Search Results - "Vonderheid, E C"

Safety of a new, single, integrated, closed photopheresis system in patients with cutaneous T-cell lymphoma by Bisaccia, E., Vonderheid, E.C., Geskin, L.

“…Summary Background  Extracorporeal photopheresis (ECP) is an approved palliative treatment for cutaneous T‐cell lymphoma (CTCL). The THERAKOS™ CELLEX™…”
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Early changes in miRNA expression are predictive of response to extracorporeal photopheresis in cutaneous T-cell lymphoma by McGirt, L.Y., Baerenwald, D.A., Vonderheid, E.C., Eischen, C.M.

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BCL2 and JUNB abnormalities in primary cutaneous lymphomas by Mao, X., Orchard, G., Lillington, D.M., Child, F.J., Vonderheid, E.C., Nowell, P.C., Bagot, M., Bensussan, A., Russell-Jones, R., Young, B.D., Whittaker, S.J.

“…Summary Background  BCL2 is upregulated in nodal and extranodal B‐cell non‐Hodgkin's lymphomas, with a consequent antiapoptotic effect. However, loss of BCL2…”
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Interleukin-12 Therapy of Cutaneous T-Cell Lymphoma Induces Lesion Regression and Cytotoxic T-Cell Responses by Rook, Alain H., Wood, Gary S., Yoo, Elisa K., Elenitsas, Rosalie, Kao, David M.F., Sherman, Matthew L., Witmer, William K., Rockwell, Kenneth A., Shane, Ryan B., Lessin, Stuart R., Vonderheid, Eric C.

“…Progression of cutaneous T-cell lymphoma (CTCL) is associated with profound defects in cell-mediated immunity and depressed production of cytokines, which…”
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Differentiation of tumour-stage mycosis fungoides, psoriasis vulgaris and normal controls in a pilot study using serum proteomic analysis by Cowen, E.W., Liu, C-W., Steinberg, S.M., Kang, S., Vonderheid, E.C., Kwak, H.S., Booher, S., Petricoin, E.F., Liotta, L.A., Whiteley, G., Hwang, S.T.

“…Summary Background  Serum proteomic analysis is an analytical technique utilizing high‐throughput mass spectrometry (MS) in order to assay thousands of serum…”
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Activation of Jak/STAT Proteins Involved in Signal Transduction Pathway Mediated by Receptor for Interleukin 2 in Malignant T Lymphocytes Derived from Cutaneous Anaplastic Large T-Cell Lymphoma and Sezary Syndrome by Zhang, Qian, Nowak, Irena, Vonderheid, Eric C., Rook, Alain H., Kadin, Marshall E., Nowell, Peter C., Shaw, Leslie M., Wasik, Mariusz A.

“…Signaling through the interleukin 2 receptor (IL-2R) involves phosphorylation of several proteins including Jak3, STAT5, and, in preactivated cells, STAT3. In…”
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Use of serum soluble interleukin-2 receptor levels to monitor the progression of cutaneous T-cell lymphoma by Vonderheid, Eric C., Zhang, Qian, Lessin, Stuart R., Polansky, Marcia, Abrams, J.Todd, Bigler, Robert D., Wasik, Mariusz A.

“…Background: The serum concentration of soluble a chain of the interleukin-2 receptor (sIL-2R) correlates with tumor burden in cutaneous T-cell lymphoma (CTCL)…”
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Radiotherapy for unilesional mycosis fungoides by Micaily, B, Miyamoto, C, Kantor, G, Lessin, S, Rook, A, Brady, L, Goodman, R, Vonderheid, E C

“…To evaluate the treatment outcome and natural history of patients with the diagnosis of unilesional mycosis fungoides, treated according to a prospective…”
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Genetic markers associated with progression in early mycosis fungoides by Johnson, V.E., Vonderheid, E.C., Hess, A.D., Eischen, C.M., McGirt, L.Y.

“…Background Mycosis fungoides (MF) is a rare, but potentially devastating malignancy. It classically presents with cutaneous patches and plaques and can…”
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Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing by Nagasawa, T., Zhang, Q., Raghunath, P.N., Wong, H.Y., El-Salem, M., Szallasi, A., Marzec, M., Gimotty, P., Rook, A.H., Vonderheid, E.C., Odum, N., Wasik, M.A.

