Search Results - "Vonk, Lucienne A."

Allogeneic MSCs and Recycled Autologous Chondrons Mixed in a One‐Stage Cartilage Cell Transplantion: A First‐in‐Man Trial in 35 Patients by de Windt, Tommy S., Vonk, Lucienne A., Slaper‐Cortenbach, Ineke C. M., Nizak, Razmara, van Rijen, Mattie H. P., Saris, Daniel B. F.

“…MSCs are known as multipotent mesenchymal stem cells that have been found capable of differentiating into various lineages including cartilage. However, recent…”
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The clinical potential of articular cartilage-derived progenitor cells: a systematic review by Rikkers, Margot, Korpershoek, Jasmijn V., Levato, Riccardo, Malda, Jos, Vonk, Lucienne A.

“…Over the past two decades, evidence has emerged for the existence of a distinct population of endogenous progenitor cells in adult articular cartilage,…”
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Selection of Highly Proliferative and Multipotent Meniscus Progenitors through Differential Adhesion to Fibronectin: A Novel Approach in Meniscus Tissue Engineering by Korpershoek, Jasmijn V., Rikkers, Margot, de Windt, Tommy S., Tryfonidou, Marianna A., Saris, Daniel B. F., Vonk, Lucienne A.

“…Meniscus injuries can be highly debilitating and lead to knee osteoarthritis. Progenitor cells from the meniscus could be a superior cell type for meniscus…”
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Potential of Melt Electrowritten Scaffolds Seeded with Meniscus Cells and Mesenchymal Stromal Cells by Korpershoek, Jasmijn V, Ruijter, Mylène de, Terhaard, Bastiaan F, Hagmeijer, Michella H, Saris, Daniël B F, Castilho, Miguel, Malda, Jos, Vonk, Lucienne A

“…Meniscus injury and meniscectomy are strongly related to osteoarthritis, thus there is a clinical need for meniscus replacement. The purpose of this study is…”
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Intra-articular injection with Autologous Conditioned Plasma does not lead to a clinically relevant improvement of knee osteoarthritis: a prospective case series of 140 patients with 1-year follow-up by Korpershoek, Jasmijn V, Vonk, Lucienne A, De Windt, Tommy S, Admiraal, Jon, Kester, Esmee C, Van Egmond, Nienke, Saris, Daniël B F, Custers, Roel J H

“…Background and purpose - Platelet-rich plasma (PRP) is broadly used in the treatment of knee osteoarthritis, but clinical outcomes are highly variable. We…”
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Enzymatic Isolation of Articular Chondrons: Is It Much Different Than That of Chondrocytes? by van Mourik, Marloes, Schuiringa, Gerke H, Varion-Verhagen, Liesbeth P, Vonk, Lucienne A, van Donkelaar, Corrinus C, Ito, Keita, Foolen, Jasper

“…In native articular cartilage, chondrocytes (Chy) are completely capsulated by a pericellular matrix (PCM), together called the chondron (Chn). Due to its…”
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Mechanically Derived Tissue Stromal Vascular Fraction Acts Anti-inflammatory on TNF Alpha-Stimulated Chondrocytes In Vitro by van Boxtel, Joeri, Vonk, Lucienne A, Stevens, Hieronymus P, van Dongen, Joris A

“…Enzymatically isolated stromal vascular fraction (SVF) has already shown to be effective as a treatment for osteoarthritis (OA). Yet, the use of enzymes for…”
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Effect of collagen type I or type II on chondrogenesis by cultured human articular chondrocytes by Rutgers, Marijn, Saris, Daniel B, Vonk, Lucienne A, van Rijen, Mattie H, Akrum, Vanessa, Langeveld, Danielle, van Boxtel, Antonette, Dhert, Wouter J, Creemers, Laura B

“…Current cartilage repair procedures using autologous chondrocytes rely on a variety of carriers for implantation. Collagen types I and II are frequently used…”
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Concise Review: Unraveling Stem Cell Cocultures in Regenerative Medicine: Which Cell Interactions Steer Cartilage Regeneration and How? by de Windt, Tommy S., Hendriks, Jeanine A.A., Zhao, Xing, Vonk, Lucienne A., Creemers, Laura B., Dhert, Wouter J.A., Randolph, Mark A., Saris, Daniel B.F.

“…This review provides a systematic overview of the literature on stem cell cocultures with cartilage cells and tries to elucidate the mechanisms that lead to…”
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Response to: Mesenchymal Stem Cells: Time to Change the Name by de Windt, Tommy S., Vonk, Lucienne A., Saris, Daniel B.F.

