Search Results - "Vonderhaar, Emily P."

STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models by Jing, Weiqing, McAllister, Donna, Vonderhaar, Emily P, Palen, Katie, Riese, Matthew J, Gershan, Jill, Johnson, Bryon D, Dwinell, Michael B

“…Pancreatic cancer is characterized by an immune suppressive stromal reaction that creates a barrier to therapy. A murine transgenic pancreatic cancer cell line…”
Get full text

Targeted immune activation in pediatric solid tumors: opportunities to complement local control approaches by Vonderhaar, Emily P, Dwinell, Michael B, Craig, Brian T

“…Surgery or radiation therapy is nearly universally applied for pediatric solid tumors. In many cases, in diverse tumor types, distant metastatic disease is…”
Get full text

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer by Vonderhaar, Emily P., Barnekow, Nicholas S., McAllister, Donna, McOlash, Laura, Eid, Mahmoud Abu, Riese, Matthew J., Tarakanova, Vera L., Johnson, Bryon D., Dwinell, Michael B.

“…Pancreatic ductal adenocarcinoma (PDA) is a lethal chemoresistant cancer that exhibits early metastatic spread. The highly immunosuppressive PDA tumor…”
Get full text

Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma by Roy, Ishan, Boyle, Kathleen A, Vonderhaar, Emily P, Zimmerman, Noah P, Gorse, Egal, Mackinnon, A Craig, Hwang, Rosa F, Franco-Barraza, Janusz, Cukierman, Edna, Tsai, Susan, Evans, Douglas B, Dwinell, Michael B

“…The mechanisms by which the extreme desmoplasia observed in pancreatic tumors develops remain unknown and its role in pancreatic cancer progression is…”
Get full text

Type I Interferon Counteracts Antiviral Effects of Statins in the Context of Gammaherpesvirus Infection by Lange, Philip T, Darrah, Eric J, Vonderhaar, Emily P, Mboko, Wadzanai P, Rekow, Michaela M, Patel, Shailendra B, Sidjanin, Duska J, Tarakanova, Vera L

“…The cholesterol synthesis pathway is a ubiquitous cellular biosynthetic pathway that is attenuated therapeutically by statins. Importantly, type I interferon…”
Get full text

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic CancerSummary by Emily P. Vonderhaar, Nicholas S. Barnekow, Donna McAllister, Laura McOlash, Mahmoud Abu Eid, Matthew J. Riese, Vera L. Tarakanova, Bryon D. Johnson, Michael B. Dwinell

“…Background & Aims: Pancreatic ductal adenocarcinoma (PDA) is a lethal chemoresistant cancer that exhibits early metastatic spread. The highly immunosuppressive…”
Get full text