“…To understand better T-cell lymphomagenesis, we examined promoter CpG methylation and mRNA expression of closely related genes encoding p16, p15, and p14 tumor…”
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Aberrant Cytokine Production By Sezary Syndrome Patients: Cytokine Secretion Pattern Resembles Murine Th2 Cells by Vowels, Benjamin R, Cassin, Maureen, Vonderheid, Eric C, Rook, Alain H

“…Sezary syndrome (SzS), the leukemic stage of cutaneous T-cell lymphoma (CTCL), is typically a CD4+ T-cell lympho-proliferative disease characterized by…”
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Cutaneous T-cell lymphoma in association with silicone breast implants by Duvic, Madeleine, Moore, Dennis, Menter, Alan, Vonderheid, Eric C

“…Background: Cutaneous T-cell lymphoma (CTCL) is a chronic malignancy of helper T cells with the CD4 phenotype. It occurs less frequently in young women but is…”
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p53 tumor suppressor gene mutations in transformed cutaneous T-cell lymphoma: A study of 12 cases by Marrogi, A. J., Khan, M. A., Vonderheid, E. C., Wood, G. S., McBurney, E.

“…The transformation of cutaneous T‐cell lymphoma (t‐CTCL) is an uncommon phenomenon that is associated with histopathologic changes and follows an aggressive…”
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Fine-needle aspiration biopsy in the evaluation of lymphadenopathy associated with cutaneous T-cell lymphoma (mycosis fungoides/Sézary syndrome) by Galindo, L M, Garcia, F U, Hanau, C A, Lessin, S R, Jhala, N, Bigler, R D, Vonderheid, E C

“…We studied the role of fine-needle aspiration (FNA) in the evaluation of lymphadenopathy associated with cutaneous T-cell lymphoma (CTCL) in 11 patients with…”
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Cutaneous T cell lymphoma with suppressor/cytotoxic (CD8) phenotype: identification of rapidly progressive and chronic subtypes by Agnarsson, B A, Vonderheid, E C, Kadin, M E

“…We identified nine patients with cutaneous T cell lymphoma in whom the neoplastic cells expressed the CD8 (T8) suppressor T cell phenotype instead of the more…”
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Localized cutaneous amyloidosis associated with mycosis fungoides by Romero, Laura S., Kantor, Gary R., Levin, Marc W., Vonderheid, Eric C.

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Sarcoidal tissue reaction in Sézary syndrome by Gregg, Patrick J., Kantor, Gary R., Telang, Gladys Hines, Lessin, Stuart R., Nowell, Peter C., Vonderheid, Eric C.

“…Sézary syndrome (SS) is an erythrodermic and leukemic variant of cutaneous T-cell lymphoma (CTCL). Occasionally, the histology of CTCL exhibits evidence of a…”
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Autologous bone marrow transplantation for advanced stage mycosis fungoides by Bigler, R D, Crilley, P, Micaily, B, Brady, L W, Topolsky, D, Bulova, S, Vonderheid, E C, Brodsky, I

“…Patients with advanced stage cutaneous T cell lymphoma (CTCL) have a median survival of 2-5 years with no currently available curative therapy. This limited…”
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Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma by Kari, Laszlo, Loboda, Andrey, Nebozhyn, Michael, Rook, Alain H, Vonderheid, Eric C, Nichols, Calen, Virok, Dezso, Chang, Celia, Horng, Wen-Hwai, Johnston, James, Wysocka, Maria, Showe, Michael K, Showe, Louise C

“…We have used cDNA arrays to investigate gene expression patterns in peripheral blood mononuclear cells from patients with leukemic forms of cutaneous T cell…”
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Long-term efficacy, curative potential, and carcinogenicity of topical mechlorethamine chemotherapy in cutaneous T cell lymphoma by Vonderheid, E C, Tan, E T, Kantor, A F, Shrager, L, Micaily, B, Van Scott, E J

“…Complete responses lasting from 4 to 14 years were documented in 65 of 331 (20%) patients with cutaneous T cell lymphoma treated with topical mechlorethamine…”
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