“…According to the Cambridge dictionary, a stem cell is defined as “a cell, especially one taken from a person or animal in a very early stage of development…”
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Cell-Based Meniscus Repair and Regeneration: At the Brink of Clinical Translation? by Korpershoek, Jasmijn V, de Windt Tommy S, Hagmeijer, Michella H, Vonk, Lucienne A, Saris Daniel B F

“…Background:Meniscus damage can be caused by trauma or degeneration and is therefore common among patients of all ages. Repair or regeneration of the menisci…”
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Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro by Vonk, Lucienne A, van Dooremalen, Sanne F J, Liv, Nalan, Klumperman, Judith, Coffer, Paul J, Saris, Daniël B F, Lorenowicz, Magdalena J

“…Osteoarthritis (OA) is a rheumatic disease leading to chronic pain and disability with no effective treatment available. Recently, allogeneic human mesenchymal…”
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Allogeneic Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single‐Stage Cartilage Repair in Humans upon Mixture with Recycled Autologous Chondrons by de Windt, Tommy S., Vonk, Lucienne A., Slaper‐Cortenbach, Ineke C. M., van den Broek, Marcel P. H., Nizak, Razmara, van Rijen, Mattie H. P., de Weger, Roel A., Dhert, Wouter J. A., Saris, Daniel B. F.

“…Traditionally, mesenchymal stem cells (MSCs) isolated from adult bone marrow were described as being capable of differentiating to various lineages including…”
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Five-Year Outcome of 1-Stage Cell-Based Cartilage Repair Using Recycled Autologous Chondrons and Allogenic Mesenchymal Stromal Cells: A First-in-Human Clinical Trial by Saris, Tim F.F., de Windt, Tommy S., Kester, Esmee C., Vonk, Lucienne A., Custers, Roel J.H., Saris, Daniel B.F.

“…Background: Long-term clinical evaluation of patient outcomes can steer treatment choices and further research for cartilage repair. Using mesenchymal stromal…”
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Is Magnetic Resonance Imaging Reliable in Predicting Clinical Outcome After Articular Cartilage Repair of the Knee?: A Systematic Review and Meta-analysis by de Windt, Tommy S., Welsch, Goetz H., Brittberg, Mats, Vonk, Lucienne A., Marlovits, Stefan, Trattnig, Siegfried, Saris, Daniel B.F.

“…Background: While MRI can provide a detailed morphological evaluation after articular cartilage repair, its additional value in determining clinical outcome…”
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Identification and culture of meniscons, meniscus cells with their pericellular matrix by Struijk, Caroline, Korpershoek, Jasmijn, Lydon, Katherine L., Verdonk, Peter, Michielsen, Jozef, Krych, Aaron J., Vonk, Lucienne A., Saris, Daniel B.F.

“…Meniscus injury is highly debilitating and often results in osteoarthritis. Treatment is generally symptomatic; no regenerative treatments are available…”
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Platelet-Rich Plasma Does Not Inhibit Inflammation or Promote Regeneration in Human Osteoarthritic Chondrocytes In Vitro Despite Increased Proliferation by Rikkers, Margot, Dijkstra, Koen, Terhaard, Bastiaan F., Admiraal, Jon, Levato, Riccardo, Malda, Jos, Vonk, Lucienne A.

“…Objective The aims of the study were to assess the anti-inflammatory properties of platelet-rich plasma (PRP) and investigate its regenerative potential in…”
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Single-Stage Cell-Based Cartilage Regeneration Using a Combination of Chondrons and Mesenchymal Stromal Cells: Comparison With Microfracture by Bekkers, Joris E.J., Tsuchida, Anika I., van Rijen, Mattie H.P., Vonk, Lucienne A., Dhert, Wouter J.A., Creemers, Laura B., Saris, Daniel B.F.

“…Background: Autologous chondrocyte implantation (ACI) is traditionally a 2-step procedure used to repair focal articular cartilage lesions. With use of a…”
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Cellular reprogramming for clinical cartilage repair by Driessen, Britta J.H., Logie, Colin, Vonk, Lucienne A.

“…The repair of articular cartilage needs a sufficient number of chondrocytes to replace the defect tissue, and therefore, expansion of cells is generally…”
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Direct Cell-Cell Contact with Chondrocytes Is a Key Mechanism in Multipotent Mesenchymal Stromal Cell-Mediated Chondrogenesis by de Windt, Tommy S, Saris, Daniel B F, Slaper-Cortenbach, Ineke C M, van Rijen, Mattie H P, Gawlitta, Debby, Creemers, Laura B, de Weger, Roel A, Dhert, Wouter J A, Vonk, Lucienne A

“…Using a combination of articular chondrocytes (ACs) and mesenchymal stromal cells (MSCs) has shown to be a viable option for a single-stage cell-based…”
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