, Martina

“…Although chronic myeloid leukemia is a rare malignancy, it has developed into a model system for the study of a variety of aspects of cancer biology and…”
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PROFESSOR ERVIN ADAM by Vonka, Vladimír

“…Last November, a few days after his 90th birthday, Dr. Ervin Adam, a member of the Journal Editorial Board and Professor of Epidemiology at Baylor University…”
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Immunotherapy of chronic myeloid leukemia: present state and future prospects by Vonka, Vladimír

“…In spite of the considerable successes that have been achieved in the treatment of chronic myeloid leukemia (CML), cure for the disease can only be obtained by…”
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Comments on therapeutic cancer vaccines by Vonka, Vladimír

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Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony-stimulating factor: I. Derivation, genetic stability, oncogenicity and immunogenicity by PETRACKOVA, Martina, TACHEZY, Ruth, VONKA, Vladimir

“…The highly oncogenic bcr-abl-transformed mouse (Balb/c) 12B1 cells were transfected with plasmids carrying genes for either mouse interleukin-2 (IL‑2) or the…”
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Tumor Protective Activity of CD4+ but Not of CD8+ T Cells in DNA-Vaccinated Mice Challenged with bcr-abl-Transformed Cells by Petráčková, Martina, Vonka, Vladimír, Lučanský, Vincent

“…In the recent past, it has repeatedly been reported that CD4 cells play an important role in the immunology of chronic myeloid leukaemia. It was therefore of…”
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Immunisation with modified HPV16 E7 genes against mouse oncogenic TC-1 cell sublines with downregulated expression of MHC class I molecules by Šmahel, Michal, Šı́ma, Pavel, Ludvı́ková, Viera, Marinov, Iuri, Pokorná, Dana, Vonka, Vladimı́r

“…Human papillomavirus type 16 (HPV16)-transformed mouse TC-1 cells are extensively used in the evaluation of efficacy of experimental vaccines against tumours…”
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Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony stimulating factor (GM-CSF): II. Adverse effects of GM-CSF by PETRACKOVA, Martina, STANEK, Libor, MANDYS, Vaclav, DUNDR, Pavel, VONKA, Vladimír

“…Granulocyte-macrophage colony stimulating factor (GM-CSF) is considered to be the most effective immunostimulating factor for the construction of…”
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Predictive value of serum cytokine levels in chronic myeloid leukemia patients by Petrackova, Martina, Hamsikova, Eva, Duskova, Martina, Ptackova, Pavlina, Klamova, Hana, Humlova, Zuzana, Vonka, Vladimir

“…Highlights • Cytokine levels in CML patients at diagnosis and therapy outcome were related. • MCP-1 levels were significantly higher in patients with optimal…”
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Protein Profiling of Two Mouse BCR-ABL-Transformed Cell Lines by Krmencikova, Monika, Petrackova, Martina, Vonka, Vladimir

“…Abstract 4720 Our efforts aim at the development of effective experimental vaccines against bcr-abl-transformed cells. For our study two mouse (Balb/c)…”
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Unexpected properties of endostatin-producing mouse BCR-ABL-transformed cells by KRMENCIKOVA, Monika, STANEK, Libor, PETRACKOVA, Martina, DUNDR, Pavel, VONKA, Vladimír

“…We investigated whether a genetic modification of BCR-ABL-transformed mouse cells that resulted in endostatin (ES) production altered their oncogenic…”
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Bcr-Abl fusion sequences do not induce immune responses in mice when administered in mouse polyomavirus based virus-like particles by HRUSKOVA, Veronika, MORAVKOVA, Alena, BABIAROVA, Katarina, LUDVIKOVA, Viera, FRIC, Jan, VONKA, Vladimír, FORSTOVA, Jitka

“…Mouse polyomavirus-like particles (MPyV-VLPs) carrying inside a fragment of the Bcr-Abl hybrid protein containing the epitope of chronic myeloid leukemia…”
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Changes of Immunological Profiles in Patients with Chronic Myeloid Leukemia in the Course of Treatment by Hamšíková, Eva, Vonka, Vladimír, Humlová, Zuzana, Roth, Zdeněk, Šterzl, Ivan, Králíková, Petra, Klamová, Hana, Janatková, Ivana, Malíčková, Karin

“…In the previous paper of ours we compared, prior to start any treatment, a number of immunological parameters in 24 chronic myeloid leukemia patients with the…”
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Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells : An in vitro study by SMETANA, Karel, DVORANKOVA, Barbora, LACINA, Lukas, CADA, Zdenek, VONKA, Vladimir

“…The role of stem cells in cancer formation and spreading has been established. As with normal tissue, the cancer stem cells need a special microenvironment to…”
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Intracellular Cytokines Produced by Stimulated CD3+ Cells from Chronic Myeloid Leukemia Patients by Ptackova, Pavlina, Petrackova, Martina, Hindos, Miroslav, Duskova, Martina, Hamsikova, Eva, Klamova, Hana, Pecherkova, Pavla, Humlova, Zuzana, Vonka, Vladimir

“…Our work examined the production of intracellular interferon (INF)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-2, and IL-4 by in vitro stimulated CD3+…”
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VACCINES AGAINST HUMAN PAPILLOMAVIRUSES : A MAJOR BREAKTHROUGH IN CANCER PREVENTION by VONKA, Vladimir, HAMSIKOVA, Eva

“…Carcinoma of the cervix (CaCer) is the second most frequent malignancy in women on a global scale. Epidemiological studies carried out at the beginning of the…”
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Causality in medicine: the case of tumours and viruses by Vonka, Vladimír

“…Clarification of the aetiology of chronic human diseases such as atherosclerosis or cancer is one of the dominant topics in contemporary medical research. It…”
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Administration of a plasmid that expresses SDF-1α affects the oncogenic potential of mouse bcr-abl-transformed cells by LUCANSKY, VINCENT, KRMENCIKOVA-FLIEGL, MONIKA, STANEK, LIBOR, VONKA, VLADIMIR

“…Stromal-derived factor 1α (SDF-1α, also known as CXCL12) is a chemokine that exerts its effects through the G-protein coupled receptors, C-X-C chemokine…”
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Kynurenine and uric acid levels in chronic myeloid leukemia patients by Vonka, Vladimir, Humlova, Zuzana, Klamova, Hana, Kujovska-Krcmova, Lenka, Petrackova, Martina, Hamsikova, Eva, Krmencikova-Fliegl, Monika, Duskova, Martina, Roth, Zdenek

“…Indoleamine 2,3-dioxygenase 1 (IDO1), IDO2 and tryptophan 2,3-dioxygenase (TDO) represent some of the key immune regulators. Their increased activity has been…”
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