Search Results - "Vondrak, Kristen"

Diffusion tensor imaging and myelin composition analysis reveal abnormal myelination in corpus callosum of canine mucopolysaccharidosis I by Provenzale, James M., Nestrasil, Igor, Chen, Steven, Kan, Shih-hsin, Le, Steven Q., Jens, Jacqueline K., Snella, Elizabeth M., Vondrak, Kristen N., Yee, Jennifer K., Vite, Charles H., Elashoff, David, Duan, Lewei, Wang, Raymond Y., Ellinwood, N. Matthew, Guzman, Miguel A., Shapiro, Elsa G., Dickson, Patricia I.

“…Children with mucopolysaccharidosis I (MPS I) develop hyperintense white matter foci on T2-weighted brain magnetic resonance (MR) imaging that are associated…”
Get full text

A Humoral Immune Response Alters the Distribution of Enzyme Replacement Therapy in Murine Mucopolysaccharidosis Type I by Le, Steven Q, Kan, Shih-Hsin, Clarke, Don, Sanghez, Valentina, Egeland, Martin, Vondrak, Kristen N, Doherty, Terence M, Vera, Moin U, Iacovino, Michelina, Cooper, Jonathan D, Sands, Mark S, Dickson, Patricia I

“…Antibodies against recombinant proteins can significantly reduce their effectiveness in unanticipated ways. We evaluated the humoral response of mice with the…”
Get full text

Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB by Kan, Shih-hsin, Aoyagi-Scharber, Mika, Le, Steven Q., Vincelette, Jon, Ohmi, Kazuhiro, Bullens, Sherry, Wendt, Daniel J., Christiansen, Terri M., Tiger, Pascale M. N., Brown, Julian R., Lawrence, Roger, Yip, Bryan K., Holtzinger, John, Bagri, Anil, Crippen-Harmon, Danielle, Vondrak, Kristen N., Chen, Zhi, Hague, Chuck M., Woloszynek, Josh C., Cheung, Diana S., Webster, Katherine A., Adintori, Evan G., Lo, Melanie J., Wong, Wesley, Fitzpatrick, Paul A., LeBowitz, Jonathan H., Crawford, Brett E., Bunting, Stuart, Dickson, Patricia I., Neufeld, Elizabeth F.

“…Significance Mucopolysaccharidosis type IIIB (MPS IIIB) is a devastating and currently untreatable disease affecting mainly the brain. The cause is lack of the…”
Get full text

430. Antibodies to Recombinant Human α-L-Iduronidase Enhance Uptake into Macrophages in Murine Mucopolysaccharidosis Type I by Sanghez, Valentina, Kan, Shih-Hsin, Le, Steven Q, Clarke, Don, Vondrak, Kristen, Vera, Moin U, Iacovino, Michelina, Sands, Mark S, Dickson, Patricia I

Get full text

Characterization on the cellular distribution of enzyme replacement therapy (ERT) under the influence of humoral immune response in MPS I mouse model by Sanghez, Valentina, Kan, Shih-hsin, Le, Steven Q, Clarke, Don, Vondrak, Kristen N, Vera, Moin, Iacovino, Michelina, Sands, Mark, Dickson, Patti

Get full text